Patents by Inventor Christian MITTELHOLZER

Christian MITTELHOLZER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOLOGICALLY PRODUCED NUCLEIC ACID FOR VACCINE PRODUCTION
    Publication number: 20250188127
    Abstract: The invention relates to a biologically produced nucleic acid sequence comprising two or three primary nucleic acid sequence parts of SARS-COV-2 and not more than three secondary nucleic acid sequence parts, wherein a secondary nucleic acid sequence part encodes an amino acid sequence having the function of a SARS-COV-2 amino acid sequence encoded by ORF3a, ORF6, ORF7a or ORF8. The invention further relates to a host cell or a kit for producing the nucleic acid of the invention, a vector encoding the nucleic acid of the invention and products that can be obtained by the expression of the nucleic acid of the invention such as virus envelopes. The invention further relates a pharmaceutical composition comprising the nucleic acid of the invention or products derived thereof, preferably for use in the prevention of SARS-COV-2.
    Type: Application
    Filed: September 9, 2022
    Publication date: June 12, 2025
    Applicant: Universität Basel
    Inventors: Enja Tatjana KIPFER, Thomas KLIMKAIT, Christian MITTELHOLZER, Fabian OTTE
  • FLAGELLIN-CONTAINING PROTEIN NANOPARTICLES AS A VACCINE PLATFORM
    Publication number: 20160324958
    Abstract: The present invention relates to self-assembling protein nanoparticles constructed from suitable oligomerization domains and further incorporating the TLR5 binding protein flagellin as an adjuvant molecule. Furthermore, the invention relates to the use of such nanoparticles for vaccination.
    Type: Application
    Filed: January 9, 2015
    Publication date: November 10, 2016
    Applicant: ALPHA-O PEPTIDES AG
    Inventors: Peter BURKHARD, Senthil Kumar RAMAN, Sara Maria PAULILLO, Matteo PIAZZA, Caroline KULANGARA, Christian MITTELHOLZER