Patents by Inventor Christiane SEGARRA

Christiane SEGARRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanobeads covered with plasminogen as a direct support for cyclic amplification of the prion protein PrP
    Patent number: 8859298
    Abstract: The present invention relates to an in vitro method for detecting a pathogenic conformational isomer of the prion protein in a sample, said method comprising a preliminary step for capturing the pathogenic conformational isomer by putting the sample into contact with nanobeads covered with a ligand of the pathogenic conformational isomer, and then applying a cyclic amplification of the misfolded prion protein directly on the solid support having captured the pathogenic conformational isomer, and detecting the presence of the pathogenic conformational isomer. The invention also relates to a kit for applying this method and to a method for decontaminating a biological sample.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: October 14, 2014
    Assignee: Etablissement Francais du Sang
    Inventors: Christiane Segarra, Joliette Coste Van Der Luur, Daisy Bougard
  • Nanobeads covered with plasminogen as a direct support for cyclic amplification of the prion protein PrPSC
    Publication number: 20120244559
    Abstract: The present invention relates to an in vitro method for detecting a pathogenic conformational isomer of the prion protein in a sample, said method comprising a preliminary step for capturing the pathogenic conformational isomer by putting the sample into contact with nanobeads covered with a ligand of the pathogenic conformational isomer, and then applying a cyclic amplification of the misfolded prion protein directly on the solid support having captured the pathogenic conformational isomer, and detecting the presence of the pathogenic conformational isomer. The invention also relates to a kit for applying this method and to a method for decontaminating a biological sample.
    Type: Application
    Filed: March 21, 2012
    Publication date: September 27, 2012
    Applicant: Etalissement Français du Sang
    Inventors: Christiane SEGARRA, Joliette COSTE VAN DER LUUR, Daisy BOUGARD