Patents by Inventor Christina Yi

Christina Yi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Determining small molecule-protein and protein-protein interactions
    Patent number: 11912664
    Abstract: Provided herein are methods, systems, kits, and compositions useful for determining small molecule-protein interactions and protein-protein interactions. The photo-click tags provided herein can be conjugated to a small molecule or amino acid analog to provide compounds that can be integrated into a protein through photo-conjugation, allowing for identification of a small molecule-protein interaction or protein-protein interaction to elucidate the small molecules mechanism of action or the protein targeted by the small molecule. In some embodiments, the photo-click tags comprise a photo-conjugation moiety and a click chemistry handle, allowing for the attachment of various functional groups (e.g., affinity tags) to the small molecule or amino acid analog.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: February 27, 2024
    Assignee: President and Fellows of Harvard College
    Inventors: Christina M. Woo, Jinxu Gao, Yuka Amako, Chia Fu Chang, Zhi Lin, Hung-Yi Wu
  • Method for producing polypeptides using PDK-inactivated cells
    Patent number: 10202456
    Abstract: Provided is a recombinant cell including inactivated pyruvate dehydrogenase kinase (PDK) gene, a composition for producing a polypeptide of interest including the recombinant cell, and a method of producing a polypeptide of interest using the recombinant cell.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: February 12, 2019
    Assignee: Samsung Bioepis Co., Ltd.
    Inventors: Eunyoung Park, Hye Young Suh, Hee Kyung Sung, Christina Yi, Sunkyu Kim
  • Bispecific anti-Cmet/anti-Her2 antibodies
    Patent number: 10143749
    Abstract: There are provided an anti-c-Met/anti-Her2 bispecific antibody, and a method for preventing and/or treating cancer using the same.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: December 4, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mi Young Cho, Powei Lin, Seung Hyun Lee, Kwang Ho Cheong, Young Jun Koh, Christina Yi, Jae Woong Hwang
  • Anti-c-Met/anti-EGFR bispecific antibodies
    Patent number: 9657104
    Abstract: There are provided an anti-c-Met/anti-EGFR bispecific antibody, a method for treating cancer using the same, and an anti-EGFR scFv fragment.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: May 23, 2017
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mi Young Cho, Seung Hyun Lee, Kwang Ho Cheong, Powei Lin, Jae Woong Hwang, Christina Yi, Young Jun Koh
  • Method of target membrane protein depletion
    Patent number: 9388243
    Abstract: A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: July 12, 2016
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Kwang Ho Cheong, Seung Hyun Lee, Mi Young Cho, Young Jun Koh, Lin Powei, Christina Yi, Jae Woong Hwang
  • METHOD FOR PRODUCING POLYPEPTIDES USING PDK-INACTIVATED CELLS
    Publication number: 20160130364
    Abstract: Provided is a recombinant cell including inactivated pyruvate dehydrogenase kinase (PDK) gene, a composition for producing a polypeptide of interest including the recombinant cell, and a method of producing a polypeptide of interest using the recombinant cell.
    Type: Application
    Filed: November 2, 2015
    Publication date: May 12, 2016
    Inventors: Eunyoung PARK, Hye Young SUH, Hee Kyung SUNG, Christina YI, Sunkyu KIM
  • Antibodies to EphA3
    Patent number: 9290571
    Abstract: The current invention relates to high-affinity antibodies to EphA3 that have reduced immunogenicity when administered to a human to treat diseases and method of using such antibodies.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: March 22, 2016
    Assignee: KaloBios Pharmaceuticals, Inc.
    Inventors: Kenneth Luehrsen, David Martinez, Christina Yi, Christopher R. Bebbington, Geoffrey T. Yarranton
  • COMPOSITION FOR TARGET MEMBRANE PROTEIN DEPLETION
    Publication number: 20140356366
    Abstract: A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.
    Type: Application
    Filed: May 29, 2014
    Publication date: December 4, 2014
    Applicant: Samsung Electronics Co., Ltd.
    Inventors: Kwang Ho CHEONG, Seung Hyun Lee, Mi Young Cho, Young Jun Koh, Lin Powei, Christina Yi, Jae Woong Hwang
  • ANTI-C-MET/ANTI-EGFR BISPECIFIC ANTIBODIES
    Publication number: 20140302029
    Abstract: There are provided an anti-c-Met/anti-EGFR bispecific antibody, a method for preventing and/or treating cancer using the same, and an anti-EGFR scFv fragment.
    Type: Application
    Filed: March 31, 2014
    Publication date: October 9, 2014
    Inventors: MI YOUNG CHO, SEUNG HYUN LEE, KWANG HO CHEONG, POWEI LIN, JAE WOONG HWANG, CHRISTINA YI, YOUNG JUN KOH
  • BISPECIFIC ANTI-CMET/ANTI-HER2 ANTIBODIES
    Publication number: 20140294838
    Abstract: There are provided an anti-c-Met/anti-Her2 bispecific antibody, and a method for preventing and/or treating cancer using the same.
    Type: Application
    Filed: March 28, 2014
    Publication date: October 2, 2014
    Applicant: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Mi Young CHO, Powei Lin, Seung Hyun Lee, Kwang Ho Cheong, Young Jun Koh, Christina Yi, Jae Woong Hwang
  • Antibodies to EphA3
    Publication number: 20140120114
    Abstract: The current invention relates to high-affinity antibodies to EphA3 that have reduced immunogenicity when administered to a human to treat diseases and method of using such antibodies.
    Type: Application
    Filed: December 30, 2013
    Publication date: May 1, 2014
    Applicant: KALOBIOS PHARMACEUTICALS, INC.
    Inventors: Kenneth Luehrsen, David Martinez, Christina Yi, Christopher R. Bebbington, Geoffrey T. Yarranton
  • Antibodies to EphA3
    Patent number: 8664365
    Abstract: The current invention relates to high-affinity antibodies to EphA3 that have reduced immunogenicity when administered to a human to treat diseases and method of using such antibodies.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: March 4, 2014
    Assignee: KaloBios Pharmaceuticals, Inc.
    Inventors: Kenneth Luehrsen, David Martinez, Christina Yi, Christopher R. Bebbington, Geoffrey T. Yarranton
  • Antibodies to EphA3
    Publication number: 20110123549
    Abstract: The current invention relates to high-affinity antibodies to EphA3 that have reduced immunogenicity when administered to a human to treat diseases and method of using such antibodies.
    Type: Application
    Filed: October 14, 2010
    Publication date: May 26, 2011
    Applicant: KaloBios Pharmaceuticals, Inc.
    Inventors: Kenneth Luehrsen, David Martinez, Christina Yi, Christopher R. Bebbington, Geoffrey T. Yarranton