Patents by Inventor Christiane Rayssiguier

Christiane Rayssiguier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the in vivo recombination of DNA sequences having mismatched bases
    Patent number: 5965415
    Abstract: The present invention relates to a process of recombination in vivo of partially homologous DNA sequences having up to 30% of base mismatches. According to its essential characteristic, said sequences are placed together in cells or an organism of which the enzymatic mismatch repair system is defective or has been transitorily inactivated by saturation for the time to obtain recombination between said DNA sequences or in using mutants which increase the intergeneric recombination.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 12, 1999
    Assignee: Mixis France, S.A.
    Inventors: Miroslav Radman, Christiane Rayssiguier
  • Process for the in vivo recombination of DNA sequences having mismatched bases
    Patent number: 5912119
    Abstract: The present invention relates to a process of recombination in vivo of partially homologous DNA sequences having up to 30% of base mismatches. According to its essential characteristic, said sequences are placed together in cells or an organism of which the enzymatic mismatch repair system is defective or has been transitorily inactivated by saturation for the time to obtain recombination between said DNA sequences or in using mutants which increase the intergeneric recombination.
    Type: Grant
    Filed: April 25, 1994
    Date of Patent: June 15, 1999
    Assignee: Mixis France, S.A.
    Inventors: Miroslav Radman, Christiane Rayssiguier