Abstract: The invention relates to a drinking water supply system including a drinking water line system, a plurality of drinking water withdrawal points connected to the drinking water line system, at least one sensor which is designed to determine measuring values, a central control device which is designed to receive and evaluate the measuring values determined by the at least one sensor, a plurality of decentralized control elements which are designed to influence at different locations in the drinking water supply system one or more properties of the water guided in the drinking water supply system, wherein the central control device is designed to control the control elements for influencing the one or more properties of the water guided in the drinking water supply system, and wherein a plurality of control elements are or can be combined to form a virtual group.

Abstract: A drinking water supply system includes a drinking water line system, a plurality of drinking water withdrawal points connected to the drinking water line system, at least one sensor which is designed to determine measuring values, and a central control device which is designed to receive and evaluate the measuring values determined by the at least one sensor. The system also includes a presence detector designed to determine information about the presence of a person, or an acoustic sensor designed to measure measuring values for the volume. The central control device is designed to control the drinking water supply system as a function of the information about the presence of a person or as a function of the measured values for the volume. A method for controlling such a drinking water supply system and a computer program that causes the method to be carried out are also provided.

Abstract: A drinking water supply system with a drinking water line system includes multiple drinking water removal points connected to the drinking water line system, at least one sensor, which is designed to determine measurement values, and a central controller, which is designed to receive and evaluate the measurement values determined by the at least one sensor. The central controller is designed to control the control elements depending on the received measurement values. The drinking water line system has a drinking water line section for supplying drinking water to multiple drinking water removal points. A volumetric flow rate sensor is provided in order to measure the volumetric flow rate of the water in the drinking water line section and/or a pressure sensor is provided in order to measure the water pressure in the drinking water line section. The controller is designed to carry out a measure.

Abstract: The present invention is related to a formulation of the prolactin receptor antibody mat3 and its use in the treatment of male and female pattern hair loss.

Abstract: A drinking water supply system includes a drinking water line system, a plurality of drinking water withdrawal points connected to the drinking water line system, at least one sensor which is designed to determine measuring values, and a central control device which is designed to receive and evaluate the measuring values determined by the at least one sensor. The system also includes a presence detector designed to determine information about the presence of a person, or an acoustic sensor designed to measure measuring values for the volume. The central control device is designed to control the drinking water supply system as a function of the information about the presence of a person or as a function of the measured values for the volume. A method for controlling such a drinking water supply system and a computer program that causes the method to be carried out are also provided.

Abstract: A drinking water supply system with a drinking water line system includes multiple drinking water removal points connected to the drinking water line system, at least one sensor, which is designed to determine measurement values, and a central controller, which is designed to receive and evaluate the measurement values determined by the at least one sensor. The central controller is designed to control the control elements depending on the received measurement values. The drinking water line system has a drinking water line section for supplying drinking water to multiple drinking water removal points. A volumetric flow rate sensor is provided in order to measure the volumetric flow rate of the water in the drinking water line section and/or a pressure sensor is provided in order to measure the water pressure in the drinking water line section. The controller is designed to carry out a measure.

Abstract: The invention relates to a drinking water supply system including a drinking water line system, a plurality of drinking water withdrawal points connected to the drinking water line system, at least one sensor which is designed to determine measuring values, a central control device which is designed to receive and evaluate the measuring values determined by the at least one sensor, a plurality of decentralized control elements which are designed to influence at different locations in the drinking water supply system one or more properties of the water guided in the drinking water supply system, wherein the central control device is designed to control the control elements for influencing the one or more properties of the water guided in the drinking water supply system, and wherein a plurality of control elements are or can be combined to form a virtual group.

Abstract: A drinking water supply system with a drinking water line system includes multiple drinking water removal points connected to the drinking water line system, at least one sensor, which is designed to determine measurement values, and a central controller, which is designed to receive and evaluate measurement values determined by the at least one sensor. Multiple sensors are provided which are designed to determine measurement values for one property or for different properties of the water being conducted in the drinking water supply system at different locations in the drinking water supply system, and the central controller is designed to receive and evaluate the measurement values determined by the sensors. One or more of the sensors is designed to determine measurement values for the drinking water quality of the water being conducted in the drinking water supply system. A method for controlling such a supply system is also provided.

Abstract: The invention relates to selective adrenoreceptor ?2C receptor antagonists alone, or in combination with chymase inhibitors for use in the treatment and/or prophylaxis of peripheral artery diseases (PAD) and/or critical limb ischemia (CLI).

Abstract: A buoy corrosion detection system includes a buoy having a double hull section in which the outer hull is designed to corrode and fail prior to the rest of the hull. The double hull section is positioned at the waterline, which is the area most prone to corrosion. As the outer hull corrodes, water passes through the hull and is detected by a moisture detector. The moisture detector then relays a signal that water has entered through the hull, and a signaling circuit then sends a communication signal to the user indicating that the buoy has corrosion. The buoy corrosion detection system leads to an “as-needed” maintenance cycle for buoys.

Abstract: A buoy corrosion detection system includes a buoy having a double hull section in which the outer hull is designed to corrode and fail prior to the rest of the hull. The double hull section is positioned at the waterline, which is the area most prone to corrosion. As the outer hull corrodes, water passes through the hull and is detected by a moisture detector. The moisture detector then relays a signal that water has entered through the hull, and a signaling circuit then sends a communication signal to the user indicating that the buoy has corrosion. The buoy corrosion detection system leads to an “as-needed” maintenance cycle for buoys.

Abstract: The system for management of rack and tube positions for clinical chemistry laboratories includes tubes (10) capable of containing human biological material, a rack (20) configured for receiving and/or holding the tubes (10) to be stocked, a supporting base (30) configured for supporting the rack (20) thereon, a reader (50) configured for reading an identifier (RID) of the rack (20) to be put onto the supporting base (30) and an identifier (TID) of the tube to be put into the rack (20), a camera (40) for detecting the rack (20) on the supporting base (30), and at least one of the tubes (10) into the rack (20), a processing unit (60) for mapping the detected rack (20) into a plurality of allowed positions (Pi) and the detected tube (10) into a tube position (P) included in the plurality of allowed positions (Pi).

Abstract: The present invention is directed to the neutralizing prolactin receptor antibody Mat3, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation and for the treatment and prevention of antiestrogen-resistant breast cancer. The antibody of the invention blocks prolactin receptor-mediated signalling.

Abstract: The present invention is directed to the neutralizing prolactin receptor antibody 006-H08, as well as maturated forms thereof, and antigen-binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The antibodies of the invention block prolactin receptor-mediated signaling.

Abstract: The present invention is directed to the neutralizing prolactin receptor antibody Mat3, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation and for the treatment and prevention of antiestrogen-resistant breast cancer. The antibody of the invention blocks prolactin receptor-mediated signalling.

Abstract: An electronic device for outputting a location reference using an attribute value which is assigned to a location to be referenced is provided, wherein the device comprises a memory, a processor system and a data transmission unit. The memory serves for storing and providing a list with attribute values for location referencing, the list consisting of a subset of all attribute values depending on a frequency of the individual attribute values. The processor system is adapted to receive an indication of a location, to determine at least one attribute value which is suitable for location referencing of the location, and for reading out, from the memory, an index value which is assigned to the determined attribute value in the list. The data transmission unit serves for outputting the read-out index value to a further device.

Abstract: The neutralizing prolactin receptor antibody Mat3, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation and for the treatment and prevention of antiestrogen-resistant breast cancer. The antibody blocks prolactin receptor-mediated signalling.

Abstract: The invention relates to a plug (1), with a first plug-and-socket connector (5) and at least a second plug-and-socket connector (4) in which the first plug-and-socket connector (5) can be received, and with a surrounding housing (6) in which the second plug-and-socket connector (4) can be received non-displaceably in at least one securing direction (A). Furthermore, the invention relates to a mating plug (2) with a first mating connector (7) and at least a second mating connector (2a), in which the first mating connector (7) can be received.

Abstract: The present invention is directed to the neutralizing prolactin receptor antibody 005-C04, as well as maturated forms thereof, and antigen binding fragments, pharmaceutical compositions containing them and their use in the treatment or prevention of benign disorders and indications mediated by the prolactin receptor such as endometriosis, adenomyosis, non-hormonal female contraception, benign breast disease and mastalgia, lactation inhibition, benign prostate hyperplasia, fibroids, hyper- and normoprolactinemic hair loss, and cotreatment in combined hormone therapy to inhibit mammary epithelial cell proliferation. The antibodies of the invention block prolactin receptor-mediated signaling.

Abstract: The present invention relates to a plug element (1, 1?, 1?, 1??, 1??) with a plugging section (2) which is configured to be able to be brought together in a direction of plugging (Z) of the plug element (1, 1?, 1?, 1??, 1??) with a mating plug element (100) and has at least one receptacle (5) for an electrical plug-in contact, and with a contact lock member (8) which, at least in its securing position (S), projects, at least in sections, into the receptacle (5). In order, with the smallest possible external dimensions of the plug element (1, 1?, 1?, 1??, 1??), to be able simply to feel that the securing position (S) has been reached, provision is made according to the invention for the contact lock member (8) in the securing position (S) to release a test path (P) along which a test member (3, 200) can be moved past a test stop (18).