Patents by Inventor Christina Galonska

Christina Galonska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for spatial analysis using RNA-templated ligation
    Patent number: 11505828
    Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.
    Type: Grant
    Filed: April 1, 2021
    Date of Patent: November 22, 2022
    Assignee: 10x Genomics, Inc.
    Inventors: James Michael Chell, Marlon Stoeckius, Jonathan Alles, Caroline Julie Gallant, Christina Galonska, Layla Katiraee
  • METHODS FOR SPATIAL ANALYSIS USING RNA-TEMPLATED LIGATION
    Publication number: 20220282329
    Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.
    Type: Application
    Filed: March 29, 2022
    Publication date: September 8, 2022
    Inventors: James Michael Chell, Marlon Stoeckius, Jonathan Alles, Caroline Julie Gallant, Christina Galonska, Felice Alessio Bava, Layla Katiraee
  • Spatial analysis of DNA methylation
    Patent number: 11408029
    Abstract: Provided herein are methods of identifying a methylation status of an analyte in a biological sample. Also provided herein are methods that combine identifying the methylation status with spatial technology to identify the location of a methylation status in a biological sample.
    Type: Grant
    Filed: January 11, 2022
    Date of Patent: August 9, 2022
    Assignee: 10x Genomics, Inc.
    Inventors: Layla Katiraee, Michael Schnall-Levin, Christina Galonska, Marlon Stoeckius
  • Methods for spatial analysis using RNA-templated ligation
    Patent number: 11332790
    Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.
    Type: Grant
    Filed: April 1, 2021
    Date of Patent: May 17, 2022
    Assignee: 10x Genomics, Inc.
    Inventors: James Michael Chell, Marlon Stoeckius, Jonathan Alles, Caroline Julie Gallant, Christina Galonska, Felice Alessio Bava, Layla Katiraee
  • NOVEL HIGH FIDELITY RNA-PROGRAMMABLE ENDONUCLEASE SYSTEMS AND USES THEREOF
    Publication number: 20220145274
    Abstract: Described herein are novel systems for targeting, editing or manipulating DNA in a cell, using novel M-SmallCas9 nucleases and variants thereof. The M-SmallCas9 nucleases are derived from wildtype or parental small type II CRISPR Cas9 endonucleases, and display improved fidelity compared to parental type II CRISPR Cas9 enzymes in combination with a simple PAM sequences and are small endonuclease size.
    Type: Application
    Filed: March 12, 2020
    Publication date: May 12, 2022
    Inventors: Moritz Schmidt, Philipp Knyphausen, Christina Galonska, Wayne Coco, Andre Cohnen
  • SPATIAL ANALYSIS OF DNA METHYLATION
    Publication number: 20220127666
    Abstract: Provided herein are methods of identifying a methylation status of an analyte in a biological sample. Also provided herein are methods that combine identifying the methylation status with spatial technology to identify the location of a methylation status in a biological sample.
    Type: Application
    Filed: January 11, 2022
    Publication date: April 28, 2022
    Inventors: Layla Katiraee, Michael Schnall-Levin, Christina Galonska, Marlon Stoeckius
  • SPATIAL ANALYSIS TO DETECT SEQUENCE VARIANTS
    Publication number: 20220106632
    Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample.
    Type: Application
    Filed: December 15, 2021
    Publication date: April 7, 2022
    Inventors: Christina Galonska, Marco Mignardi
  • METHODS FOR SPATIAL ANALYSIS USING RNA-TEMPLATED LIGATION
    Publication number: 20210348221
    Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.
    Type: Application
    Filed: April 1, 2021
    Publication date: November 11, 2021
    Inventors: James Michael Chell, Marlon Stoeckius, Jonathan Alles, Caroline Julie Gallant, Christina Galonska, Felice Alessio Bava, Layla Katiraee
  • METHODS FOR SPATIAL ANALYSIS USING RNA-TEMPLATED LIGATION
    Publication number: 20210285046
    Abstract: Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.
    Type: Application
    Filed: April 1, 2021
    Publication date: September 16, 2021
    Inventors: James Michael Chell, Marlon Stoeckius, Jonathan Alles, Caroline Julie Gallant, Christina Galonska, Felice Alessio Bava, Layla Katiraee