Patents by Inventor Christie M. Del Castillo

Christie M. Del Castillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric protein for prevention and treatment of HIV infection
    Patent number: 8420099
    Abstract: This invention relates to bispecific fusion proteins effective in viral neutralization. More specifically, such proteins have two different binding domains, an inducing-binding domain and an induced-binding domain, functionally linked by a peptide linker. Such proteins, nucleic acid molecules encoding them, and their production and use in preventing or treating viral infections are provided. One prototypical bispecific fusion protein is sCD4-SCFv(17b), in which a soluble CD4 fragment (containing domains D1 and D2) is fused to a single chain Fv portion of antibody 17b via a linker.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: April 16, 2013
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Edward A. Berger, Christie M. Del Castillo
  • Chimeric protein for prevention and treatment of HIV infection
    Patent number: 7115262
    Abstract: This invention relates to bispecific fusion proteins effective in viral neutralization. More specifically, such proteins have two different binding domains, an inducing-binding domain and an induced-binding domain, functionally linked by a peptide linker. Such proteins, nucleic acid molecules encoding them, and their production and use in preventing or treating viral infections are provided. One prototypical bispecific fusion protein is sCD4-SCFv(17b), in which a soluble CD4 fragment (containing domains D1 and D2) is fused to a single chain Fv portion of antibody 17b via a linker.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: October 3, 2006
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Edward A. Berger, Christie M. Del Castillo