Patents by Inventor Christian Sievert

Christian Sievert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified microorganisms for chemical production
    Patent number: 10125178
    Abstract: The present invention relates to increasing xylose utilization in industrial microbe by inducing mutations in the regulator genes, crp and xylR. Thus the invention is directed to isolated nucleic acid sequences that encode mutations in the crp gene and the xylR gene and recombinant bacterium that express mutated CRP and XylR. In some embodiments, the mutation results in a point mutation at residue 142 of the CRP protein and/or at point mutation at residues 121, 182 and/or 363 of the XylR protein (based on the protein sequences in E. coli). The invention also includes methods of using the recombinant bacterium.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: November 13, 2018
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Xuan Wang, Reed Cartwright, Christian Sievert, Taylor Loeffler, Lizbeth Nieves, Larry Panyon, Chandler Morris
  • MODIFIED MICROORGANISMS FOR CHEMICAL PRODUCTION
    Publication number: 20160362456
    Abstract: The present invention relates to increasing xylose utilization in industrial microbe by inducing mutations in the regulator genes, crp and xylR. Thus the invention is directed to isolated nucleic acid sequences that encode mutations in the crp gene and the xylR gene and recombinant bacterium that express mutated CRP and XylR. In some embodiments, the mutation results in a point mutation at residue 142 of the CRP protein and/or at point mutation at residues 121, 182 and/or 363 of the XylR protein (based on the protein sequences in E. coli). The invention also includes methods of using the recombinant bacterium.
    Type: Application
    Filed: June 8, 2016
    Publication date: December 15, 2016
    Inventors: Xuan Wang, Reed Cartwright, Christian Sievert, Taylor Loeffler, Lizbeth Nieves, Larry Panyon, Chandler Morris