Patents by Inventor Christian Schnider

Christian Schnider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190352312
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 21, 2019
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • Patent number: 10414780
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: September 17, 2019
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • Patent number: 10246409
    Abstract: The invention relates to a method for the preparation of bis(fluorosulfonyl)-imide and its derivatives at elevated temperature.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: April 2, 2019
    Assignee: Lonza Ltd
    Inventors: Christian Schnider, Anna-Christina Hormes, Andreas Klein, Michael Bersier, Philipp Studer, Stefan Tille, Thomas Gruetzner
  • Publication number: 20180362343
    Abstract: The invention relates to a method for the preparation of bis(fluorosulfonyl)-imide, the method starts from bis(chlorosulfonyl)-imide or its respective derivatives, which is reacted with HF in the presence of chlorosulfonyl isocyanate, and uses a certain extraction step for extraction of bis(fluorosulfonyl)-imide from an aqueous solution; the invention is also useful for the preparation of certain salts of bis(fluorosulfonyl)-imide and its derivatives.
    Type: Application
    Filed: October 26, 2016
    Publication date: December 20, 2018
    Inventors: Anna-Christina HORMES, Andreas KLEIN, Christian SCHNIDER, Thomas GRUETZNER, Michael BERSIER, Philipp STUDER, Stefan TILLE, Desirée LORENZ, Hilke-Marie LORENZ, Hans HASSE, Erik VON HARBOU, Johannes NEUHAUS
  • Patent number: 10125087
    Abstract: The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNO2 in a continuous way, in which the n-butanol, an acid and NaNO2 are mixed in a mixing device which provides for a pressure drop of at least 1 bar; the acid is selected from the group consisting of HCI, H2SO4, formic acid, methanesulfonic acid, and mixtures thereof; and the amount of HCI is at least 1.02 molar equivalent based on the molar amount of n-butanol.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: November 13, 2018
    Assignee: LONZA LTD
    Inventors: Christoph Taeschler, Ulrich Mayerhoeffer, Christophe Girard, Michael Bittel, Rolf Kalbermatten, Claudio Arnold, Stefan Garms, Christian Schnider, Stefan Tille, Manuel Favre, Guy Raboud, Kilian Schnydrig, Martin Venetz, Thomas Eggel
  • Publication number: 20180312528
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: July 6, 2018
    Publication date: November 1, 2018
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • Publication number: 20180251420
    Abstract: The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an acid and NaNO2 in a continuous way, in which the n-butanol, an acid and NaNO2 are mixed in a mixing device which provides for a pressure drop of at least 1 bar; the acid is selected from the group consisting of HCI, H2SO4, formic acid, methanesulfonic acid, and mixtures thereof; and the amount of HCI is at least 1.02 molar equivalent based on the molar amount of n-butanol.
    Type: Application
    Filed: September 14, 2016
    Publication date: September 6, 2018
    Inventors: Christoph Taeschler, Ulrich Mayerhoeffer, Christophe Girard, Michael Bittel, Rolf Kalbermatten, Claudio Arnold, Stefan Garms, Christian Schnider, Stefan Tille, Manuel Favre, Guy Raboud, Kilian Schnydrig, Martin Venetz, Thomas Eggel
  • Patent number: 10047102
    Abstract: The present invention provides a compound of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: August 14, 2018
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • Publication number: 20180194779
    Abstract: The present invention provides a compound of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: July 21, 2015
    Publication date: July 12, 2018
    Inventors: Bjoern Bartels, Cosimo Dolente, Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Ulrike Obst Sander, Jens-Uwe Peters, Mark Rogers-Evans, Thomas Woltering, Christian Schnider, Roger Wermuth
  • Publication number: 20180141901
    Abstract: The invention relates to a method for the preparation of bis(fluorosulfonyl)-imide and its derivatives at elevated temperature.
    Type: Application
    Filed: May 4, 2016
    Publication date: May 24, 2018
    Inventors: Christian Schnider, Anna-Christina Hormes, Andreas Klein, Michael Bersier, Philipp Studer, Stefan Tille, Thomas Gruetzner
  • Patent number: 9605006
    Abstract: The present invention provides a compound of formula I? having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: March 28, 2017
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Jens-Uwe Peters, Ulrike Obst Sander, Christian Schnider, Roger Wermuth, Thomas Woltering
  • Patent number: 9546136
    Abstract: The invention relates to a method for the preparation of imidodisulfuryl compounds in a continuous reaction at elevated temperatures.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: January 17, 2017
    Assignee: Lonza Ltd
    Inventors: Christian Schnider, Dominique Roberge, Michael Gottsponer, Andreas Klein, Thomas Gruetzner, Michael Bittel, Stefan Tille, Anna-Christina Hormes, Janine Leiggener
  • Publication number: 20160318952
    Abstract: The present invention provides a compound of formula I? having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: December 17, 2014
    Publication date: November 3, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Wolfgang Guba, Wolfgang Haap, Andreas Kuglstatter, Jens-Uwe Peters, Ulrike Obst Sander, Christian Schnider, Roger Wermuth, Thomas Woltering
  • Publication number: 20160289177
    Abstract: The invention relates to a method for the preparation of imidodisulfuryl compounds in a continuous reaction at elevated temperatures.
    Type: Application
    Filed: July 10, 2014
    Publication date: October 6, 2016
    Inventors: Christian Schnider, Dominique Roberge, Michael Gottsponer, Andreas Klein, Thomas Gruetzner, Michael Bittel, Stefan Tille, Anna-Christina Hormes, Janine Leiggener
  • Publication number: 20160052920
    Abstract: The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
    Type: Application
    Filed: April 8, 2014
    Publication date: February 25, 2016
    Applicants: HOFFMANN-LA ROCHE INC., SIENA BIOTECH S.p.A.
    Inventors: Hans Hilpert, Roland Humm, Thorsten Muser, Christian Schnider, Roger Wermuth, Thomas Woltering
  • Patent number: 8324418
    Abstract: Organic dithiopyrophosphates of formula wherein R1, R2, R3, R4 and R5 independently are hydrogen, C1-4 alkyl, chloromethyl or bromomethyl, are prepared in a two-step process from the corresponding 1,3-diols and thiophosphoryl chloride, using 3-methylpyridine both as solvent and as base.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: December 4, 2012
    Assignee: Lonza Ltd.
    Inventors: Gesa Paradies, Thomas Riedel, Christian Schnider
  • Publication number: 20110207955
    Abstract: Organic dithiopyrophosphates of formula wherein R1, R2, R3, R4 and R5 independently are hydrogen, C1-4 alkyl, chloromethyl or bromomethyl, are prepared in a two-step process from the corresponding 1,3-diols and thiophosphoryl chloride, using 3-methylpyridine both as solvent and as base.
    Type: Application
    Filed: October 21, 2009
    Publication date: August 25, 2011
    Applicant: LONZA LTD.
    Inventors: Gesa Paradies, Thomas Riedel, Christian Schnider