Patents by Inventor Christian Wenzel Tornoe

Christian Wenzel Tornoe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • New positive allosteric modulators of nicotinic acetylcholine receptor
    Publication number: 20130005743
    Abstract: The present invention relates to compounds useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said compounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine ?7 receptor.
    Type: Application
    Filed: June 29, 2012
    Publication date: January 3, 2013
    Applicant: H. Lundbeck A/S
    Inventors: Jørgen Eskildsen, Christian Wenzel Tornøe
  • Substituted thiomorpholine derivatives
    Patent number: 8299075
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: October 30, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, William Patrick Watson, Andreas Ritzen
  • Substituted pyridine derivatives
    Patent number: 8299071
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Grant
    Filed: September 14, 2010
    Date of Patent: October 30, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Nikolay Khanzhin, Mario Rottlander, William Patrick Watson, Daniel Rodriguez Greve
  • SUBSTITUTED THIOMORPHOLINE DERIVATIVES
    Publication number: 20110294787
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: July 28, 2011
    Publication date: December 1, 2011
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • Substituted thiomorpholine derivatives
    Patent number: 8012962
    Abstract: The present invention relates to thiomorpholine derivatives of formula I or pharmaceutically acceptable salts thereof and their use in treating seizure disorders, anxiety disorders, bipolar disorders, neuropathic pain disorders and migraine pain disorders.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: September 6, 2011
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • SUBSITUTED PYRIDINE DERIVATIVES
    Publication number: 20110003811
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Application
    Filed: September 14, 2010
    Publication date: January 6, 2011
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornøe, Nikolay Khanzhin, Mario Rottländer, William Patrick Watson, Daniel Rodriguez Greve
  • Methods of using substituted morpholine derivatives
    Patent number: 7812023
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: November 5, 2009
    Date of Patent: October 12, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • Substituted pyridine derivatives
    Patent number: 7812020
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: October 12, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Nikolay Khanzhin, Mario Rottländer, William Patrick Watson, Daniel Rodriguez Greve
  • Methods of using substituted morpholine derivatives
    Publication number: 20100063033
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 5, 2009
    Publication date: March 11, 2010
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • SUBSTITUTED ANILINE DERIVATIVES
    Publication number: 20100063044
    Abstract: The present invention relates to aniline derivatives of formula I: wherein R1, R2, R3, R4, Z and q are as defined herein; or salts thereof and their use.
    Type: Application
    Filed: August 17, 2009
    Publication date: March 11, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlãnder, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Publication number: 20100063036
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: November 3, 2009
    Publication date: March 11, 2010
    Applicant: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Patent number: 7632835
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: December 15, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • Substituted aniline derivatives
    Patent number: 7601870
    Abstract: The present invention relates to aniline derivatives of the general formula I or salts thereof, described therein, and their use.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: October 13, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzén, William Patrick Watson
  • METHODS OF USING SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
    Publication number: 20090143369
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: January 28, 2009
    Publication date: June 4, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES
    Publication number: 20090137571
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Application
    Filed: January 28, 2009
    Publication date: May 28, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Mario Rottlander, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • USE OF KCNQ-OPENERS FOR TREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA
    Publication number: 20090118285
    Abstract: The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Furthermore the invention relates to the use of selective KCNQ potassium channel openers for the preparation of a pharmaceutical composition for treating or reducing the symptoms of schizophrenia and related symptoms, disorders and diseases. Furthermore the invention relates to a method of screening for a compound, which is a selective KCNQ potassium channel opener and which is capable of having an anti-psychotic potential.
    Type: Application
    Filed: February 2, 2007
    Publication date: May 7, 2009
    Applicant: H. Lundbeck A/S
    Inventors: Henriette Husum Bak-Jensen, Christian Wenzel Tornoe, Mario Rottlander, Daniel Rodriguez Greve, Nikolay Khanzhin, Andreas Ritzen, William Patrick Watson
  • Substituted morpholine and thiomorpholine derivatives
    Patent number: 7501414
    Abstract: The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: March 10, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Christian Wenzel Tornøe, Mario Rottländer, Nikolay Khanzhin, Andreas Ritzèn, William Patrick Watson
  • Substituted Pyridine Derivatives
    Publication number: 20080318953
    Abstract: The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders.
    Type: Application
    Filed: March 2, 2006
    Publication date: December 25, 2008
    Applicant: H. LUNDBECK A/S
    Inventors: Christian Wenzel Tornoe, Nikolay Khanzhin, Mario Rottlander, William Patrick Watson, Daniel Rodriguez Greve
  • 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system
    Patent number: 7368472
    Abstract: The present invention concerns 1,2,4-triaminobenzene derivatives of the general formula I or pharmaceutically acceptable salts thereof and the use thereof.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: May 6, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Mario Rottlander, Andreas Ritzen, Morten Bang Norgaard, Nikolay Khanzhin, Christian Wenzel Tornoe