Patents by Inventor Christian WEILE

Christian WEILE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240327837
    Abstract: The present invention relates to antisense oligonucleotides which are complementary to conserved TDP-43 binding sites on pre-mRNA transcripts, which are capable of restoring RNA binding protein function in the processing of multiple independent mRNAs in TDP-43 depleted cells.
    Type: Application
    Filed: February 7, 2024
    Publication date: October 3, 2024
    Inventors: Congwei WANG, Christian WEILE, Martin EBELING, Lars JOENSON, Jonas VIKESAA, Ravi JAGASIA, Meiling LI
  • Patent number: 12084657
    Abstract: The present invention relates to antisense oligonucleotides which are complementary to conserved TDP-43 binding sites on pre-mRNA transcripts, which are capable of restoring RNA binding protein function in the processing of multiple independent mRNAs in TDP-43 depleted cells.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: September 10, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Congwei Wang, Christian Weile, Martin Ebeling, Lars Joenson, Jonas Vikesaa, Ravi Jagasia, Meiling Li
  • Publication number: 20240167040
    Abstract: The present invention relates to antisense oligonucleotides that reduce expression of A1CF, as well as conjugates, salts and pharmaceutical compositions thereof. The invention also relates to uses of such antisense oligonucleotides, conjugates, salts and pharmaceutical compositions in methods for reducing A1CF expression and in medical uses and methods of treatment of disease, particularly treatment of hepatitis B virus (HBV) infection.
    Type: Application
    Filed: February 17, 2023
    Publication date: May 23, 2024
    Inventors: Gitte Friis, Helene Maria Gylling, Dennis Jul Hansen, Erich Koller, Anaïs Irène Marie Lopez, Dénia Mellal, Susanne Mohr, Lykke Pedersen, Johanna Marie Pose Vicente, Sabine Sewing, Christian Weile
  • Publication number: 20220033818
    Abstract: The present invention relates to antisense oligonucleotides which are complementary to conserved TDP-43 binding sites on pre-mRNA transcripts, which are capable of restoring RNA binding protein function in the processing of multiple independent mRNAs in TDP-43 depleted cells.
    Type: Application
    Filed: July 23, 2021
    Publication date: February 3, 2022
    Inventors: Congwei WANG, Christian WEILE, Martin EBELING, Lars JOENSON, Jonas VIKESAA, Ravi JAGASIA, Meiling LI