Patents by Inventor Christian Wilke

Christian Wilke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11519863
    Abstract: The invention relates to a method in the preparation of samples for microscopic examination onto which a coverslip is applied. The method is notable for the fact that the coverslipping quality is checked automatically and at least partly optically. The invention further relates to an apparatus for carrying out the method, and to an apparatus for checking the coverslipping quality of samples onto which a coverslip is applied.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: December 6, 2022
    Assignee: LEICA BIOSYSTEMS NUSSLOCH GMBH
    Inventors: Bernhard Neef, Christian Wilke, Karl-Heinrich Westerhoff
  • Publication number: 20220056414
    Abstract: The invention relates to a method for producing a material for preparing a substrate for cultivating living cells. The invention further relates to a platelet lysate material and its use.The solution of the problem underlying the invention is based on the combination of at least two different treatments with different virus inactivation procedures.Combining two or more procedures for inactivation of virus particles and/or virus components ensures that a wide range of viruses (e.g. enveloped and non-enveloped viruses) are inactivated so as to provide a safe product for clinical and pharmaceutical applications. Moreover, a platelet lysate material comprising blood platelet lysate is provided, wherein the material is a liquid or dry material that is essentially devoid of vims particles and/or virus components.
    Type: Application
    Filed: August 23, 2019
    Publication date: February 24, 2022
    Applicant: PL BIOSCIENCE GMBH
    Inventors: Hatim HEMEDA, Christian WILKES
  • Publication number: 20200325442
    Abstract: The invention relates to a method for producing a material for preparing a three-dimensional, gel-like substrate, wherein a thrombocyte concentrate is provided and blood platelets are harvested from this thrombocyte concentrate. The blood platelets are then lysed so as to produce a platelet lysate, and said platelet lysate is subsequently lyophilized so as to provide a dry platelet lysate gel material. The invention further concerns a platelet lysate gel material comprising blood platelet lysate, wherein this material is a lyophilized dry material. The lyophilized gel can be easily reconstituted by the addition of water at the place of use in order to provide a completely functional platelet lysate-gel which can be used for cultivating living cells without any limitations. Accordingly, this method facilitates transportation of the gel material and ensures a higher shelf life of the platelet lysate gel without any impact on cell culture properties.
    Type: Application
    Filed: June 1, 2016
    Publication date: October 15, 2020
    Applicants: PL BIOSCIENCE GMBH, PL BIOSCIENCE GMBH
    Inventors: Hatim HEMEDA, Christian WILKES
  • Patent number: 10046780
    Abstract: A method for operating a rail vehicle includes, at least to some extent, using a secondary ETCS device which travels along with the rail vehicle but is not used for its operation, if a fault occurs in a primary ETCS device. A secondary EVC takes over the role of a primary EVC and, in many applications, at least some train control functions. The advantage is that train control can, at least in some fault cases, be continued in an automated way in the case of a failure of a component of the primary ETCS device. A rail vehicle and an apparatus for the operation of a rail vehicle are also provided.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: August 14, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventors: Markus Dymek, Carsten Hasselkuss, Udo Rabeneck, Christian Wilke
  • Publication number: 20180100787
    Abstract: The invention relates to a method in the preparation of samples for microscopic examination onto which a coverslip is applied. The method is notable for the fact that the coverslipping quality is checked automatically and at least partly optically. The invention further relates to an apparatus for carrying out the method, and to an apparatus for checking the coverslipping quality of samples onto which a coverslip is applied.
    Type: Application
    Filed: December 13, 2017
    Publication date: April 12, 2018
    Inventors: Bernhard Neef, Christian Wilke, Karl-Heinrich Westerhoff
  • Patent number: 9880079
    Abstract: The invention relates to a method in the preparation of samples for microscopic examination onto which a coverslip is applied. The method is notable for the fact that the coverslipping quality is checked automatically and at least partly optically. The invention further relates to an apparatus for carrying out the method, and to an apparatus for checking the coverslipping quality of samples onto which a coverslip is applied.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: January 30, 2018
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Bernhard Neef, Christian Wilke, Karl-Heinrich Westerhoff
  • Patent number: 9776647
    Abstract: A method for inputting ETCS data into a rail vehicle inputs the ETCS data by using an apparatus which is separate from the rail vehicle. The apparatus can, for example, be constructed to be mobile and the ETCS data can be input flexibly at different locations and be transmitted to the rail vehicle, for example, by SMS. The advantage of this approach is that delays resulting from the inputting of ETCS data can be reduced and thus the rail vehicle reaches a “Start of Mission” state more quickly. An apparatus for inputting ETCS data into a rail vehicle and a rail vehicle with an ETCS device are also provided.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: October 3, 2017
    Assignee: Siemens Aktiengesellschaft
    Inventors: Markus Dymek, Carsten Hasselkuss, Udo Rabeneck, Christian Wilke
  • Patent number: 9733163
    Abstract: The present invention relates to a holding apparatus (10) for receiving specimen slides (1), having a holder (3, 4, 5) for handling the holding apparatus (10) and having at least two identification units (2a, 2b) that make available different information items to enable characterization of the orientation of the holding apparatus (10) in a stainer or coverslipper.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: August 15, 2017
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Markus Berberich, Christian Wilke, Jurgen Tenhaef
  • Publication number: 20160187236
    Abstract: The present invention relates to a holding apparatus (10) for receiving specimen slides (1), having a holder (3, 4, 5) for handling the holding apparatus (10) and having at least two identification units (2a, 2b) that make available different information items to enable characterization of the orientation of the holding apparatus (10) in a stainer or coverslipper.
    Type: Application
    Filed: March 10, 2016
    Publication date: June 30, 2016
    Inventors: Markus BERBERICH, Christian WILKE, Jurgen TENHAEF
  • Patent number: 9322754
    Abstract: The present invention relates to a holding apparatus (10) for receiving specimen slides (1), having a holder (3, 4, 5) for handling the holding apparatus (10) and having at least two identification units (2a, 2b) that make available different information items to enable characterization of the orientation of the holding apparatus (10) in a stainer or coverslipper.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: April 26, 2016
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Markus Berberich, Christian Wilke, Jürgen Tenhaef
  • Patent number: 9157782
    Abstract: The present invention relates to a coverslipping machine (1) including: a hollow needle (2) for applying mounting medium onto a specimen slide (5); a transparent container (103) to be filled with a liquid; a light source (101) for radiating measurement light in a principal radiating direction (A) into the container (103); and a light sensor (102, 102?) for detecting the measurement light, the light source (101) being arranged with respect to the container (103) in such a way that the radiated measurement light is refracted by a liquid in the container whose fill level exceeds a fill level limit, the light sensor (102, 102?) being arranged with respect to the container (103) in such a way that only measurement light refracted by the liquid or only measurement light not refracted by the liquid is detected.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: October 13, 2015
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Markus Berberich, Christian Wilke, Tobias Trump
  • Publication number: 20150239481
    Abstract: A method for operating a rail vehicle includes, at least to some extent, using a secondary ETCS device which travels along with the rail vehicle but is not used for its operation, if a fault occurs in a primary ETCS device. A secondary EVC takes over the role of a primary EVC and, in many applications, at least some train control functions. The advantage is that train control can, at least in some fault cases, be continued in an automated way in the case of a failure of a component of the primary ETCS device. A rail vehicle and an apparatus for the operation of a rail vehicle are also provided.
    Type: Application
    Filed: September 5, 2013
    Publication date: August 27, 2015
    Inventors: Markus Dymek, Carsten Hasselkuss, Udo Rabeneck, Christian Wilke
  • Publication number: 20150232109
    Abstract: A method for inputting ETCS data into a rail vehicle inputs the ETCS data by using an apparatus which is separate from the rail vehicle. The apparatus can, for example, be constructed to be mobile and the ETCS data can be input flexibly at different locations and be transmitted to the rail vehicle, for example, by SMS. The advantage of this approach is that delays resulting from the inputting of ETCS data can be reduced and thus the rail vehicle reaches a “Start of Mission” state more quickly. An apparatus for inputting ETCS data into a rail vehicle and a rail vehicle with an ETCS device are also provided.
    Type: Application
    Filed: September 5, 2013
    Publication date: August 20, 2015
    Inventors: Markus Dymek, Carsten Hasselkuss, Udo Rabeneck, Christian Wilke
  • Patent number: 8894644
    Abstract: A method and device for treatment of living cells with cold atmospheric pressure plasma while simultaneously applying selective electroporation of the cells are provided. The method is useful for the local selective killing of cancer cells, improvement of wound treatment and sterilization or decontamination of objects.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: November 25, 2014
    Assignee: INP Greifswald Leibniz-Inst fuer Plasmaforschung
    Inventors: Manfred Stieber, Klaus-Dieter Weltmann, Thomas Von Woedtke, Christian Wilke, Uwe Ehrenberg
  • Patent number: 8662818
    Abstract: The invention relates to apparatuses for turning racks (1) for specimen slides (4), having a rack receptacle for at least one rack, the rack (1) being oriented in the rack receptacle horizontally in a first position such that specimen slides in the rack are arranged vertically next to one another relative to a longitudinal axis of the rack, and the rack receptacle being pivotable around a rotation axis (8) into a second position in which the rack (1) is oriented vertically. The rotation axis (8) of the rack (1) extends obliquely with respect to the longitudinal axis (5) of the horizontally oriented rack (1), so that the rack (1) can be pivoted back and forth between the first and the second position by means of a 180-degree rotation around the rotation axis (8).
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: March 4, 2014
    Assignee: LEICA Biosystems Nussloch GmbH
    Inventor: Christian Wilke
  • Patent number: 8540947
    Abstract: During operation of a staining device (20) including a first container (22) filled with a first process medium (23) and a second container (24) filled with a second process medium (25), samples (26) to be stained are immersed in the first process medium (23). A speed representative of how fast the samples (26) are to be withdrawn from the first process medium (23) is determined according to the first process medium (23) and/or according to the samples (26). Subsequently, the samples (26) are withdrawn from the first process medium (23) at the determined speed.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: September 24, 2013
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Markus Berberich, Christian Wilke
  • Publication number: 20130233071
    Abstract: The present invention relates to a coverslipping machine (1) including: a hollow needle (2) for applying mounting medium onto a specimen slide (5); a transparent container (103) to be filled with a liquid; a light source (101) for radiating measurement light in a principal radiating direction (A) into the container (103); and a light sensor (102, 102?) for detecting the measurement light, the light source (101) being arranged with respect to the container (103) in such a way that the radiated measurement light is refracted by a liquid in the container whose fill level exceeds a fill level limit, the light sensor (102, 102?) being arranged with respect to the container (103) in such a way that only measurement light refracted by the liquid or only measurement light not refracted by the liquid is detected.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 12, 2013
    Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBH
    Inventors: Markus Berberich, Christian Wilke, Tobias Trump
  • Patent number: 8524172
    Abstract: A sensor device (45) for calibrating a staining device (20) has a coupling unit (46) which is configured to be attachable to a transport device (22) of the staining device (20). A sensor unit (48) of the sensor device (45) is adapted to detect the presence of components of the staining device (20).
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: September 3, 2013
    Assignee: Leica Biosystems Nussloch GmbH
    Inventors: Markus Berberich, Christian Wilke
  • Patent number: 8205906
    Abstract: The invention relates to a rehabilitation children's sport stroller, comprising a frame (28), a seat (10), and a pivot device (16), which at least in some regions connects the seat (10) to the frame (28) pivotally about a seat pivot axis (S) and comprises a first joint (20) and a second joint (22), which are provided on the seat (10) on mutually opposing sides, wherein the first joint (20) and the second joint (22) can be locked, the first joint (20) comprising a first-joint operating element (40) for releasing the first joint (20). According to the invention, the second joint (22) is connected to the first-joint operating element (40) by means of a push-stable transfer device such that during an actuation of the first-joint operating element (40) the first joint (20) and the second joint (22) are released.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: June 26, 2012
    Assignee: Otto Bock Healthcare GmbH
    Inventors: Oliver Kretschmer, Christian Wilke, Jürgen Christmann
  • Publication number: 20120148380
    Abstract: The invention relates to apparatuses for turning racks (1) for specimen slides (4), having a rack receptacle for at least one rack, the rack (1) being oriented in the rack receptacle horizontally in a first position such that specimen slides in the rack are arranged vertically next to one another relative to a longitudinal axis of the rack, and the rack receptacle being pivotable around a rotation axis (8) into a second position in which the rack (1) is oriented vertically. The rotation axis (8) of the rack (1) extends obliquely with respect to the longitudinal axis (5) of the horizontally oriented rack (1), so that the rack (1) can be pivoted back and forth between the first and the second position by means of a 180-degree rotation around the rotation axis (8).
    Type: Application
    Filed: December 12, 2011
    Publication date: June 14, 2012
    Applicant: LEICA BIOSYSTEMS NUSSLOCH GMBH
    Inventor: Christian WILKE