Patents by Inventor Christian Maasch

Christian Maasch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C5a binding nucleic acids
    Patent number: 11492625
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5? AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3? [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2?-deoxyribonucleotides.
    Type: Grant
    Filed: March 15, 2020
    Date of Patent: November 8, 2022
    Assignee: APTARION biotech AG
    Inventors: Kai Hohlig, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • CXCL8 Binding Nucleic Acids
    Publication number: 20210403913
    Abstract: The present invention is related to an L-nucleic acid molecule capable of binding to human CXCL8, wherein the L-nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5?-GG A AGU ACGUGGA AAGCCRA(Xu)RAGUGUGUCCCG-3? [SEQ. ID. NO: 27], wherein Xu is U or absent.
    Type: Application
    Filed: November 12, 2019
    Publication date: December 30, 2021
    Applicant: Aptarion Biotech AG
    Inventors: Kai Hohlig, Axel Vater, Werner Purschke, Dirk Zboralski, Christian Maasch
  • New C5a Binding Nucleic Acids
    Publication number: 20210163946
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5? AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3? [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2?-deoxyribonucleotides.
    Type: Application
    Filed: March 15, 2020
    Publication date: June 3, 2021
    Applicant: Aptarion Biotech AG
    Inventors: Kai Hohlig, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • SDF-1 Binding Nucleic Acids
    Publication number: 20210139909
    Abstract: The present invention is related to a nucleic acid molecule, preferably binding to SDF-I, selected from the group comprising type A nucleic acid molecules, type B nucleic acid molecules, type C nucleic acid molecules and nucleic acid molecules having a nucleic acid sequence according to any of SEQ. ID. No. 142, SEQ. ID. No. 143 and SEQ. ID. No. 144.
    Type: Application
    Filed: November 9, 2020
    Publication date: May 13, 2021
    Applicant: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • IMMOBILISATION OF NUCLEIC ACIDS ON SURFACES
    Publication number: 20200087147
    Abstract: The present invention relates to the immobilisation of nucleic acids or other biomolecules on surfaces which are suitable amongst other purposes for biosensors. The invention provides a method and use of an azide-terminated CNM that may be functionalised by coupling of receptors or oligonucleotides.
    Type: Application
    Filed: June 1, 2018
    Publication date: March 19, 2020
    Inventors: Albert Schnieders, Nikolaus Meyerbröker, Axel Vater, Christian Maasch, Lucas Bethge
  • C5a binding nucleic acids
    Patent number: 10590424
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5? AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3? [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2?-deoxyribonucleotides.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: March 17, 2020
    Assignee: NOXXON Pharma AG
    Inventors: Kai Hohlig, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same
    Publication number: 20190367921
    Abstract: The present invention is related to a method for generating a nucleic acid molecule capable of binding to a target molecule comprising the following steps: a) providing a reference nucleic acid molecule, wherein the reference nucleic acid molecule is capable of binding to the target molecule and wherein the reference nucleic acid molecule comprises a sequence of nucleotides, wherein the sequence of nucleotides comprises n nucleotides; b) preparing a first level derivative of the reference nucleic acid molecule, wherein the first level derivative of the reference nucleic acid molecule differs from the reference nucleic acid molecule at one nucleotide position, wherein the first level derivative is prepared by replacing the ribonucleotide at the one nucleotide position by a 2?-deoxyribonucleotide in case the reference nucleic acid has a ribonucleotide at the nucleotide position and wherein the first level derivative is prepared by replacing the 2?-deoxyribonucleotide at the one nucleotide position by a ribonucl
    Type: Application
    Filed: May 21, 2018
    Publication date: December 5, 2019
    Inventors: Florian Jarosch, Sven Klussmann, Simone Sell, Werner Purschke, Christian Maasch, Axel Vater, Kai Hohlig
  • MCP-1 binding nucleic acids
    Patent number: 10273480
    Abstract: The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group comprising type 1A nucleic acids, type 1B nucleic acids, type 2 nucleic acids, type 3 nucleic acids, type 4 nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ.ID.No. 87 to 115.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: April 30, 2019
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • SDF-1 binding nucleic acids and the use thereof in cancer treatment
    Patent number: 10093934
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to SDF-1, preferably capable of inhibiting SDF-1, whereby the nucleic acid molecule is for use in a method for the treatment and/or prevention of a disease or disorder, for use in a method for the treatment of a subject suffering from a disease or disorder or being at risk of developing a disease or disorder as an adjunct therapy, or for use as a medicament for the treatment and/or prevention of a disease or disorder, whereby the disease or disorder is cancer.
    Type: Grant
    Filed: July 3, 2016
    Date of Patent: October 9, 2018
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse, Dirk Zboralski
  • C5a Binding Nucleic Acids
    Publication number: 20180223285
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5? AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3? [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2?-deoxyribonucleotides.
    Type: Application
    Filed: December 12, 2016
    Publication date: August 9, 2018
    Applicant: NOXXON Pharma AG
    Inventors: Kai Hohlig, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • SDF-1 Binding Nucleic Acids
    Publication number: 20180163207
    Abstract: The present invention is related to an L nucleic acid that binds to an SDF-1.
    Type: Application
    Filed: November 20, 2017
    Publication date: June 14, 2018
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • SDF-1 binding nucleic acids and the use thereof
    Patent number: 9988636
    Abstract: The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: June 5, 2018
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same
    Patent number: 9976145
    Abstract: The present invention is related to a method for generating a nucleic acid molecule capable of binding to a target molecule comprising the following steps: a) providing a reference nucleic acid molecule, wherein the reference nucleic acid molecule is capable of binding to the target molecule and wherein the reference nucleic acid molecule comprises a sequence of nucleotides, wherein the sequence of nucleotides comprises n nucleotides; b) preparing a first level derivative of the reference nucleic acid molecule, wherein the first level derivative of the reference nucleic acid molecule differs from the reference nucleic acid molecule at one nucleotide position, wherein the first level derivative is prepared by replacing the ribonucleotide at the one nucleotide position by a 2?-deoxyribonucleotide in case the reference nucleic acid has a ribonucleotide at the nucleotide position and wherein the first level derivative is prepared by replacing the 2?-deoxyribonucleotide at the one nucleotide position by a ribonucl
    Type: Grant
    Filed: January 10, 2012
    Date of Patent: May 22, 2018
    Assignee: NOXXON Pharma AG
    Inventors: Florian Jarosch, Sven Klussmann, Simone Sell, Werner Purschke, Christian Maasch, Axel Vater, Kai Hohlig
  • MCP-1 Binding Nucleic Acids
    Publication number: 20180066265
    Abstract: The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group comprising type 1A nucleic acids, type 1B nucleic acids, type 2 nucleic acids, type 3 nucleic acids, type 4 nucleic acids and nucleic acids having a nucleic acid sequence according to any of SEQ.ID.No. 87 to 115.
    Type: Application
    Filed: June 6, 2017
    Publication date: March 8, 2018
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • SDF-1 binding nucleic acids
    Patent number: 9822369
    Abstract: The present invention is related to an L nucleic acid that binds to an SDF-1.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: November 21, 2017
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • MCP-1 binding nucleic acids
    Patent number: 9670491
    Abstract: The present invention is related to a nucleic acid, preferably binding to MCP-1, selected from the group consisting of Type 1A nucleic acids, type 1B nucleic acids, Type 2 nucleic acids, Type 3 nucleic acids, Type 4 nucleic acids and nucleic acids comprising SEQ ID NOs:87-115
    Type: Grant
    Filed: April 6, 2014
    Date of Patent: June 6, 2017
    Assignee: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch
  • C5a binding nucleic acids
    Patent number: 9518265
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5? AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3? [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2?-deoxyribonucleotides.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: December 13, 2016
    Assignee: NOXXON Pharma AG
    Inventors: Kai Hohlig, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • SDF-1 binding nucleic acids and the use thereof in cancer treatment
    Publication number: 20160355821
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to SDF-1, preferably capable of inhibiting SDF-1, whereby the nucleic acid molecule is for use in a method for the treatment and/or prevention of a disease or disorder, for use in a method for the treatment of a subject suffering from a disease or disorder or being at risk of developing a disease or disorder as an adjunct therapy, or for use as a medicament for the treatment and/or prevention of a disease or disorder, whereby the disease or disorder is cancer.
    Type: Application
    Filed: July 3, 2016
    Publication date: December 8, 2016
    Applicant: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse, Dirk Zboralski
  • SDF-1 Binding Nucleic Acids and the Use Thereof
    Publication number: 20160326531
    Abstract: The present invention is related to a nucleic acid molecule binding to SDF-1, whereby the nucleic acid molecule influences migration of cells.
    Type: Application
    Filed: July 26, 2016
    Publication date: November 10, 2016
    Applicant: NOXXON Pharma AG
    Inventors: Werner Purschke, Florian Jarosch, Dirk Eulberg, Sven Klussmann, Klaus Buchner, Christian Maasch, Nicole Dinse
  • Hepcidin Binding Nucleic Acids
    Publication number: 20160257958
    Abstract: The present invention is related to a nucleic acid capable of binding to hepcidin.
    Type: Application
    Filed: September 23, 2014
    Publication date: September 8, 2016
    Inventors: Simone Sell, Frank Morich, Christian Maasch, Sven Klussmann, Nicole Dinse, Klaus Buchner, Frank Schwobel