Abstract: A digital dispense apparatus includes at least one fluid dispense device, at least one reservoir fluidically connected to the at least one fluid dispense device, a monolithic carrier structure carrying the at least one fluid dispense device and reservoir, the monolithic carrier forming fluid routing between the reservoir and the fluid dispense device.

Abstract: Systems, methods, and computer readable medium to provide patterned layer deposition of liquid types to a plate surface in layers organized in layouts with sites of patterns aligned to a plate origin of the plate surface. At least one layer includes a layout defining a geometric layout of the plate surface.

Abstract: A slot extender includes a reservoir. The reservoir includes a reservoir floor defining a drain opening, a continuous reservoir sidewall extending from the reservoir floor, and a concave fillet running along at least a portion where the reservoir sidewall joins the reservoir floor. The concave fillet has a variable radius.

Abstract: A slot extender includes a reservoir. The reservoir includes a reservoir floor defining a drain opening, a continuous reservoir sidewall extending from the reservoir floor, and a concave fillet running along at least a portion where the reservoir sidewall joins the reservoir floor. The concave fillet has a variable radius.

Abstract: A slot extender includes a reservoir. The reservoir includes a reservoir floor defining a drain opening, a continuous reservoir sidewall extending from the reservoir floor, and a concave fillet running along at least a portion where the reservoir sidewall joins the reservoir floor. The concave fillet has a variable radius.

Abstract: Various techniques for dispensing liquids are disclosed herein. In one embodiment a dispenser retention apparatus includes a frame. The frame includes a top surface configured to retain a liquid dispensing assembly. The frame also includes a bottom surface opposite the top surface. The bottom surface includes a first channel extending from a first lateral edge of the frame to a droplet passage between the top and bottom surfaces. The first channel is configured to allow a light beam introduced to the frame at the first lateral edge to intersect a droplet in the passage.

Abstract: A slot extender includes a reservoir. The reservoir includes a reservoir floor defining a drain opening, a continuous reservoir sidewall extending from the reservoir floor, and a concave fillet running along at least a portion where the reservoir sidewall joins the reservoir floor. The concave fillet has a variable radius.

Abstract: A liquid dispensing device (10) having a drop ejection device (12) including an orifice (18) adapted for ejecting drops (20) therefrom above a particular turn-on-energy, a turn-on-energy detection device (28) positioned to receive turn-on-energy information from said ejected drops as a function of energy applied to the drop ejection device, and a controller (40) that receives the turn-on-energy information and conducts a mathematical operation on the turn-on-energy information to determine a drop volume of the drops ejected.

Abstract: Various techniques for dispensing liquids are disclosed herein. In one embodiment a dispenser retention apparatus includes a frame. The frame includes a top surface configured to retain a liquid dispensing assembly. The frame also includes a bottom surface opposite the top surface. The bottom surface includes a first channel extending from a first lateral edge of the frame to a droplet passage between the top and bottom surfaces. The first channel is configured to allow a light beam introduced to the frame at the first lateral edge to intersect a droplet in the passage.

Abstract: A liquid dispensing device (10) having a drop ejection device (12) including an orifice (18) adapted for ejecting drops (20) therefrom above a particular turn-on-energy, a turn-on-energy detection device (28) positioned to receive turn-on-energy information from said ejected drops as a function of energy applied to the drop ejection device, and a controller (40) that receives the turn-on-energy information and conducts a mathematical operation on the turn-on-energy information to determine a drop volume of the drops ejected.

Abstract: A microfluidic analysis system for optically analyzing a substance includes a light source having a plurality of selectable single-wavelength light sources, a substance presentation member optically coupled to the light source, and an optical detection system associated with the substance presentation member.

Abstract: Various apparatus and methods relating to determining a quantity measurement of fluid ejected by drop-on-demand nozzles and modifying the ejection parameters based upon the quantity measurement.

Abstract: A method of reducing thickness non-uniformity in a microjet-deposited solids layer is disclosed which comprises depositing onto a substrate by microjet deposition a composition containing a liquid vehicle, at least one reagent; and a polyol which is present at a concentration that enhances thickness uniformity of a solids layer, containing the reagent(s), which is formed when the microjet-deposited composition is dried.

Abstract: A drop-on-demand system for manufacturing diagnostic test strips includes a drop-on-demand mechanism, and a drop volume feedback subsystem and/or a vision subsystem. The drop-on-demand mechanism dispenses one or more reagents on the diagnostic test strips in one or more desired volumes and at one or more desired locations. The drop volume feedback subsystem control volumes of the reagents dispensed by the drop-on-demand mechanism so that the drop-on-demand mechanism dispenses the reagents on the diagnostic test strips in the desired volumes. The vision subsystem aligns the drop-on-demand mechanism in relation to the diagnostic test strips so that the drop-on-demand mechanism dispenses the reagents on the diagnostic test strips at the desired locations.

Abstract: Various apparatus and methods relating to determining a quantity measurement of fluid ejected by drop-on-demand nozzles and modifying the ejection parameters based upon the quantity measurement.

Abstract: A microfluidic analysis system for optically analyzing a substance includes a light source having a plurality of selectable single-wavelength light sources, a substance presentation member optically coupled to the light source, and an optical detection system associated with the substance presentation member.

Abstract: A dispenser for building a lateral flow immunoassay device comprises a fluid supply assembly and a jetting assembly. The fluid supply assembly comprises an antibody component including a plurality of reservoirs to supply at least one of member of a group comprising a species array of at least one species-specific antibody material, an anti-species array of at least one first anti-species antibody material, and a label-antibody array of at least one of a tag material and a second anti-species antibody material. The jetting assembly is in communication with the fluid supply assembly to enable dispensing the materials of the species array, the anti-species array, and the label-antibody array from the supply assembly onto a substrate.

Abstract: A lateral flow device, and related systems and methods is disclosed. A method of building a lateral flow immunoassay device comprises dispensing, via a fluid ejection device, a flow-inducing substance to form a flow membrane, and dispensing, via the fluid ejection device, a measured volume of biosubstances from an array of biosubstances to form a sample module, a tagging module, a reaction module, and a waste module on the membrane.