Patents by Inventor Christine Bruun Schiødt

Christine Bruun Schiødt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fatty Acid Acylated Amino Acids for Growth Hormone Delivery
    Publication number: 20150250882
    Abstract: The present invention relates to growth hormone compositions comprising a fatty acid acylated amino acids (FA-aa's), which may be used in pharmaceutical compositions such as pharmaceutical compositions for oral administration of growth hormone.
    Type: Application
    Filed: October 17, 2013
    Publication date: September 10, 2015
    Inventors: Mats Reslow, Leif Noerskov-Lauritsen, Heidi Westh Bagger, Christine Bruun Schioedt
  • Polypeptide protracting tags
    Patent number: 9061067
    Abstract: The invention relates to methods for increasing the plasma half-life of a molecule, such as human growth hormone, comprising covalently linking the molecule to a heterocyclic carboxylic acid bioisostere.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: June 23, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Florencio Zaragoza Dörwald, Christine Bruun Schiødt, Thomas Kruse Hansen, Kjeld Madsen
  • Stable growth hormone compounds resistant to proteolytic degradation
    Patent number: 8513192
    Abstract: The present invention relates to stable growth hormone (GH) compounds, which through the introduction of cysteine residues have disulphide bridges, which make the compounds resistant to proteolytic degradation.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: August 20, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Ole Hvilsted Olsen, Jens Breinholt, Christine Bruun Schiødt, Helle Demuth, Leif Nørskov-Lauritsen, Peter Thygesen
  • GROWTH HORMONE CONJUGATES
    Publication number: 20130143815
    Abstract: The present invention relates to growth hormone conjugates comprising a bile acid residue, said conjugation may occur through wt or mutant amino acid residues. The growth hormone polypeptide may be wt human growth hormone or a growth hormone variant.
    Type: Application
    Filed: July 15, 2011
    Publication date: June 6, 2013
    Applicant: NOVO NORDISK HEALTH CARE AG
    Inventors: Henrik Sune Andersen, Kjeld Madsen, Helle Demuth, Christine Bruun Schioedt, Leif Noerskov-Lauritsen, Peter Thygesen, Carsten Behrens, Mette Guldbrandt
  • IL-21 derivatives and variants
    Patent number: 8450459
    Abstract: The invention provides derivatives of IL-21 or variants thereof, methods of producing such variants, new variants of IL-21, and various methods of using such molecules.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: May 28, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Bernd Peschke, Christine Bruun Schiødt, Helle Wöldike, Florencio Zaragoza Dörwald, Anne Worsaae
  • PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS
    Publication number: 20120116027
    Abstract: The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of Growth Hormone from closely related proteins.
    Type: Application
    Filed: November 13, 2009
    Publication date: May 10, 2012
    Inventors: Jakob Ewald Rasmussen, Phaedria Marie St. Hilaire, Michael Roice, Christine Bruun Schioedt, Knud Jørgen Jensen
  • Polypeptide Protracting Tags
    Publication number: 20120088716
    Abstract: Method for increasing half-life of compounds in plasma and novel derivatives of such compounds.
    Type: Application
    Filed: December 15, 2011
    Publication date: April 12, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Florencio Zaragoza Dörwald, Christine Bruun Schiødt, Thomas Kruse Hansen, Kjeld Madsen
  • STABLE GROWTH HORMONE COMPOUNDS
    Publication number: 20110306548
    Abstract: The present invention relates to stable growth hormone (GH) compounds, which through the introduction of cysteine residues have disulphide bridges, which make the compounds resistant to proteolytic degradation.
    Type: Application
    Filed: January 22, 2010
    Publication date: December 15, 2011
    Applicant: Novo Nordisk Health Care AG
    Inventors: Ole Hvilsted Olsen, Jens Breinholt, Christine Bruun Schiødt, Helle Demuth, Leif Nørskov-Lauritsen, Peter Thygesen
  • Expression of proteins in
    Patent number: 7858747
    Abstract: Plasmid comprising a DNA tag encoding a peptide tag of the sequence MX1(X2X3)n wherein X1 represents K, R or H; X2 represents A, G, H, M, S or T; X3 represents K, R, H, A, Q or V; n represents an integer of 1 or larger; and wherein said DNA is operably-linked to a promoter sequence are provided.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: December 28, 2010
    Assignee: Novo Nordisk A/S
    Inventors: Helle Fabricius Wöldike, Christine Bruun Schiødt