Abstract: An injection device for dispensing a dose of a substance, the device including a housing, a dispensing element which can be displaced relative to the housing and a locking element which can be coupled with the dispensing element during or after a substance dispensing operation so that after the dispensing element has effected a dispensing operation once, it can no longer be operated to dispense another dose, and a method of locking an injection device after a substance has been dispensed once, whereby a dispensing element operated to dispense the substance is locked or blocked before, during or after dispensing a set dose so that no more substance can be dispensed.

Abstract: An injection device including an accommodating device for a substance to be delivered, e.g. a vial or ampoule holder, which is insertable into and can be displaced relative to the injection device or a part thereof; an adjusting element for adjusting a dose to be administered from the injection device, which element is inserted in the injection device; and a coupling element for coupling the accommodating device to the adjusting element so that the adjusting element is at least partially moved out from the injection device when the accommodating device is inserted. A method for preparing an injection device using a dual chamber vial or ampoule to administer a substance, wherein the method involves using an adjusting device which is released, extended or pushed out from the injection device not before or after the substance to be administered from dual chamber vial or ampoule is mixed.

Abstract: A threaded rod for an injection device, wherein the rod includes a thread on an external surface, the thread supporting or carrying, at least partially, engaging elements and/or teeth. In one embodiment, the present invention encompasses a dosing mechanism for an injection device, including a rotational defining element which enables a threaded rod to be rotated in one direction, rotation being blocked or prevented in the counter direction by at least one blocking element which co-operates with a thread of the threaded rod, wherein the thread carries, supports or has associated teeth and/or engaging elements. In one embodiment, the present invention encompasses an injection device including at least one engaging element which co-operates with a blocking element associated with a threaded rod, whereby the threaded rod is rotatable in one direction in relation to the injection device, rotation in the opposite direction being prevented.

Abstract: A dosing device for an injection device, including a dosing element moveable or rotatable in a first direction to select a dose and a guiding element for guiding a component of the injection device, the dosing element being moved or rotated relative to the guiding element to select a dose, wherein the guiding element is rotated or moved along with the dosing element when the dosing element is moved or rotated against the first direction to adjust the selected dose. A method of adjusting a dose selected by a dosing device is encompassed, the method including selecting a dose by moving or rotating a dosing element relative to a guiding element which is moved or rotated along with the dosing element during the selecting and adjusting the selected dose by moving or rotating the dosing element in the opposite direction.

Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.

Abstract: A dose metering mechanism for setting a dose to be administered from an injection device, the mechanism including a setting sleeve marked with dose amounts by which a dose to be administered is set by rotation, and a rotating sleeve which can be rotated out of the dose metering mechanism to prime the dispensing of a dose and is marked with dose amounts, the setting sleeve coupled to the rotating sleeve whereby when the rotating sleeve is fully rotated out, the dose amount of the setting sleeve is not offset from an associated dose amount of the rotating sleeve.

Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.

Abstract: A device for administering an injectable product including a housing with a reservoir for the product, a delivery device, which can be displaced out of a release position and into an activating position and, from the activating position, executes a delivery movement via which a set product dose is discharged from the reservoir, and a dosing device that, for setting a product dose, can execute a dosing movement in dosing positions predetermined by detent engagement when the delivery device occupies the release position, wherein the delivery device, when in the activating position and when moving into the activating position, is coupled to the dosing device via a blocking engagement which prevents the dosing device in the respectively set dosing position from executing dosing movements.

Abstract: A dosing mechanism for use with an injection device to adjust a dose to be discharged from the injection device, the dosing mechanism including an adjusting element which can be moved relative to the dosing mechanism and including a coupling element for being releaseably coupled to a threaded bar associated with the injection device such that the adjusting element can be moved relative to the bar in one direction while a relative movement in the opposite direction is prevented, the dosing mechanism further including a retaining element with an engaging element for preventing the bar from being rotated in at least one direction, and a releasing element for uncoupling the adjusting element and bar.

Abstract: A lock for an injection device including a threaded rod, wherein the lock includes one of an anti-rotation or claw-type securing element engageable in cooperative anti-rotation elements or claws of the injection device to prevent rotation of the threaded rod relative to the injection device.

Abstract: An injection device with a housing and an operating element or coupling element mounted in the housing in such a way that the operating element or coupling element may be retained in a first position by a first holding connection and may be displaced into a second position that is axially offset relative to the first position after introducing an ampoule. In some embodiments, the operating element or coupling element may be retained by a second holding connection in the second position.

Abstract: A lock for a dosing mechanism of an injection device, the lock including at least one holding element that interacts with the dosing mechanism, or with a dosing element of the dosing mechanism, whereby an adjustment movement of the dosing mechanism or the dosing element is prevented in a starting position of the lock and is possible only after a movement or displacement of the lock or the holding element. An injection device used in conjunction with a two-chamber ampoule is encompassed, as is a method for preparing the injection device for dispensing a substance wherein the ampoule is introduced into the injection device and a lock is released when the ampoule has been introduced far enough to appropriately mix the substances in the two chambers, whereupon the mixed substances can be dispensed from the ampoule.

Abstract: An injection device including an accommodating device for a substance to be delivered, e.g. a vial or ampoule holder, which is insertable into and can be displaced relative to the injection device or a part thereof; an adjusting element for adjusting a dose to be administered from the injection device, which element is inserted in the injection device; and a coupling element for coupling the accommodating device to the adjusting element so that the adjusting element is at least partially moved out from the injection device when the accommodating device is inserted. A method for preparing an injection device using a dual chamber vial or ampoule to administer a substance, wherein the method involves using an adjusting device which is released, extended or pushed out from the injection device not before or after the substance to be administered from dual chamber vial or ampoule is mixed.

Abstract: An injection device including a pusher, a dosing element and a coupling element, the pusher being displaceable in an injection direction and having at least one holding or detent area, e.g. a toothed area, for detachably holding the pusher relative to the injection device, wherein the coupling element positions the pusher relative to the dosing element for fixing the axial position of the pusher relative to the dosing element.

Abstract: A setting mechanism for setting or selecting a quantity of a substance to be dispensed from an injection device, the mechanism including a dose setting element and an adjusting element which can be operated by a user, wherein the adjusting element is operably coupled to the dose setting element and an overstrain lock is provided between the dose setting element and the adjusting element.

Abstract: A threaded rod for an injection device, wherein the rod includes a thread on an external surface, the thread supporting or carrying, at least partially, engaging elements and/or teeth. In one embodiment, the present invention encompasses a dosing mechanism for an injection device, including a rotational defining element which enables a threaded rod to be rotated in one direction, rotation being blocked or prevented in the counter direction by at least one blocking element which co-operates with a thread of the threaded rod, wherein the thread carries, supports or has associated teeth and/or engaging elements. In one embodiment, the present invention encompasses an injection device including at least one engaging element which co-operates with a blocking element associated with a threaded rod, whereby the threaded rod is rotatable in one direction in relation to the injection device, rotation in the opposite direction being prevented.

Abstract: A dosing device for setting a dose to be delivered by an injection device, the dosing device including a setting element, e.g. a setting sleeve, and a drawing element, e.g. a rotating sleeve, which can be rotated out of the dosing device for preparing a dose delivery. A stop is on the setting element, and a counter stop is on the drawing element so that a rotational motion of the drawing element relative the setting element can be limited by the stops. The present invention encompasses a method for setting a dose that should be delivered by an injection device, wherein the dose to be delivered can be set by a setting element, e.g. a setting sleeve, and a drawing element of the injection device, e.g. a rotating sleeve, can subsequently draw up the dose by effecting a rotational motion to deliver the set dose from the injection device in a subsequent step. According to the present invention, the setting process is isolated from drawing process.

Abstract: An adjusting device, and method, used to adjust a dose of a substance to be administered by an injection device, wherein the adjusting device includes a first element and at least one additional element displaceable relative to the first element, the first element having at least two thread pitches which are offset in relation to each other such that at least one thread element of the at least one additional element is only guided into one of the at least two thread pitches of the first element. The invention encompasses a method for making an adjusting device for an injection device, wherein the thread of at least one dosing element is introduced into an associated thread of an additional dosing element, such that a predetermined position ratio between the dosing element and the additional dosing element is established.

Abstract: An injection device for injecting a substance from an ampoule inserted in the device, the device including one or more of the following components: an internal thread for engaging a threaded rod, the internal thread including several contact faces enabling the use of a different threaded rods, a real-time display for displaying a quantity of a substance, e.g., the quantity to be injected or dispensed, the quantity available for dispensing or the quantity dispensed, a mechanical lock for locking the device prior to inserting the ampoule, and a claw lock for preventing use of the injection device.

Abstract: An injection device for dispensing a dose of a substance, the device including a housing, a dispensing element which can be displaced relative to the housing and a locking element which can be coupled with the dispensing element during or after a substance dispensing operation so that after the dispensing element has effected a dispensing operation once, it can no longer be operated to dispense another dose, and a method of locking an injection device after a substance has been dispensed once, whereby a dispensing element operated to dispense the substance is locked or blocked before, during or after dispensing a set dose so that no more substance can be dispensed.