Patents by Inventor Christine Jerome

Christine Jerome has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11541129
    Abstract: Disclosed herein are biomaterial implants, medical devices, or bioprostheses wherein a surface or part thereof is coated with a nanoreservoir comprising a hydrophilic polymer or copolymer backbone crosslinked to a second polymer comprising a hydrophilic backbone and one or more reactive moieties, wherein the nanoreservoir further comprises one or more bioactive molecules, therapeutic molecules, or drugs.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: January 3, 2023
    Assignee: UNIVERSITÉ DE LIÈGE
    Inventors: Cécile Oury, Christine Jérôme, Christophe Detrembleur, Patrizio Lancellotti
  • Publication number: 20220195117
    Abstract: The present invention relates to a curable isocyanate-free formulation for preparing a polyurethane self-blowing foam comprising at least one multifunctional cyclic carbonate having at least two cyclic carbonate groups at the end of the chain (compound A), at least one multifunctional amine (compound B), at least one multifunctional thiol (compound C) and at least one catalyst (compound D), to a process for preparing said foams, to the thus obtained foams and the recycling of said foams.
    Type: Application
    Filed: January 3, 2022
    Publication date: June 23, 2022
    Applicant: Universite de Liege
    Inventors: Christophe Detrembleur, Jean-Michel THOMASSIN, Bruno GRIGNARD, Florent MONIE, Christine JEROME
  • Patent number: 11261270
    Abstract: A polyvinyl alcohol has a number-average molecular weight (Mn) from 4,400 to 440,000, a molecular weight distribution (Mw/Mn) from 1.05 to 1.70, a degree of saponification from 80 to 99.99 mol %, wherein the polyvinyl alcohol contains an end group represented by a formula (I) below, and a molar ratio (X) of the end group based on total monomer units and the number-average molecular weight (Mn) satisfy a formula (1) below. Such a polyvinyl alcohol has a narrow molecular weight distribution and a high number-average molecular weight with hue good. (In the formula, R1 denotes an optionally substituted aromatic group having a carbon number from 6 to 20, and R2 denotes a hydrogen atom, an alkyl group having a carbon number from 1 to 20, or an optionally substituted aromatic group having a carbon number from 6 to 20.) X·Mn/44?0.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: March 1, 2022
    Assignees: KURARAY CO., LTD., UNIVERSITE DE LIEGE
    Inventors: Takumi Takayama, Kazuhiko Maekawa, Christophe Detrembleur, Antoine Debuigne, Christine Jerome
  • Patent number: 10766978
    Abstract: A polyvinyl alcohol is produced in a method comprising: a polymerization step comprising polymerizing vinyl ester monomers by controlled radical polymerization in the presence of a radical initiator and an organic cobalt complex to obtain a polymer solution containing a polyvinyl ester; an extraction step comprising extracting a cobalt complex from the polymer solution by contacting an aqueous solution containing a water-soluble ligand with the polymer solution; and a saponification step comprising saponifying the polyvinyl ester after the extraction step to obtain a polyvinyl alcohol. A method for producing a polyvinyl alcohol is thus provided that has a narrow molecular weight distribution and a high number-average molecular weight with good hue and further good solubility in water.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: September 8, 2020
    Assignees: KURARAY CO., LTD., UNIVERSITE DE LIEGE
    Inventors: Takumi Takayama, Yusuke Amano, Kazuhiko Maekawa, Christophe Detrembleur, Antoine Debuigne, Christine Jerome
  • Publication number: 20200216584
    Abstract: A polyvinyl alcohol has a number-average molecular weight (Mn) from 4,400 to 440,000, a molecular weight distribution (Mw/Mn) from 1.05 to 1.70, a degree of saponification from 80 to 99.99 mol %, wherein the polyvinyl alcohol contains an end group represented by a formula (I) below, and a molar ratio (X) of the end group based on total monomer units and the number-average molecular weight (Mn) satisfy a formula (1) below. Such a polyvinyl alcohol has a narrow molecular weight distribution and a high number-average molecular weight with hue good. (In the formula, R1 denotes an optionally substituted aromatic group having a carbon number from 6 to 20, and R2 denotes a hydrogen atom, an alkyl group having a carbon number from 1 to 20, or an optionally substituted aromatic group having a carbon number from 6 to 20.) X·Mn/44?0.
    Type: Application
    Filed: July 11, 2018
    Publication date: July 9, 2020
    Applicants: KURARAY CO., LTD., UNIVERSITE DE LIEGE
    Inventors: Takumi TAKAYAMA, Kazuhiko MAEKAWA, Christophe DETREMBLEUR, Antoine DEBUIGNE, Christine JEROME
  • Publication number: 20200085970
    Abstract: Nanoreservoirs and uses thereof, in particular the use of nanoreservoirs to coat a surface of a medical device, biomaterial or bioprosthetic.
    Type: Application
    Filed: December 28, 2017
    Publication date: March 19, 2020
    Applicant: Université de Liège
    Inventors: Cecile OURY, Christine JÈRÔME, Christophe DETREMBLEUR, Patrizio LANCELLOTTI
  • Publication number: 20190119414
    Abstract: A polyvinyl alcohol is produced in a method comprising: a polymerization step comprising polymerizing vinyl ester monomers by controlled radical polymerization in the presence of a radical initiator and an organic cobalt complex to obtain a polymer solution containing a polyvinyl ester; an extraction step comprising extracting a cobalt complex from the polymer solution by contacting an aqueous solution containing a water-soluble ligand with the polymer solution; and a saponification step comprising saponifying the polyvinyl ester after the extraction step to obtain a polyvinyl alcohol. A method for producing a polyvinyl alcohol is thus provided that has a narrow molecular weight distribution and a high number-average molecular weight with good hue and further good solubility in water.
    Type: Application
    Filed: March 30, 2017
    Publication date: April 25, 2019
    Applicants: KURARAY CO., LTD., UNIVERSITE DE LIEGE
    Inventors: Takumi TAKAYAMA, Yusuke AMANO, Kazuhiko MAEKAWA, Christophe DETREMBLEUR, Antoine DEBUIGNE, Christine JEROME
  • Publication number: 20140066537
    Abstract: The present invention relates an organic liquid composition comprising a mixture of a first polymer with a linear polymeric chain having two photoactive groups as endgroup; and a second polymer with a multifunctional polymeric chain having at least three photoactive groups, that can reversibly and repeatedly crosslink to form a solid polymer network wherein said liquid composition been crosslinked by irradiation with at least one wavelength L1 and been uncrosslinked at least locally by irradiating the network with at least one other wavelength L2 in order to repeatedly adjust shape and optical properties of said composition in its crosslinked state. The composition is applicable as a starting material for intraocular lenses and for other lenses and optical elements.
    Type: Application
    Filed: September 6, 2012
    Publication date: March 6, 2014
    Applicant: Universite De Liege
    Inventors: Christine Jerome, Rachid Jellali, Michaël Alexandre
  • Publication number: 20140046236
    Abstract: The present invention relates to a layered chitosan scaffold wherein said layered scaffold comprises at least two fused layers, wherein at least one of the fused layers comprises a chitosan nanofiber membrane and the other fused layer comprises a porous chitosan support layer. Moreover, the present invention provides a layered chitosan scaffold characterized by (i) a good adhesion between the porous and nanofiber layers, (ii) a tuneable porosity of the nanofiber layer by tuning the distance between the nanofibers, (iii) a stable nanofibers and porous morphology even when immersed in water or other solvents and a process for the preparation of such layered chitosan scaffold. The present invention also provides a process for the preparation of the layered chitosan scaffold.
    Type: Application
    Filed: May 24, 2011
    Publication date: February 13, 2014
    Applicant: UNIVERSITY OF LIEGE
    Inventors: Patrice Filée, Astrid Freichels, Christine Jéröme, Abdelhafid Aquil, Alain Colige, Victor Tchemtchoua Tateu
  • Publication number: 20130297040
    Abstract: The present invention relates to an implant comprising: —a core material comprising polydimethylsiloxane or at least one hydrogel polymer; —a tube encasing said core material comprising an ethylene vinyl acetate polymer or at least one hydrogel polymer; —a sealant for closure of the open ends of said tube comprising polydimethylsiloxane or a mono-, di-, or triacetoxy derivative thereof, or at least one hydrogel polymer; and —at least one active ingredient; wherein said at least one active ingredient is selected from the group comprising celecoxib, sulindac, tamoxifen, oestrogen, oestradiol, ethinyl oestradiol, mestranol, dienogest, norgestrel, levonorgestrel, desogestrel, norgestimate, ethynodiol diacetate, leuprorelin, buserelin, gonrelin, triptorelin, nafarelin, deslorelin, histrelin, and supprelin; and with the proviso that when the sealant is said at least one hydrogelpolymer, the core material comprises polydimethylsiloxane. Furthermore, the invention relates to an implant for use as a medicament.
    Type: Application
    Filed: January 16, 2012
    Publication date: November 7, 2013
    Applicants: UNIVERSITE DE LIEGE, UNIVERSITE CATHOLIQUE DE LOUVAIN
    Inventors: Jacques Donnez, Anne Van Langendonkt, Sylvie Defrère, Jean-Michel Foidart, Christine Jérome, Brigitte Evrard, Raphaël Riva, Fabrice Krier, Mélanie Mestdagt
  • Publication number: 20130261267
    Abstract: Process for the preparation of a halogenated polymer comprising a controlled radical polymerization step of at least one monomer containing at least one halogen-carbon bond, performed in the presence of an organo-cobalt complex, said polymerization step being further carried out in non-isotherm conditions.
    Type: Application
    Filed: December 6, 2011
    Publication date: October 3, 2013
    Applicant: Universite De Liege
    Inventors: Vincent Bodart, Yasmine Piette, Christophe Detrembleur, Antoine Debuigne, Christine Jerome
  • Publication number: 20110076658
    Abstract: A kit and method for promoting eye patch wear compliance for an afflicted child with a condition requiring wearing an eye patch are provided herein, including an eye patch kit for promoting patch wear compliance for an afflicted child with a condition requiring wearing an eye patch, comprising: a carrying case; at least one eye patch with a front surface and an adhesive back surface that is disposed to be worn over one eye, the eye patch comprising a stretchable and breathable material, and a black-out layer for total occlusion for shielding of light; a plurality of self adhesive stickers disposed to be attached to and decorate the eye patch on the front surface; and an instruction guide having explanation for decorating the eye patch.
    Type: Application
    Filed: September 30, 2009
    Publication date: March 31, 2011
    Applicant: SAVCO OPTICAL, INC.
    Inventors: Christine Jerome, Victor Jerome
  • Publication number: 20090020431
    Abstract: Electrografting method for forming and regulating a strongly adherent nanostructured polymer coating onto an electro-conductive surface profile characterized in that the surface profile is regulated by electrodeposition of nanometre- and/or micrometre-scale nuclei onto the surface profile prior to or simultaneously to the formation of the polymer coating.
    Type: Application
    Filed: January 31, 2007
    Publication date: January 22, 2009
    Inventors: Samuel Voccia, Harry Serwas, Christine Jerome, Robert Jerome
  • Publication number: 20040144655
    Abstract: Process for depositing by electrografting a strong adherent polymer coating onto an electrically conductive surface comprising the step of electrochemical grafting of an active monomer for forming a primer coating P onto the surface and having as general formula: X0 (meth)acrylate wherein X is either part of a preformed polymer or is an intermediate agent for polyaddition reaction or is an anchoring group for attachment of a molecule having at least one complementary reactive group. Such process allows formation of new primer by one-step electro-grafting of a macromonomer. Such process also allows further modification of an initial electrografted polymer to increase the coating thickness by the grafting-from technique. Such process also allows to graft onto the primer coating compounds like functional polymer, peptide, protein, oligonucleotide, dyes, drugs, anti-bacterian compounds.
    Type: Application
    Filed: December 4, 2003
    Publication date: July 29, 2004
    Inventors: Olivier Bertrand, Robert Jerome, Sandrine Gautier, Veronique Maquet, Christophe Detrembleur, Christine Jerome, Samuel Voccia, Michael Claes, Xudong Lou, David-Emmanuel Labaye