Abstract: The present invention relates to hAM15-52 analogues with improved amylin receptor (hAMY3R) potency (hAMY3R-EC50?250 pM) and which are largely based on the sequence of the human adrenomedullin fragment hAM15-52. The invention further relates to hAM15-52 analogues that are selective amylin receptor (hAMY3R) agonists (hAMY3R-EC50?250 pM and an hAM1R-EC50?25 nM) and which are largely based on the sequence of the human adrenomedullin fragment hAM15-52. The hAM15-52 analogues according to the invention maintain the good physical stability of hAM15-52. The invention further relates to pharmaceutical compositions comprising such polypeptides and their use in the treatment of a medical condition such as obesity, NASH and/or diabetes.

Abstract: A system for alignment of big bags prior to product filling. The system includes a first alignment arrangement configured to rotate an inflated big bag. The first alignment arrangement including a first drive configured to operate a first rotation part, a counter hold, and a displacement arrangement for displacing the first alignment arrangement and/or the counter hold relative to a big bag. The system may include a sensor arrangement configured to detect a rotational orientation of the inflated big bag and adapted to provide a sensor output based thereon, and a controller configured to receive the sensor output and control the first drive to rotate the inflated big bag based on the sensor output. A method of alignment of big bags prior to product filling, a computer program configured for executing acts of the method and a computer readable medium for storing the computer program.

Abstract: The present invention relates to a single mode or single dominating mode microwave reactor, a single dominating mode microwave reactor system and a method of producing fuel, such as biofuel.

Abstract: Described herein are methods and systems for detecting electrical discharges that precede electrical fires in electrical wiring. One or more sensor devices coupled to a circuit detect one or more signal waveforms generated by electrical activity on the circuit. The sensor devices identify one or more transient signals within the one or more signal waveforms, and generate one or more transient characteristics based upon the identified transient signals. A server communicably coupled to the sensor devices receives the one or more transient characteristics. The server analyzes the one or more transient characteristics to identify one or more electrical discharge indications. The server generates one or more alert signals when one or more electrical discharge indications are identified.

Abstract: Methods and apparatuses for automatic analysis and optimization of an audio signal are described herein. An example method may comprise receiving, by an audio signal optimizer, a first indication to perform an audio signal optimization, receiving an audio signal from an input device, recording a sample of the audio signal, analyzing the sample of the audio signal for at least one audio parameter, and performing, based on an analysis of the sample of the audio signal, the audio signal optimization of the audio signal, wherein the audio signal optimization comprises a configuration of a gain level of the audio signal.

Abstract: A mixer includes a mixing chamber and a motor mechanically connected to the mixing chamber. The mixing chamber comprises a suspended elongate rigid tube section having a top end and an open bottom end, and a flexible tube section extending downwards from the open bottom end. The motor comprises a vibration motor mechanically coupled to the suspended elongate rigid tube section at the top end of the suspended elongate rigid tube section.

Abstract: A microphone may comprise a microphone element for detecting sound, and a digital signal processor configured to process a first audio signal that is based on the sound in accordance with a selected one of a plurality of digital signal processing (DSP) modes. Each of the DSP modes may be for processing the first audio signal in a different way. For example, the DSP modes may account for distance of the person speaking (e.g., near versus far) and/or desired tone (e.g., darker, neutral, or bright tone). At least some of the modes may have, for example, an automatic level control setting to provide a more consistent volume as the user changes their distance from the microphone or changes their speaking level, and that may be associated with particular default (and/or adjustable) values of the parameters attack, hold, decay, maximum gain, and/or target gain, each depending upon which DSP is being applied.

Abstract: A microphone may comprise a microphone element for detecting sound, and a digital signal processor configured to process a first audio signal that is based on the sound in accordance with a selected one of a plurality of digital signal processing (DSP) modes. Each of the DSP modes may be for processing the first audio signal in a different way. For example, the DSP modes may account for distance of the person speaking (e.g., near versus far) and/or desired tone (e.g., darker, neutral, or bright tone). At least some of the modes may have, for example, an automatic level control setting to provide a more consistent volume as the user changes their distance from the microphone or changes their speaking level, and that may be associated with particular default (and/or adjustable) values of the parameters attack, hold, decay, maximum gain, and/or target gain, each depending upon which DSP is being applied.

Abstract: A microphone having a multi-channel mixer and one or more connectors usable to receive and/or output audio. Any of the connectors may be used as an input connector, as an output connector, or configured to be switchable between being an input and an output connector. The user of the microphone may be able to conveniently use one or more of the connectors to expand the microphone to become part of a larger setup that uses multiple microphones. For example, an XLR connector of the microphone may be passive, and may be configured such that a user can daisy chain the output from an XLR connector of another microphone into an XLR connector of the microphone. In such an arrangement, an output based on one or both of the microphones may be output through another connector of the microphone, such as a USB connector.

Abstract: A microphone may comprise a microphone element for detecting sound, and a digital signal processor configured to process a first audio signal that is based on the sound in accordance with a selected one of a plurality of digital signal processing (DSP) modes. Each of the DSP modes may be for processing the first audio signal in a different way. For example, the DSP modes may account for distance of the person speaking (e.g., near versus far) and/or desired tone (e.g., darker, neutral, or bright tone). At least some of the modes may have, for example, an automatic level control setting to provide a more consistent volume as the user changes their distance from the microphone or changes their speaking level, and that may be associated with particular default (and/or adjustable) values of the parameters attack, hold, decay, maximum gain, and/or target gain, each depending upon which DSP is being applied.

Abstract: A communication system, a communication device and related method, the communication device comprising a processor, a source interface comprising a first source interface for a first external source, and an output interface, wherein the processor is configured to obtain, e.g. receive, a first input signal via the first source interface, obtain a first complementing signal, combine the first input signal and the first complementing signal to a first combined signal, apply a first filter function to the first combined signal for provision of a first left output signal and a first right output signal, the first filter function comprising one or more head related transfer functions, and output a left output signal and a right output signal via the output interface, wherein the left output signal is based on the first left output signal and the right output signal is based on the first right output signal.

Abstract: The invention provides an infrared upconversion spectrometer for determining a mid-IR spectrum of received infrared light with a high resolution. The spectrometer applies upconversion to transform light in the mid-IR to the near-IR range where efficient detectors are available. The up-conversion causes divergence of the light, and in addition, the invention applies an extra dispersive element to record a spectrum.

Abstract: A system for measuring velocity of particles such as particles in air is a Light Detection and Ranging (LIDAR) system, having a micro-electro-mechanical-system (MEMS).

Abstract: The invention relates to a coaxial direct-detection LIDAR system for measuring velocity, temperature and/or particulate density. The system comprises a laser source for emitting a laser light beam having a lasing center frequency along an emission path. The system further comprises an optical delivery system arranged in the emission path of the laser source, the optical delivery system being arranged for delivering the laser light beam in a measuring direction, the optical delivery system further being configured for collecting a return signal backscattered along the measuring direction. Finally, the system comprises a detector system arranged to receive the return signal from the optical delivery system, the detector system comprising a narrowband optical filter and a detector, the narrowband optical filter having a filter center frequency of a pass-band, wherein the center lasing frequency and/or the center filter frequency may be scanned.

Abstract: A communication system, a communication device and related method, the communication device comprising a processor, a source interface comprising a first source interface for a first external source, and an output interface, wherein the processor is configured to obtain, e.g. receive, a first input signal via the first source interface, obtain a first complementing signal, combine the first input signal and the first complementing signal to a first combined signal, apply a first filter function to the first combined signal for provision of a first left output signal and a first right output signal, the first filter function comprising one or more head related transfer functions, and output a left output signal and a right output signal via the output interface, wherein the left output signal is based on the first left output signal and the right output signal is based on the first right output signal.

Abstract: The invention provides an infrared upconversion spectrometer for determining a mid-IR spectrum of received infrared light with a high resolution. The spectrometer applies upconversion to transform light in the mid-IR to the near-IR range where efficient detectors are available. The up-conversion causes divergence of the light, and in addition, the invention applies an extra dispersive element to record a spectrum.

Abstract: A system for measuring velocity of particles such as particles in air is a Light Detection and Ranging (LIDAR) system, having a micro-electro-mechanical-system (MEMS).

Abstract: Disclosed are methods and systems for analyzing images of specimens processed by a programmable quantitative assay or more specifically a robust programmable quantitative dot assay, PDQA, that enable specimens to be imaged and assessed across a wide variety of conditions and applications. Specific embodiments directed to immunohistochemical applications provide more quantitative methods of imaging and assessing biological samples including tissue samples.

Abstract: The present invention relates to a low-cost LIDAR system. The system may be integrated in a wind turbine for measurement of the approaching wind field. One embodiment relates to a LIDAR system comprising a beam generating section adapted for generating a substantially linearly polarized output beam, and a beam steering section comprising a first optical device for controllably altering the polarization of the output beam, said first optical device in optical connection with a first polarizing beam splitter, said beam steering section adapted for directing the outputbeam interchangeably between a first direction and a second direction.