Abstract: A method within a computing execution environment for adding an aspect trigger for an aspect, an aspect being an application level abstraction relevant to a source or service, along with the execution environment, where the method includes defining service aspects; inserting or encapsulating the service aspects as named aspects into an abstraction layer in the computing execution environment; and associating the named aspects with the aspect trigger, wherein the abstraction layer is configured to associate aspect triggers for a plurality of client applications.

Abstract: A converged address book system having a converged address book (CAB) client for managing contact information, the CAB client including: an interface for interacting with a CAB server; and a synchronization interface for communicating with a synchronization module for interacting with a data synchronization enabler for synchronization between the CAB client and CAB server; the interface allowing the CAB client to manage contact information by making requests to and receiving responses from the CAB server. The CAB server including an interface for interacting with a CAB client; a data synchronization manager for synchronizing information between at least one CAB user device and the CAB server; a data synchronization interface for synchronizing data with the CAB client; a subscription manager for managing CAB subscription and authorization information; a document management interface for communicating with a CAB XMDS; and an XDMC for accessing and manipulate CAB data stored in the XDMS.

Abstract: The present invention relates to 15-desmethoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

Abstract: The present invention relates to 18,21-didesoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pre-treatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

Abstract: The present invention relates to 15-O-desmethylmacbecin analogues according to the formula (IA) or (IB) herein, or a pharmaceutically acceptable salt thereof: wherein: R1 and R2 either both represent H or together they represent a bond (i.e. C4 to C5 is a double bond); and R3 represents H or CONH2 that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

Abstract: A method and system for addressing a unique device from an address book, the method having the steps of: receiving a message having a root token and a secondary token; checking whether the root token exists within the address book, if no, creating a record in the address book with the root and secondary token; and if yes, checking whether the secondary token exists within the address book, if yes, providing a representation of the unique device; and if no, storing the secondary token against the root token in the address book.

Abstract: A context aware platform including a context aware server, the context aware server including: aspects, the aspects being application level abstractions related to a context; policies associated with a context at a point in an application lifecycle, the policies specifying behavior or treatment of aspects; and rules and triggers providing a sequence of steps or logic required to compute aspects; and at least one client, said client being in an execution environment and communicating with said context aware server, wherein the context aware platform replaces aspects, triggers, or both aspects and triggers in the at least one client.

Abstract: A method and system for the creation of aspects from a service or application, the method defining related service aspects; inserting or encapsulating service aspects as named aspects into an abstraction layer in an execution environment; and associating the named aspects with logic in the abstraction layer to support application or service function points.

Abstract: A method for execution in a computing execution environment for the creation of aspects from a service or application, an aspect being an application level abstraction relevant to a source or service, the method comprising: defining related service aspects; inserting or encapsulating service aspects as named aspects into a context aware layer in the execution environment, the context aware layer adapted to be called from a plurality of application types or services; and associating the named aspects with logic in the context aware layer to support application or service function points.

Abstract: The present invention relates to 11-O-desmethylmacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

Abstract: An interconnect for electrically connecting a first and second cell of a tubular fuel cell bundle having a body with an anode contact and a cathode contact extending therefrom. The anode contact is formed to follow a contour of an anode portion of the first cell. The cathode contact is formed to follow a contour of a cathode portion of the second cell. A contact aid may be applied to the anode contact and/or cathode contact for securing the contact to the respective portion of the fuel cell bundle. The interconnect preferably completes a series connection between the first and second cells.

Abstract: A method of making a food product includes—making a bread-type product by baking a dough, the composition of the dough being such that, after baking, the bread has a WA (water activity) that is higher than 0.90 and a water content comprised between 25 and 50%, making a garnish such as a cheese preparation, with a WA that is higher than 0.95 and a water content between 40 and 70% and associating the bread and the garnish in order to form the compound food product. When the food product is balanced, the bread and the garnish have a WA between 0.94 and 0.98 and a water content between 35 and 50%.

Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.

Abstract: The present invention provides a system, method and kit for teaching cooking, food and wine pairing, entertaining, travel, culture, and floral arranging to home chefs all contained within a single package. The package may contain any items necessary to teach the preparation and arranging of the dining experience. Further, the package can contain instructions and lists of perishable food items which may be needed for the dining experience.

Abstract: A CS31A protein capsule subunit having an aminoacid sequence modified by at least one heterologous peptide, the CS31A protein capsule comprising said subunit, and micro-organisms having the CS31A protein capsule with its subunit aminoacid sequence modified by at least one heterologous peptide, are disclosed. Methods for preparing said subunits, CS31A protein capsules comprising same, and micro-organisms having CS31A protein capsules, as well as the use thereof for preparing vaccines, producing peptides and preparing immunoassays, are also disclosed.