Abstract: The present invention relates to the use of poloxamers as cell culture media additives. The poloxamers are suitable for foam reduction as well as for shear protection.

Abstract: The present invention relates to a device and processes for producing liquid media for cell cultures, whereby the liquid media are produced automatically by dissolving ingredients in water. The present invention also relates to a device for producing media used in cell cultures or a substance produced by cell cultures using a bioreactor process.

Abstract: A brewing module for preparing a brewed drink from a portion capsule, includes a first brewing module part and a second brewing module part, which is movable relative to a housing between a first brewing module part position and a second brewing module part position. An operating element is able to be brought manually from a first into a second operating element position, from which a movement is transmitted via a transmission mechanism into a movement of the second brewing module part. The transmission mechanism includes a cam disc that is rotatably mounted on the housing by the operating element wherein the second brewing module part is displaceable along a displacement stretch, which is fixed with respect to the housing, from a first brewing module part position into the second brewing module part position by way of the cam disc being rotated by the operating element.

Abstract: An apparatus for dosing coffee beans for the purpose of selecting a metered quantity to be ground comprises a portioning device with a metering chamber having a receiving volume for receiving the coffee beans. The receiving volume is variable. Preferably, the setting of the metered quantity is performed mechanically, wherein the effect of the settings on the portioning device takes place mechanically.

Abstract: A unit of a coffee apparatus, in particular a coffee machine for brewing a coffee drink, includes a coffee bean container for storing the coffee beans, a portioner for portioning the coffee beans for an individual portion, and a grinder for grinding the portioned coffee beans. The coffee bean container and the portioner are formed in a common container module. The unit has a module receptacle, by which the container module can be connected during use and removed after use, and the container module has settings for a portion amount and a degree of grinding, which can be selected by the user. The portion amount setting influences the portioner and the degree of grinding setting influences the grinder. A simple, cost-effective and easy-to-use information exchange module between coffee container and coffee apparatus is thereby created.

Abstract: The present invention relates to methods and systems for performing perfusion cell culture whereby the supernatant of the bleed stream is recovered.

Abstract: A method for executing and translating a computer program in a computer network, in particular for controlling a microscope, wherein in the case of at least one function call to the relevant second function, multiple return values from multiple preceding function calls are transferred as separate parameters. This allows significantly more complex and flexible function calls. More flexibility in the execution of container-based functions of a computer program in a computer network can additionally be achieved in that the computer program has not only function calls but also instructions for controlling the program flow, for example instructions for the conditional execution of program sections and jump instructions. The development of container-based computer programs can be simplified and speeded up by providing a database that contains the execution requirements of the function modules and also the interface definitions thereof. This permits a static typing of variables.

Abstract: A brewing module for preparing a brewed drink from a portion capsule, includes a first brewing module part and a second brewing module part, which is movable relative to the housing between a first brewing module part position and a second brewing module part position, wherein a brewing chamber is formed in the second brewing module part position. Furthermore, an operating element is able to be brought manually from a first into a second operating element position, from which a movement is transmitted via a transmission mechanism into a movement of the second brewing module part. The brewing module further includes a damping device for damping the movement of the second brewing module part. This damping device is designed such that it has non-constant damping characteristics as a function of the position and/or as a function of the movement direction.

Abstract: A method for executing and translating a computer program in a computer network, in particular for controlling a microscope, wherein in the case of at least one function call to the relevant second function, multiple return values from multiple preceding function calls are transferred as separate parameters. This allows significantly more complex and flexible function calls. More flexibility in the execution of container-based functions of a computer program in a computer network can additionally be achieved in that the computer program has not only function calls but also instructions for controlling the program flow, for example instructions for the conditional execution of program sections and jump instructions. The development of container-based computer programs can be simplified and speeded up by providing a database that contains the execution requirements of the function modules and also the interface definitions thereof. This permits a static typing of variables.

Abstract: A unit of a coffee apparatus, in particular a coffee machine for brewing a coffee drink, includes a coffee bean container for storing the coffee beans, a portioner for portioning the coffee beans for an individual portion, and a grinder for grinding the portioned coffee beans. The coffee bean container and the portioner are formed in a common container module. The unit has a module receptacle, by which the container module can be connected during use and removed after use, and the container module has settings for a portion amount and a degree of grinding, which can be selected by the user. The portion amount setting influences the portioner and the degree of grinding setting influences the grinder. A simple, cost-effective and easy-to-use information exchange module between coffee container and coffee apparatus is thereby created.

Abstract: An actuator includes a housing, a first nut in the housing, a second nut in the housing, and a threaded spindle screwed into the first nut and the second nut. The first nut exerts a first force in a first direction on the threaded spindle, and the second nut exerts a second force in a second direction on the threaded spindle, the first direction being different than the second direction.

Abstract: A brewing module for preparing a brewed drink from a portion capsule, includes a first brewing module part and a second brewing module part, which is movable relative to a housing between a first brewing module part position and a second brewing module part position. An operating element is able to be brought manually from a first into a second operating element position, from which a movement is transmitted via a transmission mechanism into a movement of the second brewing module part. The transmission mechanism includes a cam disc that is rotatably mounted on the housing by the operating element wherein the second brewing module part is displaceable along a displacement stretch, which is fixed with respect to the housing, from a first brewing module part position into the second brewing module part position by way of the cam disc being rotated by the operating element.

Abstract: A brewing module for preparing a brewed drink from a portion capsule, includes a first brewing module part and a second brewing module part, which is movable relative to the housing between a first brewing module part position and a second brewing module part position, wherein a brewing chamber is formed in the second brewing module part position. Furthermore, an operating element is able to be brought manually from a first into a second operating element position, from which a movement is transmitted via a transmission mechanism into a movement of the second brewing module part. The brewing module further includes a damping device for damping the movement of the second brewing module part. This damping device is designed such that it has non-constant damping characteristics as a function of the position and/or as a function of the movement direction.

Abstract: An actuator includes a housing, a first nut in the housing, a second nut in the housing, and a threaded spindle screwed into the first nut and the second nut. The first nut exerts a first force in a first direction on the threaded spindle, and the second nut exerts a second force in a second direction on the threaded spindle, the first direction being different than the second direction.

Abstract: The invention relates to an application unit for an application device, in particular an application gun for applying gel-like and/or paste-like compositions, having an output unit for dispensing the compositions, a connection element, such as a cover, for connecting the output unit to the main body of the application device, and a closure element, wherein the closure element is rotatable around an axis of rotation with respect to the connection element and the output unit for fastening the output unit on the connection element and for detaching the output unit from the connection element, wherein a lifting unit is formed and arranged in such a way that the output unit is lifted by a rotation of the closure element.

Abstract: An application device for materials, in particular adhesives, including at least one cartridge receiving device for receiving a replaceable cartridge which contains a material and has a material outlet opening; a rotary device for metering or mixing the material, rotary device having a first engagement element; a drive device for driving the rotary device, the drive device having a rod which is mounted in a rotatable and axially movable manner and has a second engagement element at the end face; and a gearing unit for driving the rod in order to bring the first and the second engagement element into engagement with each other.

Abstract: A driving device of a metering and mixing apparatus for multi-component substances is disclosed, which driving device can have at least two cartridge holders for holding interchangeable cartridges with individual substance components, a discharging apparatus for simultaneously discharging the substance components from the cartridges through component outlets with the aid of discharging pistons entering the cartridge holder or cartridges, and a mixing apparatus which is connected to the component outlets, for mixing the discharged substance components and discharging the latter in mixed form, and a transmission unit for the connection of a drive motor, wherein the transmission unit can have a detector for detecting at least one counter pressure which builds up during the discharging of at least one of the substance components, and a controller, which is connected on an inlet side to the detector for bringing about a driving control function in response to a detection result.

Abstract: A drive apparatus of a metering and mixing device is provided for multi-component materials, for example, for multi-component adhesives. The metering and mixing device can have at least two cartridge-accommodating devices for accommodating replaceable cartridges having individual material components, and a discharging device for simultaneously discharging the material components from the cartridges through the component outlets by discharging plungers that plunge into the cartridge-accommodating device and a mixing device. A transmission unit connects a drive machine, and has a coupling for forced connection of a discharge of at least two material components by correspondingly synchronized actuation of discharging plungers by respective discharging rods.