Abstract: Provided herein are trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation, and wherein and a second pair of polypeptides possess a single variable domain forming a single antigen binding site. In some embodiments, the binding proteins comprise a binding site that binds a CD28 polypeptide, a binding site that binds a CD3 polypeptide, and a binding site that binds a third polypeptide, such as a tumor target protein. In some embodiments, the binding proteins comprise four polypeptide chains that form three antigen binding sites that specifically bind one or more HIV target proteins. The disclosure also relates to methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

Abstract: A semiconductor device has a power switching component configured to control the flow of current through a load path, a current sensing component configured to sense the current flow through the load path, and an electrostatic discharge “ESD” protection component configured to protect the current sensing component from an electrostatic discharge. The ESD protection component has an ESD transistor. The ESD transistor has a gate that connected to a discharge path so that the presence of a discharge of a first polarity causes the ESD transistor to switch on to form a further path for dissipation of a discharge.

Abstract: A fluid pump for a motor vehicle, having a housing, an impeller for conveying a fluid through a fluid chamber of the housing, an electric motor with a stator inside a stator space of the housing for driving an electric motor rotor coupled to the impeller, and a containment shell which separates a wet space of the fluid pump from a dry space of the fluid pump. The containment shell joined to the stator is arranged at least elastically compressed between two fastened together housing parts and rests against the stator and a pump stage housing portion, and the containment shell braces the stator against the housing and thereby fixes the stator relative to the housing in the longitudinal direction of the fluid pump.

Abstract: A memory device comprising a plurality of memory cells situated in a first cell field, multiple first bit lines, each respectively connected to multiple memory cells of the first cell field to enable access to the memory cells via the bit line, and multiple sense amplifier pairs which respectively comprise a first and a second sense amplifier. Each first bit line is assigned to a sense amplifier pair, each first bit line being connected to a respective first semiconductor switch element, through which the bit line is electroconductively connectible to and insulatable from the first sense amplifier of the sense amplifier pair, to which the bit line is assigned. Each first bit line is connected to a respective second semiconductor switch element, through which the bit line is electroconductively connectible to and insulatable from the second sense amplifier of the sense amplifier pair, to which the bit line is assigned.

Abstract: A memory device comprising a cell field having memory cells, N bit lines, which are respectively connected to at least one of the memory cells of the cell field, N being a whole number greater than one, N sense amplifiers; a bit shift circuit, which has S switch element rows, S being a whole number greater than one and a row number in the range from zero to S?1 being assignable to each switch element row. Each switch element row includes at least one semiconductor switch element connected to one of the bit lines and one of the sense amplifiers. Switch elements of each row connect all bit lines, whose bit line number is smaller than or equal to N minus the row number, to sense amplifiers, so that the respective sense amplifier number is equal to the respective bit line number plus the row number.

Abstract: A distance measuring device comprising an optical transmitter channel for transmitting laser light along a transmitter path and an optical reception channel for receiving laser light along a reception path. At least one optical element including a glass part with a coated surface is positioned in the optical transmitter channel or in the optical reception channel. The glass part includes a glass pane with a thickness below 0.3 mm, with a peripheral edge and with a coating on at least one of the two surfaces, and a ring element. The glass pane is adhesively connected to an end face of the ring element. This distance measuring device shows reduced measuring artefacts and/or reduced optical aberration effects and/or a reduced weight.

Abstract: A distance measuring device comprising an optical transmitter channel for transmitting laser light along a transmitter path and an optical reception channel for receiving laser light along a reception path. At least one optical element including a glass part with a coated surface is positioned in the optical transmitter channel or in the optical reception channel. The glass part includes a glass pane with a thickness below 0.3 mm, with a peripheral edge and with a coating on at least one of the two surfaces, and a ring element. The glass pane is adhesively connected to an end face of the ring element. This distance measuring device shows reduced measuring artefacts and/or reduced optical aberration effects and/or a reduced weight.

Abstract: A valve includes: a drive; a plunger connected to the drive; and two closing bodies connected to the plunger and movable by the plunger such that the two closing bodies are movable into abutment against respective sealing seats or away from the respective sealing seats. The two closing bodies are arranged fixedly on a sleeve, and the sleeve is slidable onto the plunger and connected fixedly to the plunger.

Abstract: A memory device comprising a plurality of memory cells situated in a first cell field, multiple first bit lines, each respectively connected to multiple memory cells of the first cell field to enable access to the memory cells via the bit line, and multiple sense amplifier pairs which respectively comprise a first and a second sense amplifier. Each first bit line is assigned to a sense amplifier pair, each first bit line being connected to a respective first semiconductor switch element, through which the bit line is electroconductively connectible to and insulatable from the first sense amplifier of the sense amplifier pair, to which the bit line is assigned. Each first bit line is connected to a respective second semiconductor switch element, through which the bit line is electroconductively connectible to and insulatable from the second sense amplifier of the sense amplifier pair, to which the bit line is assigned.

Abstract: A memory device comprising a cell field having memory cells, N bit lines, which are respectively connected to at least one of the memory cells of the cell field, N being a whole number greater than one, N sense amplifiers; a bit shift circuit, which has S switch element rows, S being a whole number greater than one and a row number in the range from zero to S?1 being assignable to each switch element row. Each switch element row includes at least one semiconductor switch element connected to one of the bit lines and one of the sense amplifiers. Switch elements of each row connect all bit lines, whose bit line number is smaller than or equal to N minus the row number, to sense amplifiers, so that the respective sense amplifier number is equal to the respective bit line number plus the row number.

Abstract: A valve includes: a drive; a plunger connected to the drive; and two closing bodies connected to the plunger and movable by the plunger such that the two closing bodies are movable into abutment against respective sealing seats or away from the respective sealing seats. The two closing bodies are arranged fixedly on a sleeve, and the sleeve is slidable onto the plunger and connected fixedly to the plunger.

Abstract: A distance measuring device comprising an optical transmitter channel for transmitting laser light along a transmitter path and an optical reception channel for receiving laser light along a reception path. At least one optical element including a glass part with a coated surface is positioned in the optical transmitter channel or in the optical reception channel. The glass part includes a glass pane with a thickness below 0.3 mm, with a peripheral edge and with a coating on at least one of the two surfaces, and a ring element. The glass pane is adhesively connected to an end face of the ring element. This distance measuring device shows reduced measuring artefacts and/or reduced optical aberration effects and/or a reduced weight.

Abstract: A valve arrangement for a motor vehicle has a valve plunger fixedly connected to a closure member, a valve housing, a valve seat, an electric motor configured to move the valve plunger, and a worm gear has an outer thread and an inner thread. The valve plunger has, at least in a sub-region, an outer thread and the valve arrangement has a threaded sleeve with an inner thread or a spindle nut with an inner thread, or the valve plunger is fixedly connected to a component having an inner thread and the valve arrangement has an outer thread. The valve plunger is connected to a first gearwheel, and the valve arrangement has at least one second gearwheel. The second gearwheel is arranged such that it can transmit a rotational movement directly, or via an intermediate gearing, to the first gearwheel.

Abstract: A valve for opening up or closing off a flow path includes: a valve disk; a valve tappet having: a central axis, a first end region adjacent to the valve disk, and a second end region facing away from the valve disk; and a transmission device configured to transmit a rotational movement into a translational movement. The transmission device includes: a toothed segment, and a rocker lever mounted so as to be rotatable, about a rocker lever axis of rotation, by a drive plate via the toothed segment. The rocker lever is connected to the valve tappet by pushrods, the pushrods being mounted rotatably in relation to the rocker lever and the valve tappet.

Abstract: A valve for opening or closing a flow section has: a valve disk, a valve plunger and a transmission for converting rotary motion into translational motion. The transmission has a rocker arm mounted to rotate about an axis of relation, the rocker arm is linked to the valve plunger by connecting rods, and the connecting rods are mounted to rotate relative to the rocker arm and the valve plunger. A restoring device generates a force component to counteract a movement of the valve plunger transmitted to the valve plunger by the rocker arm and the connecting rods.

Abstract: A valve for opening up or closing off a flow path includes: a valve disk; a valve tappet having: a central axis, a first end region adjacent to the valve disk, and a second end region facing away from the valve disk; and a transmission device configured to transmit a rotational movement into a translational movement. The transmission device includes: a toothed segment, and a rocker lever mounted so as to be rotatable, about a rocker lever axis of rotation, by a drive plate via the toothed segment. The rocker lever is connected to the valve tappet by pushrods, the pushrods being mounted rotatably in relation to the rocker lever and the valve tappet.

Abstract: A linear actuator for driving an actuating member of an internal combustion engine of a motor vehicle, the linear actuator having two rolling bearings for scanning mutually opposing sides of a rib that is formed as a guide curve. The rib has a variable width, against which the two sensing bodies are biased to reduce or eliminate undesired reaction forces.

Abstract: A method and a related DRAM controller for refreshing a DRAM with an external multi-row, multi-bank refresh function based on optimized command sequences involves determining, at initialization time of the DRAM, inter-operation timing parameters for the external multi-row, multi-bank refresh function, determining optimized timing parameters for row-level activation (ACT) and pre-charge (PRE) commands, and applying the optimized timing parameters for the row-level ACT and PRE commands for refreshing the DRAM with the external multi-row multi-bank refresh function. The auto-refresh function of an SDRAM is replaced.

Abstract: A method and a related DRAM controller for refreshing a DRAM with an external multi-row, multi-bank refresh function based on optimized command sequences involves determining, at initialization time of the DRAM, inter-operation timing parameters for the external multi-row, multi-bank refresh function, determining optimized timing parameters for row-level activation (ACT) and pre-charge (PRE) commands, and applying the optimized timing parameters for the row-level ACT and PRE commands for refreshing the DRAM with the external multi-row multi-bank refresh function. The auto-refresh function of an SDRAM is replaced.

Abstract: A valve for opening or closing a flow section has: a valve disk, a valve plunger and a transmission for converting rotary motion into translational motion. The transmission has a rocker arm mounted to rotate about an axis of relation, the rocker arm is linked to the valve plunger by connecting rods, and the connecting rods are mounted to rotate relative to the rocker arm and the valve plunger. A restoring device generates a force component to counteract a movement of the valve plunger transmitted to the valve plunger by the rocker arm and the connecting rods.