Abstract: An optical filter system and a video endoscope therefor are disclosed. The optical filter system is arranged in a distal end section of a shaft. At least one image sensor for receiving image light is positioned in the distal end section. The optical filter system contains an optical filter and an objective lens system with a three or more lenses to collect image light and to pass it to the image sensor. The filter has transmission characteristics that vary relative to the radial distance from its center and is located between the first lens and the second lens of the objective lens system. Used in conjunction with fluorescence imaging, emission radiation collected by the image sensor is substantially free of excitation radiation. Additionally, a display system clearly delineating the regions with reliable fluorescence and/or visible light is also disclosed.

Abstract: An image capture apparatus for capturing an image of an object of medical interest in reemitted and/or reflected illumination light, for capturing an image of the object in fluorescence light generated by protoporphyrin, and for capturing an image in fluorescence light generated by indocyanine green. The apparatus includes an image sensor for capturing blue, green and red light, another image sensor for capturing fluorescence light from protoporphyrin and indocyanine green, and a beam splitter for guiding light from the object that has a wavelength shorter than a predetermined threshold wavelength ?0 to the first image sensor, and for guiding light from the object that has a wavelength longer than the predetermined threshold wavelength ?0 to the second image sensor. A filter arranged upstream of the second image sensor partially, extensively or completely suppresses light at a wavelength suitable for exciting fluorescence of indocyanine green. A corresponding method is also presented.

Abstract: A device for capturing an image of an object of medical interest in remitted or reflected illumination light and for capturing an image of the object in fluorescent light generated by Cy5.5 and/or SGM-101 and for capturing an image in fluorescent light generated OTL38 and/or indocyanine green (ICG). The device includes an image sensor for detecting blue, green and red light, another image sensor for detecting fluorescent light of Cy5.5 and/or SGM-101 and OTL38 and/or ICG, a beam splitter guiding light having a wavelength smaller than a predetermined cutoff wavelength to the first sensor and guiding light having a wavelength greater than the predetermined cutoff wavelength to the second sensor, and filters upstream of the second sensor for partially, substantially or completely suppressing light having a wavelength exciting Cy5.5 and/or SGM-101 and for partially, substantially or completely suppressing light having a wavelength suitable for exciting fluorescence of OTL38 and/or ICG.

Abstract: An optical filter system and a video endoscope therefor are disclosed. The optical filter system is arranged in a distal end section of a shaft. At least one image sensor for receiving image light is positioned in the distal end section. The optical filter system contains an optical filter and an objective lens system with a three or more lenses to collect image light and to pass it to the image sensor. The filter has transmission characteristics that vary relative to the radial distance from its center and is located between the first lens and the second lens of the objective lens system. Used in conjunction with fluorescence imaging, emission radiation collected by the image sensor is substantially free of excitation radiation. Additionally, a display system clearly delineating the regions with reliable fluorescence and/or visible light is also disclosed.

Abstract: A device for capturing an image of an object of medical interest in remitted or reflected illumination light and for capturing an image of the object in fluorescent light generated by Cy5.5 and/or SGM-101 and for capturing an image in fluorescent light generated OTL38 and/or indocyanine green (ICG). The device includes an image sensor for detecting blue, green and red light, another image sensor for detecting fluorescent light of Cy5.5 and/or SGM-101 and OTL38 and/or ICG, a beam splitter guiding light having a wavelength smaller than a predetermined cutoff wavelength to the first sensor and guiding light having a wavelength greater than the predetermined cutoff wavelength to the second sensor, and filters upstream of the second sensor for partially, substantially or completely suppressing light having a wavelength exciting Cy5.5 and/or SGM-101 and for partially, substantially or completely suppressing light having a wavelength suitable for exciting fluorescence of OTL38 and/or ICG.

Abstract: Improved fluorescent imaging and other sensor data imaging processes, including hyperspectral imaging, devices, and systems are provided to enhance endoscopes with multiple wavelength capabilities and providing sequential imaging and display. A first optical device is provided for endoscopy imaging in a white light and a fluoresced light mode with an imaging unit including one or more image sensors. A mechanism in the first optical device to automatically adjust the focus of the first optical device using one or more deformable, variable-focus lenses, wherein the automatic focus adjustment compensates for a chromatic focal difference between the light collected at distinct wavelength bands caused by the dispersive or diffractive properties of the optical materials or optical design employed in the construction of the first or second optical devices, or both. Further variable spectrum imaging is enhanced with the use of adjustable spectral filters.

Abstract: Improved fluorescent imaging and other sensor data imaging processes, including hyperspectral imaging, devices, and systems are provided to enhance endoscopes with multiple wavelength capabilities and providing sequential imaging and display. A first optical device is provided for endoscopy imaging in a white light and a fluoresced light mode with an imaging unit including one or more image sensors. A mechanism in the first optical device to automatically adjust the focus of the first optical device using one or more deformable, variable-focus lenses, wherein the automatic focus adjustment compensates for a chromatic focal difference between the light collected at distinct wavelength bands caused by the dispersive or diffractive properties of the optical materials or optical design employed in the construction of the first or second optical devices, or both. Further variable spectrum imaging is enhanced with the use of adjustable spectral filters.

Abstract: Improved fluorescent imaging and other sensor data imaging processes, including hyperspectral imaging, devices, and systems are provided to enhance endoscopes with multiple wavelength capabilities and providing sequential imaging and display. A first optical device is provided for endoscopy imaging in a white light and a fluoresced light mode with an imaging unit including one or more image sensors. A mechanism in the first optical device to automatically adjust the focus of the first optical device using one or more deformable, variable-focus lenses, wherein the automatic focus adjustment compensates for a chromatic focal difference between the light collected at distinct wavelength bands caused by the dispersive or diffractive properties of the optical materials or optical design employed in the construction of the first or second optical devices, or both. Further variable spectrum imaging is enhanced with the use of adjustable spectral filters.

Abstract: An image capture apparatus for capturing an image of an object of medical interest in reemitted and/or reflected illumination light, for capturing an image of the object in fluorescence light generated by protoporphyrin, and for capturing an image in fluorescence light generated by OTL38. The apparatus includes an image sensor for capturing blue, green and red light, another image sensor for capturing fluorescence light from protoporphyrin and OTL38, and a beam splitter for guiding light from the object that has a wavelength shorter than a predetermined threshold wavelength ?0 to the first image sensor, and for guiding light from the object that has a wavelength longer than the predetermined threshold wavelength ?0 to the second image sensor. A filter arranged upstream of the second image sensor partially, extensively or completely suppresses light at a wavelength suitable for exciting fluorescence of OTL38. A corresponding method is also presented.

Abstract: An image capture apparatus for capturing an image of an object of medical interest in reemitted and/or reflected illumination light, for capturing an image of the object in fluorescence light generated by protoporphyrin, and for capturing an image in fluorescence light generated by indocyanine green. The apparatus includes an image sensor for capturing blue, green and red light, another image sensor for capturing fluorescence light from protoporphyrin and indocyanine green, and a beam splitter for guiding light from the object that has a wavelength shorter than a predetermined threshold wavelength ?0 to the first image sensor, and for guiding light from the object that has a wavelength longer than the predetermined threshold wavelength ?0 to the second image sensor. A filter arranged upstream of the second image sensor partially, extensively or completely suppresses light at a wavelength suitable for exciting fluorescence of indocyanine green. A corresponding method is also presented.

Abstract: A device for capturing an image of an object of medical interest in remitted or reflected illumination light and for capturing an image of the object in fluorescent light generated by Cy5.5 and/or SGM-101 and for capturing an image in fluorescent light generated OTL38 and/or indocyanine green (ICG). The device includes an image sensor for detecting blue, green and red light, another image sensor for detecting fluorescent light of Cy5.5 and/or SGM-101 and OTL38 and/or ICG, a beam splitter guiding light having a wavelength smaller than a predetermined cutoff wavelength to the first sensor and guiding light having a wavelength greater than the predetermined cutoff wavelength to the second sensor, and filters upstream of the second sensor for partially, substantially or completely suppressing light having a wavelength exciting Cy5.5 and/or SGM-101 and for partially, substantially or completely suppressing light having a wavelength suitable for exciting fluorescence of OTL38 and/or ICG.

Abstract: An optical filter system and a video endoscope therefor are disclosed. The optical filter system is arranged in a distal end section of a shaft. At least one image sensor for receiving image light is positioned in the distal end section. The optical filter system contains an optical filter and an objective lens system with a three or more lenses to collect image light and to pass it to the image sensor. The filter has transmission characteristics that vary relative to the radial distance from its center and is located between the first lens and the second lens of the objective lens system. Used in conjunction with fluorescence imaging, emission radiation collected by the image sensor is substantially free of excitation radiation. Additionally, a display system clearly delineating the regions with reliable fluorescence and/or visible light is also disclosed.

Abstract: Improved fluorescent imaging and other sensor data imaging processes, including hyperspectral imaging, devices, and systems are provided to enhance endoscopes with multiple wavelength capabilities and providing sequential imaging and display. A first optical device is provided for endoscopy imaging in a white light and a fluoresced light mode with an imaging unit including one or more image sensors. A mechanism in the first optical device to automatically adjust the focus of the first optical device using one or more deformable, variable-focus lenses, wherein the automatic focus adjustment compensates for a chromatic focal difference between the light collected at distinct wavelength bands caused by the dispersive or diffractive properties of the optical materials or optical design employed in the construction of the first or second optical devices, or both. Further variable spectrum imaging is enhanced with the use of adjustable spectral filters.