Patents by Inventor Christianus Johannes Van Koppen

Christianus Johannes Van Koppen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TSH receptor antagonizing tetrahydroquinoline compounds
    Patent number: 9174940
    Abstract: The present invention relates the use of a compound, a pharmaceutical composition, compounds and a kit for treating or preventing disorders in a mammal responsive to TSH receptor mediated pathways, including disorders such as hyperthyroidism, Graves' disease, Graves Ophthalmopathy, Graves' associated pretibial dermopathy, nodular goitre and thyroid cancer comprising administering to said mammal an effective amount of a tetrahydroquinoline compound of Formula (I) or an pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: November 3, 2015
    Assignee: Merck Sharp & Dohme B.V.
    Inventors: Willem Frederik Johan Karstens, Paolo Giovanni Martino Conti, Cornelis Marius Timmers, Ralf Plate, Christianus Johannes Van Koppen
  • TSH receptor antagonizing tetrahydroquinoline compounds
    Publication number: 20110172267
    Abstract: The present invention relates the use of a compound, a pharmaceutical composition, compounds and a kit for treating or preventing disorders in a mammal responsive to TSH receptor mediated pathways, including disorders such as hyperthyroidism, Graves' disease, Graves Ophthalmopathy, Graves' associated pretibial dermopathy, nodular goitre and thyroid cancer comprising administering to said mammal an effective amount of a tetrahydroquinoline compound of Formula (I) or an pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: August 28, 2004
    Publication date: July 14, 2011
    Inventors: Willem Frederik Johan Karstens, Paolo Giovanni Martino Conti, Cornelis Marius Timmers, Ralf Plate, Christianus Johannes Van Koppen