Abstract: The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds. More particularly, the present embodiments disclosed herein relate to novel side chains, that when coupled to a taxane, are useful for the synthesis of pharmaceutically useful taxanes. Methods of forming the novel side chains and coupling them to hindered alcohols, namely taxanes resulting in useful esters are also disclosed. Various taxanes compounds are known to exhibit anti-tumor activity.

Abstract: A temperature sensor comprising: a hollow tube with a first end and a second end, wherein the second end is closed sealing a cavity within the tube from an environment outside of the tube and wherein the first end has an exterior cylindrical surface; a temperature responsive sensing element within the tube proximate to the second end; a glass cylinder having an inner cylindrical surface in sealing engagement with the exterior cylindrical surface of the first end of the tube; and a sensor housing having an inner cylindrical cavity bounded by an inner cylindrical wall, wherein an outer cylindrical surface of the glass cylinder is sealingly engaged with the inner cylindrical wall.