Abstract: An androgynous fastener for autonomous robotic assembly of high performance structures is disclosed herein. The androgynous fastener is lightweight and facilitates assembly through simple actuation with large driver-positioning tolerance requirements. The androgynous fastener provides a high-strength, reversible mechanical connection and may be used in high strength-to-weight ratio structural systems, such as lattice structure systems. The androgynous fastener resists tensile and shear forces upon loading of the lattice structure system thereby ensuring that the struts of the lattice structure system govern the mechanical behavior of the system. The androgynous fastener eliminates building-block orientation requirements and allows assembly in all orthogonal build directions. The androgynous fastener may be captive in building-block structural elements thereby minimizing the logistical complexity of transporting additional fasteners.