Patents by Inventor Christian Siebel

Christian Siebel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Notch pathway inhibition
    Patent number: 9914774
    Abstract: The invention provides Notch pathway inhibition with reduced toxicity.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: March 13, 2018
    Assignees: Genentech, Inc., The Regents of the University of California
    Inventors: Fred de Sauvage, Christian Siebel, Brian Biehs, Hua Tian, Ophir Klein
  • NOTCH PATHWAY INHIBITION
    Publication number: 20160068596
    Abstract: The invention provides Notch pathway inhibition with reduced toxicity.
    Type: Application
    Filed: July 9, 2015
    Publication date: March 10, 2016
    Inventors: Fred de Sauvage, Christian Siebel, Brian Biehs, Hua Tian
  • ANTI-NOTCH1 NRR ANTIBODIES AND METHODS USING SAME
    Publication number: 20090258026
    Abstract: The invention provides anti-Notch1 NRR antibodies, and compositions comprising and methods of using these antibodies.
    Type: Application
    Filed: June 3, 2008
    Publication date: October 15, 2009
    Applicant: Genentech, Inc.
    Inventors: Christian Siebel, Yan Wu
  • Gene targeting vectors comprising conditional positive selection markers
    Patent number: 6929909
    Abstract: The present invention is directed to methods and compositions useful in producing cells and animals having a disruption or modification of a target gene. Vectors useful in producing these cells and animals are described. In addition, methods of screening and enriching cells comprising a targeted gene modification are provided.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: August 16, 2005
    Assignee: Deltagen, Inc.
    Inventors: Christian Siebel, Thomas J. Brennan
  • Methods of producing cells and animals comprising targeted gene modifications and compositions relating thereto
    Publication number: 20030032175
    Abstract: The present invention is directed to methods and compositions useful in producing cells and animals having a disruption or modification of a target gene. Vectors useful in producing these cells and animals are described. In addition, methods of screening and enriching cells comprising a targeted gene modification are provided.
    Type: Application
    Filed: September 17, 2001
    Publication date: February 13, 2003
    Inventors: Christian Siebel, Thomas J. Brennan