Patents by Inventor Christina H. Chiang

Christina H. Chiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL RECOMBINANT AND MUTANT ADENOVIRUSES
    Publication number: 20090274724
    Abstract: The present invention provides novel viral vectors. In one embodiment, the present invention provides mutant and recombinant bovine adenoviruses having a deletion and/or insertion of DNA in the early gene region 4 (E4). In another embodiment, the present invention provides mutant and recombinant bovine adenovirus 1 viruses having a deletion and/or insertion of DNA in the early gene region 3 (E3). The present invention also contemplates the use of the viral vectors for vaccination, gene therapy or other applications as suitable.
    Type: Application
    Filed: June 23, 2009
    Publication date: November 5, 2009
    Inventors: Christina H. Chiang, Mark D. Cochran
  • Novel recombinant and mutant adenoviruses
    Publication number: 20040234549
    Abstract: The present invention provides novel viral vectors. In one embodiment, the present invention provides mutant and recombinant bovine adenoviruses having a deletion and/or insertion of DNA in the early gene region 4 (E4). In another embodiment, the present invention provides mutant and recombinant bovine adenovirus 1 viruses having a deletion and/or insertion of DNA in the early gene region 3 (E3). The present invention also contemplates the use of the viral vectors for vaccination, gene therapy or other applications as suitable.
    Type: Application
    Filed: June 23, 2004
    Publication date: November 25, 2004
    Inventors: Christina H. Chiang, Mark D. Cochran
  • Novel recombinant and mutant adenoviruses
    Publication number: 20030108569
    Abstract: The present invention provides novel viral vectors. In one embodiment, the present invention provides mutant and recombinant bovine adenoviruses having a deletion and/or insertion of DNA in the early gene region 4 (E4). In another embodiment, the present invention provides mutant and recombinant bovine adenovirus 1 viruses having a deletion and/or insertion of DNA in the early gene region 3 (E3). The present invention also contemplates the use of the viral vectors for vaccination, gene therapy or other applications as suitable.
    Type: Application
    Filed: July 19, 2002
    Publication date: June 12, 2003
    Inventors: Christina H. Chiang, Mark D. Cochran
  • Recombinant and mutant adenoviruses
    Patent number: 6451319
    Abstract: The present invention provides novel viral vectors. In one embodiment, the present invention provides mutant and recombinant bovine adenoviruses having a deletion and/or insertion of DNA in the early gene region 4 (E4). In another embodiment, the present invention provides mutant and recombinant bovine adenovirus 1 viruses having a deletion and/or insertion of DNA in the early gene region 3 (E3). The present invention also contemplates the use of the viral vectors for vaccination, gene therapy or other applications as suitable.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: September 17, 2002
    Assignee: Schering-Plough Veterinary Corporation
    Inventors: Christina H. Chiang, Mark D. Cochran
  • Recombinant equine herpesviruses
    Patent number: 6225111
    Abstract: The present invention relates to a non-naturally occurring, recombinant equine herpesvirus. The invention also relates to a recombinant equine herpesvirus capable of replication which comprises viral DNA from a species of equine herpesvirus and foreign DNA, the foreign DNA being inserted into the equine herpesviral DNA at a site which is not essential for replication of the equine herpesvirus. The invention also relates to DNA encoding the US2 protein of an equine herpesvirus. The invention relates to homology vectors for producing recombinant equine herpesviruses which produce recombinant equine herpesviruses by inserting foreign DNA into equine herpesviral DNA. The invention further relates to a method of producing a fetal-safe, live recombinant equine herpesvirus.
    Type: Grant
    Filed: August 3, 1995
    Date of Patent: May 1, 2001
    Assignee: Schering Plough Veterinary Corp.
    Inventors: Mark D. Cochran, Christina H. Chiang
  • Recombinant equine herpesviruses
    Patent number: 5741696
    Abstract: The present invention relates to a non-naturally occurring, recombinant equine herpesvirus. The invention also relates to a recombinant equine herpesvirus capable of replication which comprises viral DNA from a species of equine herpesvirus and foreign DNA, the foreign DNA being inserted into the equine herpesviral DNA at a site which is not essential for replication of the equine herpesvirus. The invention also relates to DNA encoding the US2 protein of an equine herpesvirus. The invention relates to homology vectors for producing recombinant equine herpesviruses which produce recombinant equine herpesviruses by inserting foreign DNA into equine herpesviral DNA. The invention further relates to a method of producing a fetal-safe, live recombinant equine herpesvirus.
    Type: Grant
    Filed: February 17, 1994
    Date of Patent: April 21, 1998
    Assignee: Syntro Corporation
    Inventors: Mark D. Cochran, Christina H. Chiang
  • Recombinant equine herpesviruses
    Patent number: 5731188
    Abstract: The present invention relates to a non-naturally occurring, recombinant equine herpesvirus. The invention also relates to a recombinant equine herpesvirus capable of replication which comprises viral DNA from a species of equine herpesvirus and foreign DNA, the foreign DNA being inserted into the equine herpesviral DNA at a site which is not essential for replication of the equine herpesvirus. The invention also relates to DNA encoding the US2 protein of an equine herpesvirus. The invention relates to homology vectors for producing recombinant equine herpesviruses which produce recombinant equine herpesviruses by inserting foreign DNA into equine herpesviral DNA. The invention further relates to a method of producing a fetal-safe, live recombinant equine herpesvirus.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: March 24, 1998
    Assignee: Syntro Corporation
    Inventors: Mark D. Cochran, Christina H. Chiang
  • Recombinant infectious bovine rhinotracheitis virus
    Patent number: 5506128
    Abstract: The present invention provides a recombinant infectious bovine rhinotracheitis virus which is characterized by an insertion of an expressible foreign DNA sequence encoding a polypeptide into the BamHI C fragment of the infectious bovine rhinotracheitis virus genome.
    Type: Grant
    Filed: June 17, 1993
    Date of Patent: April 9, 1996
    Assignee: PruTech Research and Development Partnership
    Inventors: Mark D. Cochran, Christina H. Chiang, Richard D. MacDonald
  • Attenuated herpesviruses and herpesviruses which include foreign DNA encoding an amino acid sequence
    Patent number: 5223424
    Abstract: The present invention provides a recombinant fusion protein comprising an antigenic amino acid sequence fused to at least a portion of the gpX glycoprotein from pseudorabies virus. Such a protein may be formulated into a vaccine and delivered to an animal using a live herpesvirus vector adapted to express the fusion protein.
    Type: Grant
    Filed: July 27, 1988
    Date of Patent: June 29, 1993
    Assignee: Prutech Research And Development
    Inventors: Mark D. Cochran, Christina H. Chiang, Richard D. MacDonald