Abstract: A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. The interface can be a rail including a neck portion connected to the body and a lip portion connected to the neck portion. The lip portion can be wider than the neck portion in a direction extending between the top and bottom surfaces of the implant. Methods of implanting the spacer and tools used during such procedure are also disclosed.

Abstract: A spinal fixation device that includes a first engagement member. The first engagement member includes a first body and at least one extension. The first body includes a first aperture for receipt of a fastener. The at least one extension extends outwardly from the first body. Also included in the device, a second engagement member including a second body and a threaded extension that extends from the second body. The second body includes a second aperture for receipt of a fastener. Further, an expansion ring including a first end and a second end is included. The first end includes a threaded surface in threaded communication with the threaded extension. The second end is in rotatable communication with the at least one extension of the first engagement member. Where a torque is applied to the expansion ring, the second engagement member moves with respect to the first engagement member.

Abstract: An expandable implant (210, 410) includes top and bottom plates (220, 250, 420, 450) having angled inner surfaces (222, 252, 422, 452) that interact with expansion members (300, 302, 500, 502). The expansion members (300, 302, 500, 502) may be situated on an actuator (280, 480), and may include at least one vertical projection (312, 314, 512, 514) for interacting with a recess (230, 430) in the plates (220, 250, 420, 450). In some instances, rotation of the actuator (280, 480) in opposing directions about a longitudinal axis may cause the expansion members (300, 302, 500, 502) to move toward or away from one another, thereby resulting in separation or collapse of the top and bottom plates (220, 250, 420, 450). Pins (316, 516) may also be associated with the expansion members (300, 302, 500, 502) and received in respective slots (318, 518) in the plates (220, 250, 420, 450).

Abstract: A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. Methods of implanting the spacer and tools used during such procedure are also disclosed.

Abstract: A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. Methods of implanting the spacer and tools used during such procedure are also disclosed.

Abstract: A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. Methods of implanting the spacer and tools used during such procedure are also disclosed.

Abstract: The present invention provides an advanced immunomagnetic method for the isolation of specific target cells from cell populations and suspensions of cell populations, espeacially tumor cells from peripheral blood bone, marrow aspirates, ascities and other body fluids. The invention also relates to a kit for performing the method for the isolation of specific target cells from body fluids.