Patents by Inventor Christine Bruun Schiodt

Christine Bruun Schiodt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide protracting tags
    Patent number: 9061067
    Abstract: The invention relates to methods for increasing the plasma half-life of a molecule, such as human growth hormone, comprising covalently linking the molecule to a heterocyclic carboxylic acid bioisostere.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: June 23, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Florencio Zaragoza Dörwald, Christine Bruun Schiødt, Thomas Kruse Hansen, Kjeld Madsen
  • Stable growth hormone compounds resistant to proteolytic degradation
    Patent number: 8513192
    Abstract: The present invention relates to stable growth hormone (GH) compounds, which through the introduction of cysteine residues have disulphide bridges, which make the compounds resistant to proteolytic degradation.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: August 20, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Ole Hvilsted Olsen, Jens Breinholt, Christine Bruun Schiødt, Helle Demuth, Leif Nørskov-Lauritsen, Peter Thygesen
  • IL-21 derivatives and variants
    Patent number: 8450459
    Abstract: The invention provides derivatives of IL-21 or variants thereof, methods of producing such variants, new variants of IL-21, and various methods of using such molecules.
    Type: Grant
    Filed: August 12, 2008
    Date of Patent: May 28, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Bernd Peschke, Christine Bruun Schiødt, Helle Wöldike, Florencio Zaragoza Dörwald, Anne Worsaae
  • Polypeptide Protracting Tags
    Publication number: 20120088716
    Abstract: Method for increasing half-life of compounds in plasma and novel derivatives of such compounds.
    Type: Application
    Filed: December 15, 2011
    Publication date: April 12, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Florencio Zaragoza Dörwald, Christine Bruun Schiødt, Thomas Kruse Hansen, Kjeld Madsen
  • STABLE GROWTH HORMONE COMPOUNDS
    Publication number: 20110306548
    Abstract: The present invention relates to stable growth hormone (GH) compounds, which through the introduction of cysteine residues have disulphide bridges, which make the compounds resistant to proteolytic degradation.
    Type: Application
    Filed: January 22, 2010
    Publication date: December 15, 2011
    Applicant: Novo Nordisk Health Care AG
    Inventors: Ole Hvilsted Olsen, Jens Breinholt, Christine Bruun Schiødt, Helle Demuth, Leif Nørskov-Lauritsen, Peter Thygesen
  • Expression of proteins in
    Patent number: 7858747
    Abstract: Plasmid comprising a DNA tag encoding a peptide tag of the sequence MX1(X2X3)n wherein X1 represents K, R or H; X2 represents A, G, H, M, S or T; X3 represents K, R, H, A, Q or V; n represents an integer of 1 or larger; and wherein said DNA is operably-linked to a promoter sequence are provided.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: December 28, 2010
    Assignee: Novo Nordisk A/S
    Inventors: Helle Fabricius Wöldike, Christine Bruun Schiødt
  • Expression of Proteins in E. Coli
    Publication number: 20100041153
    Abstract: Plasmid comprising a DNA tag encoding a peptide tag of the sequence MX1(X 2X 3) n X 1 represents K or R; X 2 represents M, S or T; X 3 represents K or R; n represents an integer of 1 or larger; and wherein said DNA is operably-linked to a promoter sequence are provided.
    Type: Application
    Filed: February 22, 2008
    Publication date: February 18, 2010
    Applicant: NOVO NORDISK HEALTHCARE AG
    Inventors: Helle Woldike, Christine Bruun Schiodt
  • IL-21 Derivatives and Variants
    Publication number: 20090253864
    Abstract: The invention provides derivatives of IL-21 or variants thereof, methods of producing such variants, new variants of IL-21, and various methods of using such molecules.
    Type: Application
    Filed: August 12, 2008
    Publication date: October 8, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Bernd Peschke, Christine Bruun Schiodt, Helle Woldike, Florencio Zaragoza Dorwald, Anne Worsaae
  • Polypeptide protracting tags
    Publication number: 20090111730
    Abstract: Method for increasing (protracting) half-life of LGP analogs in plasma and novel derivatives of such peptides based on covalently linking them to a tetrazole moiety which acts as a carboxylic acid bioisostere.
    Type: Application
    Filed: June 21, 2005
    Publication date: April 30, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Florencio Zaragoza Dorwald, Christine Bruun Schiodt, Thomas Kruse Hansen, Kjeld Madsen
  • Expression of Proteins in E.Coli
    Publication number: 20090035821
    Abstract: Plasmid comprising a DNA tag encoding a peptide tag of the sequence MX1(X2X3)n wherein X1 represents K, R or H; X2 represents A, G, H, M, S or T; X3 represents K, R, H, A, Q or V; n represents an integer of 1 or larger; and wherein said DNA is operably-linked to a promoter sequence are provided.
    Type: Application
    Filed: August 30, 2006
    Publication date: February 5, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Helle Woldike, Christine Bruun Schiodt
  • NOVEL GLP-1 ANALOGUES LINKED TO ALBUMIN-LIKE AGENTS
    Publication number: 20090005312
    Abstract: Novel GLP-1 agonists which are protracted by coupling to a protraction protein.
    Type: Application
    Filed: August 6, 2008
    Publication date: January 1, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Thomas Kruse Hansen, Magali Zundel, Kjeld Madsen, Anne Svendsen, Christine Bruun Schiodt, Jesper Lau
  • Method for the Preparation of Oxime, Thiazolidine, Dithiane, Dithiolane, or Hydrazone Linked Analogues of Growth Hormone
    Publication number: 20080076700
    Abstract: A method for the production of conjugated growth hormone is provided, wherein a GH derived aldehyde or ketone is reacted with an alkoxyamine, hydrazine or 2-aminothiol compound at acid pH in the presence of a dipolar solvent.
    Type: Application
    Filed: October 18, 2005
    Publication date: March 27, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Florencio Zaragoza Dorwald, Christine Bruun Schiodt