Abstract: A clothing item for retaining, displaying, and allowing operation of a portable electronic device. The clothing item includes an article of clothing, such as a shirt, formed of a material. A generally rectangular clear plastic front is permanently affixed along two sides edges and a bottom edge to the material of the article of clothing by permanent means, such as by stitch lines, to form a pocket, the clear plastic front having a front facing surface and a rear facing surface, wherein at least one of the rear facing surface of the clear plastic front and the material of the shirt in the vicinity of the pocket have an anti-slip surface texture or property. Indicia, such as images and/or text are preferably located on the article of clothing in the vicinity of the pocket, which indicia is at least partially viewable through the clear plastic front.

Abstract: The invention discloses the first known function and biological activity of the hypothetical protein MGC14327, now designated cMAC, which is herein identified as an important controller of T-cell activation. It is contemplated herein that cMAC is a suitable drug target for the development of new therapeutics to treat cMAC-associated disorders. The invention relates to methods to treat said pathological conditions and to pharmaceutical compositions therefore. The pharmaceutical compositions comprise modulators with inhibitory or agonist effect on cMAC protein activity and/or cMAC gene expression. The invention also relates to methods to identify compounds with therapeutic usefulness to treat said pathological conditions, comprising identifying compounds that can inhibit or agonize cMAC protein activity and/or cMAC gene expression.