Patents by Inventor Christian S. SHERK

Christian S. SHERK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF A TYPE II PROTEIN ARGININE METHYLTRANSFERASE INHIBITOR AND AN ICOS BINDING PROTEIN TO TREAT CANCER
    Publication number: 20210267973
    Abstract: In one aspect, the present invention provides a method of treating cancer in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of a Type II protein arginine methyltransferase (Type II PRMT) inhibitor and administering to the human a therapeutically effective amount of an ICOS binding protein or antigen binding portion thereof. In another aspect, the present invention provides a Type II protein arginine methyltransferase (Type II PRMT) inhibitor and an ICOS binding protein or antigen binding fragment thereof for use in treating cancer in a human in need thereof.
    Type: Application
    Filed: May 24, 2019
    Publication date: September 2, 2021
    Inventors: Olena I. BARBASH, Andrew Mark FEDORIW, Susan KORENCHUK, Christian S. SHERK
  • COMBINED THERAPY WITH ICOS BINDING PROTEINS AND ARGININEMETHYLTRANSFERASE INHIBITORS
    Publication number: 20210260033
    Abstract: The present disclosure provides a method of treating cancer in a human in need thereof, the method comprising administering to the human a therapeutically effective amount of a Type I protein arginine methyltransferase (Type I PRMT) inhibitor and administering to the human a therapeutically effective amount of an ICOS (CD278), Inducible T-cell Costimulator) binding protein or antigen binding portion thereof.
    Type: Application
    Filed: May 24, 2019
    Publication date: August 26, 2021
    Inventors: Andrew Mark FEDORIW, Susan KORENCHUK, Helai MOHAMMAD, Christian S. SHERK