Abstract: The present invention relates to a microfluidic particle analysis device comprising an inlet and an outlet in fluid communication via a main channel defining a main flow direction from an inlet end to an outlet end, the main channel being defined by a main channel wall extending from the inlet end to the outlet end and having a first cross-sectional dimension in the range of 20 ?m to 120 ?m and a second cross-sectional dimension of at least 100 ?m, the main channel wall at a vertex having an opening extending along the main flow direction and being open to an analysis section having surfaces at an analytical distance in the range of 5 ?m to 50 ?m and a sensor system for detecting a particle. The present invention also relates to a method of using the microfluidic particle analysis device for detecting particles or monitoring the concentration of particles.

Abstract: The present invention relates to a microfluidic particle analysis device comprising an inlet and an outlet in fluid communication via a main channel defining a main flow direction from an inlet end to an outlet end, the main channel being defined by a main channel wall extending from the inlet end to the outlet end and having a first cross-sectional dimension in the range of 20 ?m to 120 ?m and a second cross-sectional dimension of at least 100 ?m, the main channel wall at a vertex having an opening extending along the main flow direction and being open to an analysis section having surfaces at an analytical distance in the range of 5 ?m to 50 ?m and a sensor system for detecting a particle. The present invention also relates to a method of using the microfluidic particle analysis device for detecting particles or monitoring the concentration of particles.

Abstract: The present invention relates to a microfluidic particle analysis device comprising an inlet and an outlet in fluid communication via a main channel defining a main flow direction from an inlet end to an outlet end, the main channel being defined by a main channel wall extending from the inlet end to the outlet end and having a first cross-sectional dimension in the range of 20 ?m to 120 ?m and a second cross-sectional dimension of at least 100 ?m, the main channel wall at a vertex having an opening extending along the main flow direction and being open to an analysis section having surfaces at an analytical distance in the range of 5 ?m to 50 ?m and a sensor system for detecting a particle. The present invention also relates to a method of using the microfluidic particle analysis device for detecting particles or monitoring the concentration of particles.

Abstract: A microfluidic particle analysis device comprising an inlet with an inlet manifold providing parallel fluid communication with a bypass channel and a measuring channel having a sensor system for detecting a particle, wherein the angle of the measuring channel relative to the main flow direction is in the range of 0° to 60°, and wherein the angle of the bypass channel relative to the main flow direction is in the range of 0° to 60°. The present invention also relates to a method of using the device microfluidic particle analysis.

Abstract: The present invention relates to a microfluidic particle analysis device comprising an inlet in fluid communication via a main channel defining a main flow direction with an inlet manifold providing parallel fluid communication with a bypass channel of hydrodynamic resistance Rbypass, and a measuring channel of hydrodynamic resistance Rmeasuring, the measuring channel having a cross-sectional dimension in the range of from 1 ?m to 50 ?m and further having a sensor system for detecting a particle, wherein a flow distribution parameter Xmeasuring=Rmeasuring?1(Rmeasuring?1+Rbypass?1)?1 is in the range from 10?6 to 0.25, wherein the angle of the measuring channel relative to the main flow direction is in the range of 0° to 60°, and wherein the angle of the bypass channel relative to the main flow direction is in the range of 0° to 60°, and the microfluidic particle analysis device further comprising an outlet in fluid communication with the bypass channel and the measuring channel.