Abstract: The present invention relates to hAM15-52 analogues with improved amylin receptor (hAMY3R) potency (hAMY3R-EC50?250 pM) and which are largely based on the sequence of the human adrenomedullin fragment hAM15-52. The invention further relates to hAM15-52 analogues that are selective amylin receptor (hAMY3R) agonists (hAMY3R-EC50?250 pM and an hAM1R-EC50?25 nM) and which are largely based on the sequence of the human adrenomedullin fragment hAM15-52. The hAM15-52 analogues according to the invention maintain the good physical stability of hAM15-52. The invention further relates to pharmaceutical compositions comprising such polypeptides and their use in the treatment of a medical condition such as obesity, NASH and/or diabetes.

Abstract: The invention relates to a treatment head (1) for treating kegs (3), each of which is equipped with at least one keg fitting (2). The treatment head (1) has a treatment head housing (4), as well as at least one plunger (5), which is held in the treatment head housing (4) so as to be displaceable in the axial direction of a treatment head axis (BA), for opening the keg fitting (2) of the keg (3) which is to be treated and is disposed in a sealing position on the treatment head (1). At least one fluid space (6) as well as flow paths or conduits (SK1, SK2) which communicate controllably with the fluid space (6) are formed in the treatment head (1). The flow paths or conduits (SK1, SK2) can be connected to the interior (3.1) of the keg (3) to be treated when the keg fitting (2) is open.

Abstract: The invention relates to a system (10) for treating kegs (12), comprising: at least two treatment modules (14a-14g), each of which has—a keg receiving area (35) for receiving at least one keg (12) during the treatment process, —a treatment head (36) for treating the keg (12), and—at least one interface (41) for a discharge and for at least one cleaning medium line and/or for at least one filling product line; and a controller (30) for controlling the treatment modules (14a-14g), wherein at least one of the treatment modules (14a-14g) is designed to treat kegs (12) of a first type and/or of a first size, and at least one other treatment module of the treatment modules (14a-14g) is designed to treat kegs (12) of a second type and/or of a second size.

Abstract: The present invention relates to a compressor system (1) comprising: a high-pressure diaphragm gas compressor (2) having a compressor inlet (3) and a compressor outlet (4). Wherein an inlet volume (5) is defined between a compressor inlet valve (6) and said compressor inlet, said compressor outlet is fluidly connected to a receiving vessel (7). A motor (8) configured to drive a crankshaft of said compressor. A controller (9) configured to control operation of said compressor, said compressor inlet valve and said motor, during a plurality of successive operation cycles. Wherein during a shut-down part of an operation cycle, said compressor inlet valve is configured for being closed before said crankshaft stop rotation, and wherein during a start-up part of a subsequent operation cycle, said compressor inlet valve is configured for being opened after at least one completed compression stroke.

Abstract: The disclosure relates to an internal combustion engine having multiple camshaft control units which are connected to one another in a line by a first network topology and via which a crankshaft signal can be transmitted in unprocessed, amplified or conditioned form. The camshaft control units are designed to suppress forwarding of the crankshaft signal in a first state and to forward or to replicate the crankshaft signal and to send an additional signal in a second state. The disclosure also relates to a method for logically assigning the camshaft control units to the camshafts to be adjusted by them.

Abstract: Composite material units (CMU) of the structure (SE1-ML-LinkerL-Ligand2-SE2), are provided, wherein ML is a Mechanical Ligand, LinkerL is a chemical bond or entity that covalently links ML and Ligand2, Ligand2 is a chemical entity that is covalently linked to the structural entity SE2, or forms a mechanical bond with the structural entity SE2, and SE1 and SE2 are structural entities.

Abstract: A system for alignment of big bags prior to product filling. The system includes a first alignment arrangement configured to rotate an inflated big bag. The first alignment arrangement including a first drive configured to operate a first rotation part, a counter hold, and a displacement arrangement for displacing the first alignment arrangement and/or the counter hold relative to a big bag. The system may include a sensor arrangement configured to detect a rotational orientation of the inflated big bag and adapted to provide a sensor output based thereon, and a controller configured to receive the sensor output and control the first drive to rotate the inflated big bag based on the sensor output. A method of alignment of big bags prior to product filling, a computer program configured for executing acts of the method and a computer readable medium for storing the computer program.

Abstract: A system for treating kegs with data carriers. One or more treatment modules, each of which has a keg receiving area, a treatment head, and an one interface for a discharge line and for a cleaning medium line and/or at least one filling product line. A signaling device configured for signaling operations to be carried out with the treatment modules and/or a loading device for supplying and discharging the kegs to and from the treatment modules. A controller configured for controlling the treatment modules, the signaling device, and/or the feed device. A reading device connected to the controller for reading information from the data carriers. The controller being configured to control and/or regulate the treatment of the kegs, in particular a cleaning process and/or a filling process, in the treatment modules based on the information on the data carriers. The information being read by the reading device.

Abstract: A system for treating kegs with at least two treatment modules. Each treatment module has a keg receiving area, a treatment head, and an interface. The system contains a controller for controlling the treatment modules. At least one of the treatment modules is connected to a filling product source, which provides a first filling product, via the respective interface of the treatment module. At least one other treatment module of the treatment modules is connected to a filling product source, which provides a second filling product, via the respective interface of the treatment module. The controller is designed to actuate the treatment modules for a simultaneous and/or a delayed filling process for different filling products.

Abstract: A microphone having a multi-channel mixer and one or more connectors usable to receive and/or output audio. Any of the connectors may be used as an input connector, as an output connector, or configured to be switchable between being an input and an output connector. The user of the microphone may be able to conveniently use one or more of the connectors to expand the microphone to become part of a larger setup that uses multiple microphones. For example, an XLR connector of the microphone may be passive, and may be configured such that a user can daisy chain the output from an XLR connector of another microphone into an XLR connector of the microphone. In such an arrangement, an output based on one or both of the microphones may be output through another connector of the microphone, such as a USB connector.

Abstract: The invention relates to a treatment system for treating containers, in particular for treating kegs, each of which is preferably equipped with at least one keg fitting. The treatment system has at least one media supply for a product to be filled and/or for one or more treatment or cleaning media as well as at least one treatment station for receiving a container, in particular keg. The treatment station has at least one treatment head for cleaning the interior of and/or filling the container, in particular keg, and at least one supply interface via which the treatment station is connected to the media supply. According to the invention, at least one closure device for tightly closing the treatment head as well as at least one measuring and checking device for recording and checking process data are further provided in the treatment system for automatically checking installation and/or functioning of the treatment station.

Abstract: The present invention relates to a broadband microwave window assembly comprising a Brewster waveguide window, a single mode microwave reactor system comprising a waveguide with a Brewster waveguide window and a method to produce a waveguide with a Brewster waveguide window.

Abstract: The present invention relates to a single mode or single dominating mode microwave reactor, a single dominating mode microwave reactor system and a method of producing fuel, such as biofuel.

Abstract: Described herein are methods and systems for detecting electrical discharges that precede electrical fires in electrical wiring. One or more sensor devices coupled to a circuit detect one or more signal waveforms generated by electrical activity on the circuit. The sensor devices identify one or more transient signals within the one or more signal waveforms, and generate one or more transient characteristics based upon the identified transient signals. A server communicably coupled to the sensor devices receives the one or more transient characteristics. The server analyzes the one or more transient characteristics to identify one or more electrical discharge indications. The server generates one or more alert signals when one or more electrical discharge indications are identified.

Abstract: Methods and apparatuses for automatic analysis and optimization of an audio signal are described herein. An example method may comprise receiving, by an audio signal optimizer, a first indication to perform an audio signal optimization, receiving an audio signal from an input device, recording a sample of the audio signal, analyzing the sample of the audio signal for at least one audio parameter, and performing, based on an analysis of the sample of the audio signal, the audio signal optimization of the audio signal, wherein the audio signal optimization comprises a configuration of a gain level of the audio signal.

Abstract: A mixer includes a mixing chamber and a motor mechanically connected to the mixing chamber. The mixing chamber comprises a suspended elongate rigid tube section having a top end and an open bottom end, and a flexible tube section extending downwards from the open bottom end. The motor comprises a vibration motor mechanically coupled to the suspended elongate rigid tube section at the top end of the suspended elongate rigid tube section.

Abstract: A microphone may comprise a microphone element for detecting sound, and a digital signal processor configured to process a first audio signal that is based on the sound in accordance with a selected one of a plurality of digital signal processing (DSP) modes. Each of the DSP modes may be for processing the first audio signal in a different way. For example, the DSP modes may account for distance of the person speaking (e.g., near versus far) and/or desired tone (e.g., darker, neutral, or bright tone). At least some of the modes may have, for example, an automatic level control setting to provide a more consistent volume as the user changes their distance from the microphone or changes their speaking level, and that may be associated with particular default (and/or adjustable) values of the parameters attack, hold, decay, maximum gain, and/or target gain, each depending upon which DSP is being applied.

Abstract: A microphone may comprise a microphone element for detecting sound, and a digital signal processor configured to process a first audio signal that is based on the sound in accordance with a selected one of a plurality of digital signal processing (DSP) modes. Each of the DSP modes may be for processing the first audio signal in a different way. For example, the DSP modes may account for distance of the person speaking (e.g., near versus far) and/or desired tone (e.g., darker, neutral, or bright tone). At least some of the modes may have, for example, an automatic level control setting to provide a more consistent volume as the user changes their distance from the microphone or changes their speaking level, and that may be associated with particular default (and/or adjustable) values of the parameters attack, hold, decay, maximum gain, and/or target gain, each depending upon which DSP is being applied.

Abstract: A microphone having a multi-channel mixer and one or more connectors usable to receive and/or output audio. Any of the connectors may be used as an input connector, as an output connector, or configured to be switchable between being an input and an output connector. The user of the microphone may be able to conveniently use one or more of the connectors to expand the microphone to become part of a larger setup that uses multiple microphones. For example, an XLR connector of the microphone may be passive, and may be configured such that a user can daisy chain the output from an XLR connector of another microphone into an XLR connector of the microphone. In such an arrangement, an output based on one or both of the microphones may be output through another connector of the microphone, such as a USB connector.

Abstract: A microphone may comprise a microphone element for detecting sound, and a digital signal processor configured to process a first audio signal that is based on the sound in accordance with a selected one of a plurality of digital signal processing (DSP) modes. Each of the DSP modes may be for processing the first audio signal in a different way. For example, the DSP modes may account for distance of the person speaking (e.g., near versus far) and/or desired tone (e.g., darker, neutral, or bright tone). At least some of the modes may have, for example, an automatic level control setting to provide a more consistent volume as the user changes their distance from the microphone or changes their speaking level, and that may be associated with particular default (and/or adjustable) values of the parameters attack, hold, decay, maximum gain, and/or target gain, each depending upon which DSP is being applied.