Patents by Inventor Christine Guo Lian

Christine Guo Lian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF CANCER
    Publication number: 20160271106
    Abstract: This disclosure provides agents, compositions and methods of treating cancer by inhibiting histone lysine specific demethylase 1 (LSD1) and/or and a histone lysine specific demethylase 2 (LSD2). Agents and compositions comprise statins and/or inhibitors of LSD1/2.
    Type: Application
    Filed: March 18, 2016
    Publication date: September 22, 2016
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Yujiang Geno Shi, Christine Guo Lian
  • Treatment of cancer
    Patent number: 9289415
    Abstract: This disclosure provides agents, compositions and methods of treating cancer by inhibiting histone lysine specific demethylase 1 (LSD1) and/or and a histone lysine specific demethylase 2 (LSD2). Agents and compositions comprise statins and/or inhibitors of LSD1/2.
    Type: Grant
    Filed: September 4, 2012
    Date of Patent: March 22, 2016
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Yujiang Geno Shi, Christine Guo Lian
  • SYSTEM AND METHOD FOR DETECTING CANCER
    Publication number: 20150285807
    Abstract: Disclosed herein are methods of detecting malignancy in a tumor of a subject comprising measuring the amount of 5-hmC in a tumor sample and comparing to a control to thereby detect a level of reduction of 5-hmC in the tumor, wherein the tumor is characterized as malignant if a threshold level of reduction is detected. The tumor may be a solid tumor such as a melanocytic lesion. Also disclosed are methods of determining the prognosis of a subject with a tumor by determination of the amount of 5-hmC in the tumor. Methods for treatment of a tumor with reduced 5-hmC are also disclosed.
    Type: Application
    Filed: June 11, 2013
    Publication date: October 8, 2015
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Yujiang Geno Shi, Christine Guo Lian
  • TREATMENT OF CANCER
    Publication number: 20140206757
    Abstract: This disclosure provides agents, compositions and methods of treating cancer by inhibiting histone lysine specific demethylase 1 (LSD1) and/or and a histone lysine specific demethylase 2 (LSD2). Agents and compositions comprise statins and/or inhibitors of LSD1/2.
    Type: Application
    Filed: September 4, 2012
    Publication date: July 24, 2014
    Applicant: THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Yujiang Geno Shi, Christine Guo Lian