Abstract: Chemical compounds that are useful as inhibitors of mechanotransduction in the treatment of pain and modulation of touch perception and topical administration of the compounds described herein in the treatment of pain and modulation of touch perception.

Abstract: A method may be provided for inactivating biologically active components in a liquid using low-energy electrons generated by an electron source, the electrons having an acceleration voltage of 25 keV to 300 keV. The method comprises the following steps: a) filling a vessel with a liquid volume; b) applying low-energy electrons to a first partial volume of the liquid filled into the vessel, wherein the first partial volume is a maximum of 10% of the liquid volume in the vessel; c) mixing the first partial volume of the liquid, applied with the low-energy electrons, to the second partial liquid volume in the vessel, which has not been applied with low-energy electrons; d) repeating steps b) and c) several times.

Abstract: A method may be provided for stimulating the growth of a biomass, which is mixed with a liquid inside a bioreactor, by means of ionising radiation. The following method steps are used: a) exposing a first partial volume of the liquid in the bioreactor to ionising radiation, the first partial volume comprising at most 10% of the liquid volume in the bioreactor; b) mixing the first partial liquid volume, which has been exposed to ionising radiation, with the second partial liquid volume, which has not been exposed to ionising radiation, in the bioreactor; c) repeating method steps a) and b) multiple times, each partial volume of the liquid in the bioreactor being exposed to a total radiation dose of at most 50 Gy on statistical average.

Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.

Abstract: A method for preparing a transplant obtained from animal or human tissue is provided. The transplant is first deposited in a first liquid that comprises at least one substance that initiates and/or activates collagen cross-linking. After removing the transplant from the first liquid, the transplant, now moistened with said first liquid, is exposed to ultraviolet radiation and then to accelerated low-energy electrons.

Abstract: Chemical compounds that are useful as inhibitors of mechanotransduction in the treatment of pain and modulation of touch perception and topical administration of the compounds described herein in the treatment of pain and modulation of touch perception.

Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.

Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.

Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.

Abstract: The method comprises the following steps: bonding at least one chemical, optically luminescent compound (3) onto at least one indicator element (6) for testing the treatments (14), wherein at least one luminescence property of the chemical compound (3) can be changed; assigning at least one indicator element (6) to the object (1); wherein the indicator element (6) and the object (1) are simultaneously subjected to the same conditions of the energy-introducing treatment (14); changing the luminescence property of the chemical compound (3), wherein the level of the change to the luminescence property depends upon the energy-introducing treatment (14); irradiating (13) the chemical compound (3) with electromagnetic radiation directed onto the indicator (6) for excitation of the luminescence during the energy-introducing treatment or following the energy-introducing treatment (14).

Abstract: Method and device for inactivating a microbiologically contaminated mass containing solid particles. The method includes mixing the mass containing solid particles with a gelatinizing agent, transporting the mixed mass of solid particles and gelatinizing agent through a shaping device structured so that the mixed mass, at least in one area, is shaped to form a lamellar volume with a layer thickness of between 1 mm and 3 mm, and impinging the formed lamellar volume of the mixed mass with accelerated electrons.

Abstract: Method and device for inactivating a microbiologically contaminated mass containing solid particles. The method includes mixing the mass containing solid particles with a gelatinizing agent, transporting the mixed mass of solid particles and gelatinizing agent through a shaping device structured so that the mixed mass, at least in one area, is shaped to form a lamellar volume with a layer thickness of between 1 mm and 3 mm, and impinging the formed lamellar volume of the mixed mass with accelerated electrons.