Patents by Inventor Christine Olson

Christine Olson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FGF ACTIVITY
    Publication number: 20240174631
    Abstract: The invention features compounds which modulate FGF activity, e.g., by enhancing the binding between FGF-2 and its receptors, e.g., FGF-R1. Also featured is a pharmaceutical composition containing one or more of the compounds, a method of treating an injury or a disease e.g., stroke, congenital hypogonadotropic hypogonadism, and viral infection, and a method of increasing spermatogenesis using the pharmaceutical composition.
    Type: Application
    Filed: February 11, 2022
    Publication date: May 30, 2024
    Inventors: Seth P. FINKLESTEIN, Gregory D. CUNY, Renato SKERLJ, Soumya RAY, Stephen Douglas BARRETT, Kirk Lang OLSON, Fred Lawrence CISKE, Paige Elizabeth HEIPLE, Melissa Christine HOLT, James Bernard KRAMER
  • Substituted bicyclic compounds useful as T cell activators
    Patent number: 11964973
    Abstract: Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR6 or N; Y is CR3 or N; R1, R2, R3, R4, R5, R6, R7, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK?) and diacylglycerol kinase zeta (DGK?), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: April 23, 2024
    Assignee: Bristol-Myers Squibb Company
    Inventors: Robert G. Gentles, Upender Velaparthi, Min Ding, Richard E. Olson, Scott W. Martin, Saumya Roy, Prasada Rao Jalagam, Jayakumar Sankara Warrier, Louis S. Chupak, Denise Christine Grunenfelder
  • Compositions and methods for inhibiting seizures
    Patent number: 11883441
    Abstract: Provided herein are methods and compositions related to treating or preventing seizures. In some aspects, provided herein are methods of treating or preventing seizures in a subject by administering to the subject a composition comprising Parabacteroides and Akkermansia bacteria.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: January 30, 2024
    Assignee: The Regents of the University of California
    Inventors: Elaine Y. Hsiao, Jessica Yano, Helen E. Vuong, Christine Olson
  • COMPOSITIONS AND METHODS FOR MODULATING COGNITIVE BEHAVIOR
    Publication number: 20220218762
    Abstract: The present disclosure provides methods of treating hypoxia-induced cognitive impairment. Also disclosed are microbiome modulators, such as ketogenic-diet-suppressed bacterial species or antibiotics effective against a ketogenic-diet-boosted bacterial species, for use in treatment of cognitive impairment. The disclosure also provides methods of selecting a subject having hypoxia-induced cognitive impairment and methods of obtaining a prognostic indicator of hypoxia-induced cognitive impairment in a subject who receives a dosage of a microbiome modulator.
    Type: Application
    Filed: June 1, 2020
    Publication date: July 14, 2022
    Inventors: Elaine Y. Hsiao, Christine Olson, Alonso Iniguez
  • COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES
    Publication number: 20220184144
    Abstract: Provided herein are methods and compositions related to treating or preventing seizures. In some aspects, provided herein are methods of treating or preventing seizures in a subject by administering to the subject a composition comprising Parabacteroides and Akkermansia bacteria.
    Type: Application
    Filed: September 27, 2021
    Publication date: June 16, 2022
    Inventors: Elaine Y. Hsiao, Jessica Yano, Helen E. Vuong, Christine Olson
  • METHODS OF SELECTING SUBJECTS FOR TREATMENT WITH METABOLOMIC MODULATORS
    Publication number: 20210364526
    Abstract: Provided herein are methods for selecting a subject with a disease or disorder for treatment, as well as methods of treating the subject, determining the efficacy of the treatment, and adjusting the treatment dosage and frequency.
    Type: Application
    Filed: May 22, 2019
    Publication date: November 25, 2021
    Inventors: Elaine Y Hsiao, Jessica Yano, Helen E. Vuong, Christine Olson
  • Compositions and methods for inhibiting seizures
    Patent number: 11129858
    Abstract: Provided herein are methods and compositions related to treating or preventing seizures. In some aspects, provided herein are methods of treating or preventing seizures in a subject by administering to the subject a composition comprising Parabacteroides and Akkermansia bacteria.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: September 28, 2021
    Assignee: The Regents of the University of California
    Inventors: Elaine Hsiao, Jessica Yano, Helen Vuong, Christine Olson
  • COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES
    Publication number: 20200384037
    Abstract: Provided herein are methods and compositions related to treating or preventing seizures. In some aspects, provided herein are methods of treating or preventing seizures in a subject by administering to the subject a composition comprising Parabacteroides and Akkermansia bacteria.
    Type: Application
    Filed: December 20, 2017
    Publication date: December 10, 2020
    Inventors: Elaine Hsiao, Jesscia Yano, Helen Vuong, Christine Olson