Abstract: A steering gear for an electromechanical steering system for a vehicle includes an input shaft that can be coupled or connected to a steering column of the steering system, a segment shaft that can be coupled or connected to a steering column lever of the steering system, an angular gear, a servo gear, and an electric motor for driving the servo gear. The angular gear is designed as a bevel gear. The input shaft and the electric motor are connected to the servo gear. The servo gear is connected to the angular gear. The angular gear is connected to the segment shaft. The angular gear is formed to transmit torque from the servo gear to the segment shaft via two transmission paths.

Abstract: Herein is reported a method for determining the binding interaction with a multimeric antigen of an antibody of the human IgG1 subclass that has at least two binding sites specifically binding to the antigen comprising the steps of 1) determining the binding affinity of the antibody for the multimeric antigen, and 2) incubating a mixture comprising the antibody and a polypeptide that is derived from lysine-gingipain of Porphyromonas gingivalis under conditions and for a time sufficient to cleave the antibody into Fabs and Fc-region, and determining the binding affinity of the Fabs of the antibody for the multimeric, whereby the binding affinity of the antibody to the multimeric antigen to be affinity-driven if the binding affinity determined in both steps are comparable and to be avidity-driven if the binding affinity determined in both steps are different.

Abstract: A thermal and acoustic insulation system for an aircraft, to be received between an inner surface of an aircraft primary structure, such as an aircraft fuselage structure, and a surface of a panel arrangement delimiting an aircraft cabin, the surface facing away from the aircraft cabin, comprises an insulation package and at least one sensor adapted to measure a level of humidity present in the insulation package. The insulation package comprises a core layer having a thermal and acoustic damping performance, and a packing layer enclosing the core layer. The packing layer is provided with a plurality of normally closed and selectively openable drainage openings which are actuatable to change between their normally closed state and an open state.

Abstract: A multifunctional thermal and acoustic insulation system having a multilayer structure and a plurality of functional components formed integrally and non-exchangeably with the multilayer structure. The multilayer structure has a thermal and acoustic damping performance and comprises, in a stacked arrangement, a continuous first outer layer, a core layer and a continuous second outer layer. The core layer is between the outer layers so that the outer layers cover the core layer at least on opposite sides thereof. Functions of the functional components are related to at least one of the thermal and the acoustic damping performance of the multilayer structure and the functional components are provided on a first outer layer side of the core layer and/or on a second outer layer side of the core layer.

Abstract: An apparatus for decoding a sequence of pictures from a data stream is configured for decoding a picture of the sequence by: deriving a residual transform signal of the picture from the data stream; combining the residual transform signal with a buffered transform signal of a previous picture of the sequence so as to obtain a transform signal of the picture, the transform signal representing the picture in spectral components; and subjecting the transform signal to a spectral-to-spatial transformation, wherein the buffered transform signal comprises a selection out of spectral components representing the previous picture.

Abstract: A method of generating customizable goal representation is disclosed. A request from a user to view a goal representation is received. A flexible goal ontology is accessed that comprises one or more goal entities, one or more goal relationships between the goal entities, or one or more goal properties, the one or more goal properties including one or more metadata attributes relating to the one or more goal entities. A set of mapping rules is obtained that defines mappings between one or more goals. The set of mapping rules is evaluated to assemble a customized goal representation tailored to the user. The customized goal representation is updated based on a revaluation of the mapping rules affected by changes to the one or more goal entities, the one or more goal relationships, or the one or more properties.

Abstract: A method of implementing administrative services for a compensation platform is disclosed. One or more interactive compensation representation views are generated based on an evaluation of mapping rules against a flexible ontology and current data state, the flexible ontology comprising customizable compensation components, relationships, and properties. One or more compensation representation views are dynamically updated in real-time in response to changes in compensation data, user context, or access permissions without requiring manual regeneration of the one or more compensation representations. The one or more interactive compensation representation views include a user interface element displayed in response to a user selection of compensation data, wherein the user interface element provides direct access to compensation information relevant to the selected compensation data without requiring a change to another screen or another user context.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: Herein is reported the use of a binding assay of a bivalent, bispecific antibody that has the smaller kD value (dissociation constant) for the interaction with its antigen for the immobilization of the bivalent, bispecific antibody to a solid surface for the determination of the biological activity of the bivalent, bispecific antibody.

Abstract: A luminophore having the general empirical formula X?1?xA?y(Al1+zA?3?z)O4:E? that crystallizes in a tetragonal crystal system. X? may be Mg, Ca, Sr, Ba, and combinations thereof; A? may be Li, Na, K, Rb, Cs, and combinations thereof; E? may be Eu, Ce, Yb, Mn, and combinations thereof; 0<x<0.25; y?x; and z=0.5(2x?y).

Abstract: A machine (1) for preparing a beverage (7) has a mixing unit (10) that includes: a stationary support (11); a seat (12); a closure part (13) configured to close and open the seat (12); a wall part (14) that is movable inside the seat (12). The seat (12), the closure part (13) and the wall part (14) are relatively movable between an ingredient transfer configuration and a mixing chamber configuration. The mixing unit (10) has a maintenance guide (111a,112c) and a gate (111b) configured to open and close the maintenance guide (111a,112c). At least one of the frame (11), the seat (12), the closure part (13) and the wall part (14) is/are configured to enter the maintenance guide (111a,112c) when the gate (111b) is open and to be relatively moved into a maintenance configuration for carrying out a maintenance operation.

Abstract: A semi-active noise control system includes a layer configured to be part of an interior panel of an aircraft The layer includes conductive tracks, a driver arrangement, tuned mass dampers, and sensors. Each tuned mass damper has an eigenfrequency that depends on a control signal applied to the tuned mass damper and is connected to the driver arrangement via a conductive track and configured to receive control signals from the driver arrangement. Each sensor is connected to the driver arrangement via a conductive track and is configured to sense vibrations and/or acoustic sounds and send measurement signals to the driver arrangement. The driver arrangement is configured to analyze the measurement signals and to generate and send control signals to the tuned mass dampers such that the eigenfrequency of the tuned mass dampers is matched with the frequency of the vibrations and/or acoustic sounds sensed by the sensors.

Abstract: A machine (1) for serving a beverage (7) via a dispensing outlet (8) to a consumer receptacle (9) by mixing water (3) from a water source (3?) with a flavouring ingredient (2), has a mixing unit (10) that comprises: a stationary support (11); a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12). The seat (12), the closure part (13) and the wall part (14) are: mounted to the support (11); and relatively movable between a transfer configuration and a mixing chamber configuration in which the seat (12) and the closure part (13) and the wall part (14) form a mixing chamber (12?) fluidically connected with the water source (3?). The seat (12) is configured to move relatively to the support (11) according to simultaneous and/or successive geometric translation and geometric rotation.

Abstract: A machine (1) for serving a beverage (7) via a dispensing outlet (8) to a consumer receptacle (9) by mixing water (3) from a water source (3?) with a flavouring ingredient (2), has a mixing unit (10) that comprises: a stationary support (11); a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12). The seat (12), the closure part (13) and the wall part (14) are: mounted to the support (11); and relatively movable between a transfer configuration and a mixing chamber configuration in which the seat (12) and the closure part (13) and the wall part (14) form a mixing chamber (12?) fluidically connected with the water source (3?). The mixing unit (10) further comprises a waste ingredient remover (20) configured to remove a waste ingredient (2?) from the ingredient opening (120) upon beverage preparation.

Abstract: A machine (1) for serving a beverage (7) via a dispensing outlet (8) to a consumer receptacle (9) by mixing water (3) from a water source (3) with a flavouring ingredient (2), has a mixing unit (10) that comprises: a stationary support (11); a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12).

Abstract: A machine (1) for serving a beverage (7) via a dispensing outlet (8) to a consumer receptacle (9) by mixing water (3) from a water source (3?) with a flavouring ingredient (2), has a mixing unit (10) that comprises: a stationary support (11); a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12) by a wall part actuator (17). The seat (12), the closure part (13) and the wall part (14) are: mounted to the support (11); and relatively movable between a transfer configuration and a mixing chamber configuration in which the seat (12) and the closure part (13) and the wall part (14) form a mixing chamber (12?) fluidically connected with the water source (3?).

Abstract: A machine (1) for serving a beverage (7) via a dispensing outlet (8) to a consumer receptacle (9) by mixing water (3) from a water source (3?) with a flavouring ingredient (2), has a mixing unit (10) that comprises: a stationary support (11); a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12). The seat (12), the closure part (13) and the wall part (14) are: mounted to the support (11); and relatively movable between a transfer configuration and a mixing chamber configuration in which the seat (12) and the closure part (13) and the wall part (14) form a mixing chamber (12?) fluidically connected with the water source (3?). The machine (1) has a control unit (C) that is configured to control a preconditioning of the flavouring ingredient after an introduction into the seat's ingredient opening (120).

Abstract: A machine (1) for handling a flavouring ingredient (2), preparing and serving a beverage (7) via a dispensing outlet (8) comprises: a support (11) that is stationary during the handling of the flavouring ingredient; a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12). The seat (12), the closure part (13) and the wall part (14) are directly or indirectly mounted to the support (11) and relatively movable between a transfer configuration and a mixing chamber configuration. The support (11) and the seat (12) are connected by a guide-rail arrangement (111,112) that is stationary relative to the support (11) and a guide-rail counter-member arrangement (121,122) that is stationary relative to the seat (12), or vice versa. The guide-rail arrangement has a first guide-rail section (111) and a second guide-rail section (112).

Abstract: A machine (1) for serving a beverage (7) via a dispensing outlet (8) to a consumer receptacle (9) by mixing water (3) from a water source (3?) with a flavouring ingredient (2), has a mixing unit (10) that comprises: a stationary support (11); a seat (12) having an ingredient opening (120); a closure part (13) configured to close and open the ingredient opening (120); and a wall part (14) that is movable inside the seat (12). The seat (12), the closure part (13) and the wall part (14) are: mounted to the support (11); and relatively movable between a transfer configuration and a mixing chamber configuration in which the seat (12) and the closure part (13) and the wall part (14) form a mixing chamber (12?) fluidically connected with the water source (3?). The machine (1) has a control unit (C) that is configured to control a preconditioning of the flavouring ingredient after an introduction into the seat’s ingredient opening (120).

Abstract: A thermally tempered glass element is provided made of glass with two opposite faces that are under compressive stress of at least 40 MPa. The glass has a working point at which the glass has a viscosity of 104 dPa·s of at most 1350° C. The glass has a viscosity versus temperature profile and a coefficient of thermal expansion versus temperature profile of the glass are such that a variable (750° C.-T13)/(CTELiq-CTEsSol) has a value of at most 5*106 K2. The CTELiq is a coefficient of linear thermal expansion of the glass above a glass transition temperature Tg, the CTESol is a coefficient of linear thermal expansion of the glass in a temperature range from 20° C. to 300° C., and the T13 is a temperature at which the glass has a viscosity of 1013 dPa·s.