Patents by Inventor Christian Selle

Christian Selle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220031673
    Abstract: The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
    Type: Application
    Filed: August 11, 2021
    Publication date: February 3, 2022
    Inventors: Christian Sell, Timothy Nacarelli, Ashley Azar
  • Publication number: 20210379026
    Abstract: The present invention includes methods and compositions for preventing, ameliorating, and treating certain skin disorders caused due to UV-induced, age-related, and post-inflammatory cutaneous changes. The skin disorders include, in non-limiting examples, static wrinkles, fine wrinkles, loss of skin tone, ephelides, melasma, senile purpura, UV-damage to the skin, static rhytides, prominent hand veins, field cancerization of epithelium such as in squamous cell carcinoma in situ, keloids, and imbalance in ratio of collagen isoforms. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a rapamycin and a dermatologically acceptable carrier.
    Type: Application
    Filed: October 10, 2019
    Publication date: December 9, 2021
    Inventors: Christina L. Chung, Christian Sell, Ibiyonu O. Lawrence
  • Patent number: 11179374
    Abstract: The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: November 23, 2021
    Assignee: Drexel University
    Inventors: Christian Sell, Timothy Nacarelli, Ashley Azar
  • Publication number: 20200281903
    Abstract: The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
    Type: Application
    Filed: May 21, 2020
    Publication date: September 10, 2020
    Inventors: Christian Sell, Timothy Nacarelli, Ashley Azar
  • Patent number: 10695326
    Abstract: The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: June 30, 2020
    Assignee: Drexel University
    Inventors: Christian Sell, Timothy Nacarelli, Ashley Azar
  • Publication number: 20180280362
    Abstract: The present invention includes compositions and methods for treating or preventing certain dermal disorders including dermal atrophy, pseudoscars, actinic keratosis, seborrheic or actinic keratoses, lentigines, focal areas of dermal thickening, and coarse wrinkles. In certain embodiments, the compositions useful within the invention comprise a therapeutically effective amount of a mTORC1 inhibitor and a dermatologically acceptable carrier.
    Type: Application
    Filed: September 19, 2016
    Publication date: October 4, 2018
    Inventors: Christian SELL, Timothy NACARELLI, Ashley AZAR
  • Publication number: 20180142189
    Abstract: The presently disclosed subject matter is directed to acidic disinfecting and/or cleaning compositions that comprise an acid, a solvent, a nonionic surfactant and optionally one or more additives. The disclosed compositions can be used to clean and/or disinfect a wide variety of products (such as bottles) in the food, dairy, beverage, brewery, and soft drink industries.
    Type: Application
    Filed: April 29, 2016
    Publication date: May 24, 2018
    Inventors: Nathalie Catherine Gerard, Walter John Watkinson, Petr Basar, Christian Selle
  • Publication number: 20090208316
    Abstract: An apparatus and a method are proposed for removing a covering film from a container. The apparatus has at least one gripping apparatus and a mechanism for producing a predetermined breaking point on a container. After production of the predetermined breaking point, the gripping apparatus grips a gripping face which is delimited by the predetermined breaking point, for removing the covering film from the container, and separates the gripping face during the removal of the covering film from the container.
    Type: Application
    Filed: January 3, 2007
    Publication date: August 20, 2009
    Inventors: Werner Mayer, Ulrich Krauss, Jochen Peters, Christian Selle, Klaus Ullherr
  • Patent number: 6340674
    Abstract: A method of inhibiting the proliferation and causing the differentiation of undifferentiated cells comprising contacting the undifferentiated cells with an effective amount of an antisense oligonucleotide having a sequence which is complementary to a region of the IGF-1 receptor RNA. The sequence of the antisense oligonucleotide is selected from an oligodeoxynucleotide sequence complementary to codons −29 to −24 of the signal sequence of the IGF-1 receptor and an oligoribodeoxynucleotide sequence complementary to codons 1 to 309 of the sequence of the IGF-1 receptor. The oligoribonucleotide sequence may be provided by an expression vector.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: January 22, 2002
    Assignee: Thomas Jefferson University
    Inventors: Renato Baserga, Christian Sell, Raphael Rubin
  • Patent number: 6331526
    Abstract: A method of inhibiting the proliferation and causing the differentiation of undifferentiated cells comprising contacting the undifferentiated cells with an effective amount of an antisense oligonucleotide having a sequence which is complementary to a region of the IGF-1 receptor RNA. The sequence of the antisense oligonucleotide is selected from an oligodeoxynucleotide sequence complementary to codons −29 to −24 of the signal sequence of the IGF-1 receptor and an oligoribonucleotide sequence complementary to codons 1 to 309 of the sequence of the IGF-1 receptor. The oligoribonucleotide sequence may be provided by an expression vector.
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: December 18, 2001
    Assignee: Thomas Jefferson University
    Inventors: Renato Baserga, Christian Sell, Raphael Rubin
  • Patent number: 6274562
    Abstract: A method of inhibiting the proliferation and causing the differentiation of undifferentiated cells comprising contacting the undifferentiated cells with an effective amount of an antisense oligonucleotide having a sequence which is complementary to a region of the IGF-1 receptor RNA. The sequence of the antisense oligonucleotide is selected from an oligodeoxynucleotide sequence complementary to codons −29 to −24 of the signal sequence of the IGF-1 receptor and an oligoribodeoxynucleotide sequence complementary to codons 1 to 309 of the sequence of the IGF-1 receptor. The oligoribodeoxynucleotide sequence may be provided by an expression vector.
    Type: Grant
    Filed: June 20, 1997
    Date of Patent: August 14, 2001
    Assignee: Thomas Jefferson University
    Inventors: Renato Baserga, Christian Sell, Raphael Rubin
  • Patent number: 5643788
    Abstract: A method of inhibiting the proliferation and causing the differentiation of undifferentiated cells comprising contacting the undifferentiated cells with an effective amount of an antisense oligonucleotide having a sequence which is complementary to a region of the IGF-1 receptor RNA. The sequence of the antisense oligonucleotide is selected from an oligodeoxynucleotide sequence complementary to codons -29 to -24 of the signal sequence of the IGF-1 receptor and an oligoribonucleotide sequence complementary to codons 1 to 309 of the sequence of the IGF-1 receptor. The oligoribonucleotide sequence may be provided by an expression vector.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 1, 1997
    Assignee: Thomas Jefferson University
    Inventors: Renato Baserga, Christian Sell, Raphael Rubin