Abstract: Methods and apparatus for application-to-application resource reservation schemes for precision networking. Hardware resources, such as interconnects and processing resources, are reserved for forwarding and processing data along flow paths for end-to-end delivery of data between applications running on respective platforms communicating over a network. Operating system and/or hypervisor resources are also reserved. The reservations may be based per application, per virtual machine (VM), or per container, and reservations for multiple applications/VMs/containers are supported. The interconnects include chip-to-chip, socket-to-socket (for multi-socket platforms), and die-to-die interconnects. Reservations for on-chip fabrics are also supported.