Patents by Inventor Christian OBINGER

Christian OBINGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligand regulated protein-protein interaction system
    Patent number: 12102653
    Abstract: A ligand regulated protein-protein interaction system based on a lipocalin-fold molecule including: (a) a lipocalin-fold molecule; (b) a lipocalin-fold ligand with a low molecular weight of 1500 Da or below; and (c) a lipocalin-fold binding interaction partner, wherein the lipocalin-fold molecule can bind to the lipocalin-fold ligand; and wherein the lipocalin-fold molecule bound to the lipocalin-fold ligand binds to the lipocalin-fold binding interaction partner with an affinity which is at least 10-fold higher than the affinity of the lipocalin-fold molecule not bound to the lipocalin-fold ligand; and wherein the lipocalin-fold binding interaction partner is not a naturally occurring protein which has an affinity of <10 ?M to any naturally occurring lipocalin-fold molecule in the presence of any lipocalin-fold ligand.
    Type: Grant
    Filed: May 4, 2023
    Date of Patent: October 1, 2024
    Assignees: ST. ANNA KINDERKREBSFORSCHUNG, UNIVERSITÄT FÜR BODENKULTUR WIEN
    Inventors: Michael Traxlmayr, Christian Obinger, Charlotte Brey, Manfred Lehner
  • LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM
    Publication number: 20240000841
    Abstract: A ligand regulated protein-protein interaction system based on a lipocalin-fold molecule including: (a) a lipocalin-fold molecule; (b) a lipocalin-fold ligand with a low molecular weight of 1500 Da or below; and (c) a lipocalin-fold binding interaction partner, wherein the lipocalin-fold molecule can bind to the lipocalin-fold ligand; and wherein the lipocalin-fold molecule bound to the lipocalin-fold ligand binds to the lipocalin-fold binding interaction partner with an affinity which is at least 10-fold higher than the affinity of the lipocalin-fold molecule not bound to the lipocalin-fold ligand; and wherein the lipocalin-fold binding interaction partner is not a naturally occurring protein which has an affinity of <10 ?M to any naturally occurring lipocalin-fold molecule in the presence of any lipocalin-fold ligand.
    Type: Application
    Filed: May 4, 2023
    Publication date: January 4, 2024
    Inventors: Michael TRAXLMAYR, Christian OBINGER, Charlotte BREY, Manfred LEHNER
  • Ligand regulated protein-protein interaction system
    Patent number: 11844813
    Abstract: A ligand regulated protein-protein interaction system based on a lipocalin-fold molecule including: (a) a lipocalin-fold molecule; (b) a lipocalin-fold ligand with a low molecular weight of 1500 Da or below; and (c) a lipocalin-fold binding interaction partner; wherein the lipocalin-fold molecule can bind to the lipocalin-fold ligand; and wherein the lipocalin-fold molecule bound to the lipocalin-fold ligand binds to the lipocalin-fold binding interaction partner with an affinity which is at least 10-fold higher than the affinity of the lipocalin-fold molecule not bound to the lipocalin-fold ligand; and wherein the lipocalin-fold binding interaction partner is not a naturally occurring protein which has an affinity of <10 ?M to any naturally occurring lipocalin-fold molecule in the presence of any lipocalin-fold ligand.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: December 19, 2023
    Assignees: ST. ANNA KINDERKREBSFORSCHUNG, UNIVERSITÄT FÜR BODENKULTUR WIEN
    Inventors: Michael Traxlmayr, Christian Obinger, Charlotte Brey, Manfred Lehner
  • LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM
    Publication number: 20200390813
    Abstract: A ligand regulated protein-protein interaction system based on a lipocalin-fold molecule including: (a) a lipocalin-fold molecule; (b) a lipocalin-fold ligand with a low molecular weight of 1500 Da or below; and (c) a lipocalin-fold binding interaction partner; wherein the lipocalin-fold molecule can bind to the lipocalin-fold ligand; and wherein the lipocalin-fold molecule bound to the lipocalin-fold ligand binds to the lipocalin-fold binding interaction partner with an affinity which is at least 10-fold higher than the affinity of the lipocalin-fold molecule not bound to the lipocalin-fold ligand; and wherein the lipocalin-fold binding interaction partner is not a naturally occurring protein which has an affinity of <10 ?M to any naturally occurring lipocalin-fold molecule in the presence of any lipocalin-fold ligand.
    Type: Application
    Filed: December 20, 2018
    Publication date: December 17, 2020
    Inventors: Michael TRAXLMAYR, Christian OBINGER, Charlotte BREY, Manfred LEHNER