Patents by Inventor Christina Lowes
Christina Lowes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10677802Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of binding at least one probe to one or more target present in a biological sample including multiple targets, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a photoinitiator and irradiating the sample, thereby initiating a photoactivated chemical bleaching process that substantially inactivates the probe. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, detecting and bleaching may be iteratively repeated.Type: GrantFiled: November 19, 2013Date of Patent: June 9, 2020Assignee: GE Healthcare Bio-Sciences Corp.Inventors: Anup Sood, Arunkumar Natarajan, Lakshmi Sireesha Kaanumalle, Christina Lowes
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Patent number: 10175174Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample including multiple targets, binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with an electron transfer reagent, as well as an optional additive which prevents target modification during photoactivated chemical bleaching, and irradiating the sample, thereby initiating a photoreaction that substantially inactivates the probe by photoactivated chemical bleaching. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, defecting and bleaching may be iteratively repeated.Type: GrantFiled: December 11, 2013Date of Patent: January 8, 2019Assignee: GE HEALTHCARE BIO-SCIENCES CORP.Inventors: Arunkumar Natarajan, Robert John Filkins, Anup Sood, Lakshmi Sireesha Kaanumalle, Kashan Ali Shaikh, Christina Lowes
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Patent number: 10101322Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample containing multiple targets, binding at least one probe to one or more target present in the sample, and observing a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a cationic or zwitterionic borate compound and irradiating the sample, thereby initiating a photoreaction that substantially inactivates the probe by photoactivated chemical bleaching. The method further includes the steps of binding at least one probe to one or more target present in the sample, and observing a signal from the probe. The process of binding, observing and bleaching may be iteratively repeated.Type: GrantFiled: February 13, 2015Date of Patent: October 16, 2018Assignee: GENERAL ELECTRIC COMPANYInventors: Arunkumar Natarajan, Anup Sood, Lakshmi Sireesha Kaanumalle, Christina Lowes
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Patent number: 9814343Abstract: The invention relates to a water drawer (1), comprising a housing element (2) and a drawer element (3), wherein the drawer element (3) is movably guided within the housing element (2) and wherein water can be filled into a water receiving space of the drawer element (3), wherein the drawer element (3) can be moved in a translational movement between a first inner position (IN) and a second outer position (OUT), characterized in that the water drawer (1) further comprises at least one driving element (16) for providing a driving force for driving the drawer element (3) to move into the second outer position (OUT).Type: GrantFiled: July 16, 2012Date of Patent: November 14, 2017Assignee: Electrolux Home Products CorporationInventors: Klaus Winkelmann, Wolfgang Kraus, Christina Lowe, Lorenzo Gattei, Marco Saporetti
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Publication number: 20160238592Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample containing multiple targets, binding at least one probe to one or more target present in the sample, and observing a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a cationic or zwitterionic borate compound and irradiating the sample, thereby initiating a photoreaction that substantially inactivates the probe by photoactivated chemical bleaching. The method further includes the steps of binding at least one probe to one or more target present in the sample, and observing a signal from the probe. The process of binding, observing and bleaching may be iteratively repeated.Type: ApplicationFiled: February 13, 2015Publication date: August 18, 2016Inventors: Arunkumar Natarajan, Anup Sood, Lakshmi Sireesha Kaanumalle, Christina Lowes
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Publication number: 20150316482Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample including multiple targets, binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with an electron transfer reagent, as well as an optional additive which prevents target modification during photoactivated chemical bleaching, and irradiating the sample, thereby initiating a photoreaction that substantially inactivates the probe by photoactivated chemical bleaching. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, defecting and bleaching may be iteratively repeated.Type: ApplicationFiled: December 11, 2013Publication date: November 5, 2015Inventors: Arunkumar Natarajan, Robert John Filkins, Anup Sood, Lakshmi Sireesha Kaanumalle, Kashan Ali Shaikh, Christina Lowes
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Publication number: 20150285813Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of binding at least one probe to one or more target present in a biological sample including multiple targets, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a photoinitiator and irradiating the sample, thereby initiating a photoactivated chemical bleaching process that substantially inactivates the probe. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, detecting and bleaching may be iteratively repeated.Type: ApplicationFiled: November 19, 2013Publication date: October 8, 2015Inventors: Anup Sood, Arunkumar Natarajan, Lakshmi Sireesha Kaanumalle, Christina Lowes
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Publication number: 20140251304Abstract: The invention relates to a water drawer (1), comprising a housing element (2) and a drawer element (3), wherein the drawer element (3) is movably guided within the housing element (2) and wherein water can be filled into a water receiving space of the drawer element (3), wherein the drawer element (3) can be moved in a translational movement between a first inner position (IN) and a second outer position (OUT), characterized in that the water drawer (1) further comprises at least one driving element (16) for providing a driving force for driving the drawer element (3) to move into the second outer position (OUT).Type: ApplicationFiled: July 16, 2012Publication date: September 11, 2014Applicant: ELECTROLUX HOME PRODUCTS CORPORATION N.V.Inventors: Klaus Winkelmann, Wolfgang Kraus, Christina Lowe, Lorenzo Gattei, Marco Saporetti