Patents by Inventor Christina Owens

Christina Owens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMIDAZOLO INDAZOLE COMPOUNDS AS JAK INHIBITORS
    Publication number: 20240092758
    Abstract: Provided herein are compounds of formula (I): and pharmaceutically-acceptable salts thereof, where A, W, X, Y and Z are defined in the specification. The compounds of formula (I) and pharmaceutically-acceptable salts thereof are Janus kinase (JAK) inhibitors. Also provided herein are pharmaceutical compositions comprising such compounds; and methods of using such compounds to treat, e.g., inflammatory and fibrotic diseases, including respiratory diseases.
    Type: Application
    Filed: June 24, 2022
    Publication date: March 21, 2024
    Inventors: Robert Murray MCKINNELL, Tom M. LAM, Cameron SMITH, Philip GERKEN, Paul ALLEGRETTI, Gabrielle Elaine DOLGONOS, Christina OWENS
  • ALK5 inhibitors
    Patent number: 11730720
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: August 22, 2023
    Assignee: Theravance Biopharma R&D IP, LLC
    Inventors: Svitlana Kulyk, Christina Owens, Steven D. E. Sullivan, Jennifer Kozak, Adam D. Hughes
  • SUBSTITUTED PYRIDINES AND METHODS OF USE
    Publication number: 20230218597
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Application
    Filed: January 4, 2023
    Publication date: July 13, 2023
    Inventors: Christina Owens, Svitlana Kulyk, Steven D.E. Sullivan, Paul Allegretti, Mandy Loo, Jennifer Kozak, Chen Zhao, Erik Fenster, Adam D. Hughes
  • Substituted pyridines and methods of use
    Patent number: 11590116
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: February 28, 2023
    Assignee: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Christina Owens, Svitlana Kulyk, Steven D. E. Sullivan, Paul Allegretti, Mandy Loo, Jennifer Kozak, Erik Fenster, Adam D. Hughes
  • SUBSTITUTED PYRIDINES AND METHODS OF USE
    Publication number: 20210154179
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 27, 2021
    Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Christina Owens, Svitlana Kulyk, Steven D.E. Sullivan, Paul Allegretti, Mandy Loo, Jennifer Kozak, Erik Fenster, Adam D. Hughes
  • ALK5 INHIBITORS
    Publication number: 20210154178
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Application
    Filed: December 4, 2020
    Publication date: May 27, 2021
    Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Svitlana Kulyk, Christina Owens, Steven D.E. Sullivan, Jennifer Kozak, Adam D. Hughes
  • ALK5 inhibitors
    Patent number: 10952996
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: March 23, 2021
    Assignee: Theravance Biopharma R&D IP, LLC
    Inventors: Svitlana Kulyk, Christina Owens, Steven D. E. Sullivan, Jennifer Kozak, Adam D. Hughes
  • ALK5 INHIBITORS
    Publication number: 20200188370
    Abstract: The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 18, 2020
    Applicant: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Svitlana Kulyk, Christina Owens, Steven D.E. Sullivan, Jennifer Kozak, Adam D. Hughes