Patents by Inventor Christine COTICCHIA

Christine COTICCHIA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment and diagnosis of parkinson's disease using isolated and enriched populations of biofluid-derived extracellular vesicles
    Patent number: 11899024
    Abstract: The invention relates generally to a process for isolating subpopulations of EVs to identify biomarkers useful identifying, determining the progression of, and/or prognosing a disease, including a neurological disease. More particularly, the present invention relates to detection technology of various exosomal biomarkers including proteins, protein modifications, sugars, RNA, DNA, lipids, and metabolites, and combinations thereof.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: February 13, 2024
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Mia Sher, Erez Eitan, Christine Coticchia, Johan Karl Olov Skog, Robert Kitchen, Seth Yu
  • Methods of detecting renal transplant rejection using microvesicle nucleic acid biomarkers
    Patent number: 11891664
    Abstract: The invention relates generally to the use of microvesicle biomarkers such as nucleic acids, including nucleic acid signatures, and/or proteins for assessing a kidney transplant rejection in a patient. The invention further relates to assessing, and/or to monitoring kidney transplant rejection in patients who have received a renal transplant.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: February 6, 2024
    Assignees: Exosome Diagnostics, Inc., The Brigham and Women's Hospital
    Inventors: James Hurley, Christine Coticchia, Robert Kitchen, Vasisht Tadigotla, Johan Karl Olov Skog, Jamil Azzi
  • METHODS FOR ISOLATING AND ENRICHING POPULATIONS OF BIOFLUID-DERIVED EXTRACELLULAR VESICLES, AND METHODS OF USE THEREOF
    Publication number: 20200292561
    Abstract: The invention relates generally to a process for isolating subpopulations of EVs to identify biomarkers useful identifying, determining the progression of, and/or prognosing a disease, including a neurological disease. More particularly, the present invention relates to detection technology of various exosomal biomarkers including proteins, protein modifications, sugars, RNA, DNA, lipids, and metabolites, and combinations thereof.
    Type: Application
    Filed: July 12, 2018
    Publication date: September 17, 2020
    Applicant: Exosome Diagnostics, Inc.
    Inventors: Mia SHER, Erez EITAN, Christine COTICCHIA, Johan Karl Olov SKOG, Robert KITCHEN, Seth YU
  • MICROVESICLE NUCLEIC ACIDS AND/OR PROTEINS AND USES THEREOF AS MARKERS OF RENAL TRANSPLANT REJECTION
    Publication number: 20200199675
    Abstract: The invention relates generally to the use of microvesicle biomarkers such as nucleic acids, including nucleic acid signatures, and/or proteins for assessing a kidney transplant rejection in a patient. The invention further relates to assessing, and/or to monitoring kidney transplant rejection in patients who have received a renal transplant.
    Type: Application
    Filed: May 16, 2018
    Publication date: June 25, 2020
    Inventors: James HURLEY, Christine COTICCHIA, Robert KITCHEN, Vasisht TADIGOTLA, Johan Karl Olov SKOG, Jamil AZZI