Patents by Inventor Christian Schickaneder
Christian Schickaneder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10526290Abstract: The present invention relates to bendamustine derivatives and related compounds of formula (VII), (VIII) and (IX), and medical uses thereof in particular in cancer therapy.Type: GrantFiled: June 14, 2013Date of Patent: January 7, 2020Assignee: SYNBIAS PHARMA AGInventors: Helmut Schickaneder, Christian Schickaneder, Armin Buschauer, Stefan Huber, Michael Limmert, Günther Bernhardt, Mathias Lubbe, Harald Hofmeier
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Patent number: 10442773Abstract: The present invention provides for amorphous Letermovir and orally administrable solid pharmaceutical formulations thereof (immediate release formulation). Said amorphous Letermovir is suitable for immediate release formulations when isolated out of an organic solution by either roller-drying said organic solution in a volatile organic solvent, in particular acetone, at a temperature of 30° C. to 60° C., and subsequently drying the amorphous Letermovir obtained, or isolating said amorphous Letermovir by precipitation from water miscible solvents selected from acetone or acetonitrile into excess water as anti-solvent, and subsequently filtrating or centrifuging the amorphous Letermovir obtained. The immediate release formulations of amorphous Letermovir are intended for use in methods of prophylaxis or methods of treatment of diseases associated with the group of Herpesviridae, preferably associated with cytomegalovirus (CMV), even more preferably associated with human cytomegalovirus (HCMV).Type: GrantFiled: June 19, 2014Date of Patent: October 15, 2019Assignee: AICURIS ANTI-INFECTIVE CURES GMBHInventors: Wilfried Schwab, Dirk Jung, Christian Schickaneder, Welljanne Martens, Michael Limmert, Clemens Bothe, Mathias Berwe, Nicole Rindermann
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Patent number: 10308665Abstract: The present invention relates to a method for the production of a rapamycin derivative of formula (I), the method comprising the preparation of a 2-(tri-substituted silyl)oxyethyl triflate by reacting ethylene oxide and a tri-substituted silyl triflate, reaction of the resulting 2-(tri-substituted silyl)oxyethyl triflate with rapamycin in the presence of a molar excess of organic base, and deprotection to obtain the rapamycin derivative of compound (I).Type: GrantFiled: June 22, 2016Date of Patent: June 4, 2019Assignee: Synbias Pharma AGInventors: Oleksandr Zabudkin, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
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Patent number: 10287254Abstract: The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl} acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses (FIG. 1).Type: GrantFiled: October 31, 2016Date of Patent: May 14, 2019Assignee: AiCuris GmbH & Co. KGInventors: Welljanne Maertens, Christian Schickaneder
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Publication number: 20190092792Abstract: The present invention is directed to crystalline vinorelbine monotartrate and its use for the prevention and treatment of cancer, particularly non-small cell lung cancer or breast cancer. The present invention also relates to a corresponding method for the manufacture of crystalline vinorelbine monotartrate.Type: ApplicationFiled: March 9, 2016Publication date: March 28, 2019Applicant: SYNBIAS PHARMA AGInventors: Oleksandr Zabudkin, Viktor Matviyenko, Vladimir Matha, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
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Publication number: 20190010168Abstract: The present invention relates to a method for the production of a rapamycin derivative of formula (I), the method comprising the preparation of a 2-(tri-substituted silyl)oxyethyl triflate by reacting ethylene oxide and a tri-substituted silyl triflate, reaction of the resulting 2-(tri-substituted silyl)oxyethyl triflate with rapamycin in the presence of a molar excess of organic base, and deprotection to obtain the rapamycin derivative of compound (I).Type: ApplicationFiled: June 22, 2016Publication date: January 10, 2019Inventors: Oleksandr Zabudkin, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
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Publication number: 20180201966Abstract: The present invention relates to a method for the stereo-selective production of pentostatin comprising an enzymatic transglycosylation reaction between 6,7-dihydroimidazo-[4,5-d]-[1,3]diazepin-8(3H)-one and a 2?-deoxyribonucleoside, followed by an ruthenium-catalyzed asymmetric transfer hydrogenation.Type: ApplicationFiled: July 6, 2016Publication date: July 19, 2018Inventors: Oleksandr Zabudkin, Christian Schickaneder, Iaroslav Matviienko, Volodymyr Sypchenko
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Publication number: 20170362186Abstract: The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl} acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses.Type: ApplicationFiled: July 3, 2017Publication date: December 21, 2017Applicant: AiCuris GmbH & Co. KGInventors: Welljanne MAERTENS, Christian SCHICKANEDER
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Publication number: 20170114026Abstract: The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl}acetic acid and solvates thereof, to the use thereof in a method of treating find/or preventing virus infections, find to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses (FIG. 1).Type: ApplicationFiled: October 31, 2016Publication date: April 27, 2017Applicant: AiCuris GmbH & Co. KGInventors: Welljanne MAERTENS, Christian SCHICKANEDER
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Patent number: 9512085Abstract: The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl}acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses.Type: GrantFiled: February 28, 2013Date of Patent: December 6, 2016Assignee: AICURIS GMBH & CO. KGInventors: Welljanne Maertens, Christian Schickaneder
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Patent number: 9447120Abstract: The invention relates to the production of zinc trisodium pentetic acid (Zn-DTPA) and to new crystalline forms of said salt.Type: GrantFiled: May 23, 2014Date of Patent: September 20, 2016Assignee: Hameln Pharma Plus GmbHInventors: Christian Schickaneder, Vendel Smahovský, Pavol Valachovic, Mathias Dewald, Pavel Hradil, Janka Králová, Radek Melnický, Petr Slézar, Ivan Kakalik
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Publication number: 20160185793Abstract: The present invention provides a new method of separating epothilones from one another that can be used on an industrial scale for the selective enrichment of epothilone and to provide a crystalline solid of enhanced purity, which can be used for the production of pharmaceutical preparations without using normal or reverse-phase chromatography or any energy input via distillation apparatus, wherein the new method comprises the steps: a. dissolving a crude containing epothilones in an alkyl ester, b. cooling the solution form a slurry, c. isolating a crystalline solid from the slurry.Type: ApplicationFiled: August 18, 2014Publication date: June 30, 2016Inventors: Mathias LUBBE, Christian SCHICKANEDER, Michael LIMMERT
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Publication number: 20160145216Abstract: The present invention provides for amorphous Letermovir and orally administrable solid pharmaceutical formulations thereof (immediate release formulation). Said amorphous Letermovir is suitable for immediate release formulations when isolated out of an organic solution by either roller-drying said organic solution in a volatile organic solvent, in particular acetone, at a temperature of 30° C. to 60° C., and subsequently drying the amorphous Letermovir obtained, or isolating said amorphous Letermovir by precipitation from water miscible solvents selected from acetone or acetonitrile into excess water as anti-solvent, and subsequently filtrating or centrifuging the amorphous Letermovir obtained. The immediate release formulations of amorphous Letermovir are intended for use in methods of prophylaxis or methods of treatment of diseases associated with the group of Herpesviridae, preferably associated with cytomegalovirus (CMV), even more preferably associated with human cytomegalovirus (HCMV).Type: ApplicationFiled: June 19, 2014Publication date: May 26, 2016Applicant: AICURIS ANTI-INFECTIVE CURES GMBHInventors: Wilfried SCHWAB, Dirk JUNG, Christian SCHICKANEDER, Welljanne MARTENS, Michael LIMMERT, Clemens BOTHE, Mathias BERWE, Nicole RINDERMANN
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Publication number: 20160130283Abstract: The invention relates to the production of zinc trisodium pentetic acid (Zn-DTPA) and to new crystalline forms of said salt.Type: ApplicationFiled: May 23, 2014Publication date: May 12, 2016Inventor: Christian Schickaneder
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Publication number: 20150152066Abstract: The present invention relates to bendamustine derivatives and related compounds of formula (VII), (VIII) and (IX), and medical uses thereof in particular in cancer therapy.Type: ApplicationFiled: June 14, 2013Publication date: June 4, 2015Applicant: Helmut SchickanederInventors: Helmut Schickaneder, Christian Schickaneder, Armin Buschauer, Stefan Huber, Michael Limmert, Günther Bernhardt, Mathias Lubbe, Harald Hofmeier
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Publication number: 20150045371Abstract: The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl}acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses.Type: ApplicationFiled: February 28, 2013Publication date: February 12, 2015Applicant: AiCuris GmbH & Co. KGInventors: Welljanne Maertens, Christian Schickaneder
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Patent number: 8809549Abstract: The present invention relates to particular esters of bendamustine and related compounds, and medical uses thereof.Type: GrantFiled: April 25, 2013Date of Patent: August 19, 2014Inventors: Helmut Schickaneder, Armin Buschauer, Guenther Bernhardt, Christian Schickaneder, Michael Limmert, Stefan Huber
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Publication number: 20130289032Abstract: The present invention relates to particular esters of bendamustine and related compounds, and medical uses thereof.Type: ApplicationFiled: April 25, 2013Publication date: October 31, 2013Inventors: Helmut SCHICKANEDER, Armin Buschauer, Guenther Bernhardt, Christian Schickaneder, Michael Limmert, Stefan Huber
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Patent number: RE49897Abstract: The invention relates to besylate and tosylate salts of {8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl} acetic acid and solvates thereof, to the use thereof in a method of treating and/or preventing virus infections, and to the use thereof to produce drugs for use in treating and/or preventing diseases, in particular use as antiviral agents, in particular against cytomegaloviruses (FIG. 1).Type: GrantFiled: May 14, 2021Date of Patent: April 2, 2024Assignee: AIC246 AG & Co. KGInventors: Welljanne Maertens, Christian Schickaneder