Abstract: A system for producing fluid for peritoneal dialysis (PD) is disclosed. The system includes a fluid path including two or more PD concentrate connectors that are each connected to a source of PD concentrate fluid, and an inlet connector connected to a fluid line arranged for transportation of effluent fluid from a patient. The system also includes a forward osmosis (FO)-unit including a draw side and a feed side separated by a FO-membrane. The FO-unit is fluidly connected to the fluid path and receives one or more PD concentrate fluids at the draw side and the effluent at the feed side. Water is transported from the effluent to the one or more PD concentrate fluids through the FO-membrane via an osmotic pressure gradient between the draw side and the feed side, thereby diluting the one or more PD concentrate fluids into a diluted PD concentrate fluid.

Abstract: A system and method for producing fluid for peritoneal dialysis (PD) is disclosed. The system comprises a fluid path including one or more PD-concentrate connectors each connected to one or more sources of PD-concentrate fluid, and a water connector connected to a source of water. The system further includes a forward osmosis FO-unit including a draw side and a feed side separated by a FO-membrane. The FO-unit is fluidly connected to the fluid path. The FO-unit receives the one or more PD-concentrate fluids at the draw side, and receives the water at the feed side. Purified water is transported to one or more PD-concentrate fluids through the FO-membrane by means of an osmotic pressure gradient between the draw side and the feed side. The transported purified water is further purified by the FO-membrane and the one or more PD-concentrate fluids is diluted to produce a diluted PD-concentrate fluid.

Abstract: A blood ultrafiltration system comprises a blood filter with first and second compartments separated by a semipermeable membrane. Blood input and blood output lines are connected in fluid communication with the first compartment. An effluent line is connected in fluid communication with the second compartment. A peristaltic pump is arranged for repeated engagement with first and second line segments. In a first arrangement, the first line segment is part of the blood input line or the blood output line and the second line segment is part of the effluent line. In a second arrangement, the first line segment is part of the blood input line and the second line segment is part of the blood output line. The system is operable, by the peristaltic pump, to pump blood through the blood filter and control the extraction of ultrafiltrate in the blood filter.

Abstract: A signal filtering device implements a filtering method that involves operating a digital filter (60) on a pressure signal (p), which represents fluid pressure in a medical apparatus, to produce a filtered signal (y). The method further comprises detecting or predicting presence of a disturbance in the pressure signal (p), and selectively modifying a state vector of the digital filter (60) at a selected time point subsequent to the disturbance in the pressure signal (p), so as to suppress influence of the disturbance on the filtered signal (y). The state vector may be modified by replacing the state vector of the digital filter (60) at the selected time point (t2) by a dedicated reconfiguration state vector (Z?).

Abstract: A control unit (30) is arranged to control a dialysis fluid distribution system (12) comprising two volumetric pumps (P1, P2) and a dialyzer (13). The control unit (30) is operable in a calibration mode, to establish a bypass flow path that bypasses the dialyzer (13) and extends between the pumps (P1, P2) and to operate the pumps (P1, P2) at first and second calibration speeds so as to balance the flow rates generated by the pumps (P1, P2), e.g. based on a measured pressure or fluid level in dialysis fluid distribution system (12). The control unit (30) determines, based on the first and second calibration speeds, a relation between the stroke volumes of the pumps (P1, P2).

Abstract: A control unit (30) is arranged to control a dialysis fluid distribution system (12) comprising two volumetric pumps (P1, P2) and a dialyzer (13). The control unit (30) is operable in a calibration mode, to establish a bypass flow path that bypasses the dialyzer (13) and extends between the pumps (P1, P2) and to operate the pumps (P1, P2) at first and second calibration speeds so as to balance the flow rates generated by the pumps (P1, P2), e.g. based on a measured pressure or fluid level in dialysis fluid distribution system (12). The control unit (30) determines, based on the first and second calibration speeds, a relation between the stroke volumes of the pumps (P1, P2).