Patents by Inventor Christian Rohlff

Christian Rohlff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of Alzheimer's disease
    Publication number: 20030064411
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of Alzheimer's disease, for monitoring the effectiveness of Alzheimer's disease treatment and for drug development. Alzheimer's disease-Associated Features (ADFs) detectable by two-dimensional electrophoresis of brain tissue are described. The invention further provides Alzheimer's disease-Associated Protein Isoforms (ADPIs) detectable in brain tissue, preparations comprising isolated ADPIs, antibodies specific for ADPIs and kits comprising the aforesaid.
    Type: Application
    Filed: December 10, 2001
    Publication date: April 3, 2003
    Inventors: Herath Mudiyanselage Athula Chandrasiri Herath, Rajesh Bhikhu Parekh, Christian Rohlff
  • Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression
    Publication number: 20030032773
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of BAD, for monitoring the effectiveness of BAD treatment, and for drug development. BAD-Associated Features (DFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides BAD-Associated Protein Isoforms (DPIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated DPIs, antibodies immunospecific for DPIs, and kits comprising the aforesaid.
    Type: Application
    Filed: February 23, 2001
    Publication date: February 13, 2003
    Inventors: Herath Mudiyanselage Athula Chandrasiri Herath, Rajesh Bhikhu Parekh, Christian Rohlff, Jonathan Alexander Terrett, Kerry Louise Tyson
  • Proteins, genes and their use for diagnosis and treatment of bipolar affective disorder (BAD) and unipolar depression
    Publication number: 20030032200
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of BAD, for monitoring the effectiveness of BAD treatment, and for drug development. BAD-Associated Features (DFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides BAD-Associated Protein Isoforms (DPIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated DPIs, antibodies immunospecific for DPIs, and kits comprising the aforesaid.
    Type: Application
    Filed: February 23, 2001
    Publication date: February 13, 2003
    Inventors: Herath Mudiyanselage Athula Chandrasiri Herath, Rajesh Bhikhu Parekh, Christian Rohlff
  • Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of alzheimer's disease
    Publication number: 20020164668
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of Alzheimer's disease, for monitoring the effectiveness of Alzheimer's disease treatment, and for drug development. Alzheimer's Disease-Associated Features (AFs), detectable by two-dimensional electrophoresis of cerebrospinal fluid, serum or plasma are described. The invention further provides Alzheimer's Disease-Associated Protein Isoforms (APIs) detectable in cerebrospinal fluid, serum or plasma, preparations comprising isolated APIs, antibodies, pharmaceutical compositions, diagnostic and therapeutic methods, and kits comprising or based on the same.
    Type: Application
    Filed: April 3, 2001
    Publication date: November 7, 2002
    Inventors: L. Kathryn Durham, David L. Friedman, Herath Mudiyanselage Athula Chandrasiri Herath, Lida H. Kimmel, Rajesh Bhikhu Parekh, David M. Potter, Christian Rohlff, B. Michael Silber, Thomas R. Stiger, P. Trey Sunderland, Robert Reid Townsend, W. Frost White, Stephen A. Williams