Patents by Inventor Christine Richardson

Christine Richardson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11008575
    Abstract: Disclosed herein are unique single stranded DNA oligonucleotide products identified as binding with high affinity and specificity to ovarian tumor cells that may be used in the delivery of therapy to and diagnosis of ovarian cancer.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: May 18, 2021
    Assignee: The University of North Carolina at Charlotte
    Inventors: Christine Richardson, Gregory Benedetto
  • Publication number: 20180258496
    Abstract: The present invention comprises novel methods, systems, devices, and kits to detect cancer in a patient using HOXC6. Methods and systems are presented herein to (1) determine differential gene expression in cancer tissue (e.g. human epithelial ovarian cancer) using Exon microarray analysis and confirm select gens using qPCR; (2) to correlate transcriptional expression from part 1 with potential protein using IHC; and (3) to confirm specific proteins in sera by ELISA process. In some embodiments, a ELISA kit is provided. More specifically, the inventors developed a cancer screen test based on significant changes in HOXC6 protein in blood serum of ovarian cancer human subjects. Industry available standard protocols and reagents for the detection of HOXC6 in patient blood serum provided highly variable results that would be unsatisfactory for clinical diagnostic testing and screening.
    Type: Application
    Filed: May 2, 2018
    Publication date: September 13, 2018
    Inventors: M. Taghi Mostafavi, Christine Richardson, Zahra Bahrani-Mostafavi, David L. Tait
  • Publication number: 20170233739
    Abstract: Disclosed herein are unique single stranded DNA oligonucleotide products identified as binding with high affinity and specificity to ovarian tumor cells that may be used in the delivery of therapy to and diagnosis of ovarian cancer.
    Type: Application
    Filed: February 20, 2017
    Publication date: August 17, 2017
    Inventors: Christine Richardson, Gregory Benedetto
  • Patent number: 9181865
    Abstract: An electrical generator has an internal combustion engine and an alternator mounted to the engine and operative to generate electrical power during running of the engine. The alternator and the engine are arranged vertically to reduce the footprint of the electrical generator. The components of the electrical generator are contained within an enclosure defined by a base panel, a set of upright side panels, and a roof panel. When the roof panel is removed, each of the side panels can be independently removed from engagement with the base panel, which allows for easier access to the components of the electrical generator, such as for maintenance, service, and repair. The components are arranged so that cooling and exhaust air flow paths are defined within the enclosure.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: November 10, 2015
    Assignee: Generae Power Systems, Inc.
    Inventors: Christine Richardson, Michael Bechtel, Joel Wray, Jonathan Gohde, Billy Brandenburg, Leonard Pilling
  • Publication number: 20150191798
    Abstract: The present invention comprises novel methods, systems, devices, and kits to detect cancer in a patient using HOXC6. Methods and systems are presented herein to (1) determine differential gene expression in cancer tissue (e.g. human epithelial ovarian cancer) using Exon microarray analysis and confirm select gens using qPCR; (2) to correlate transcriptional expression from part 1 with potential protein using IHC; and (3) to confirm specific proteins in sera by ELISA process. In some embodiments, a ELISA kit is provided. More specifically, the inventors developed a cancer screen test based on significant changes in HOXC6 protein in blood serum of ovarian cancer human subjects. Industry available standard protocols and reagents for the detection of HOXC6 in patient blood serum provided highly variable results that would be unsatisfactory for clinical diagnostic testing and screening.
    Type: Application
    Filed: March 19, 2015
    Publication date: July 9, 2015
    Inventors: M. Taghi Mostafavi, Christine Richardson, Zahra Bahrani-Mostafavi, David L. Tait
  • Publication number: 20140083349
    Abstract: A ribbon crystal pulling furnace has a base insulation and a liner insulation removably connected to the base insulation. At least a portion of the liner insulation forms an interior for containing a crucible.
    Type: Application
    Filed: September 21, 2012
    Publication date: March 27, 2014
    Applicant: MAX ERA, INC.
    Inventors: Richard L. WALLACE, David HARVEY, Weidong HUANG, Scott REITSMA, Christine RICHARDSON
  • Patent number: 8293007
    Abstract: A ribbon crystal pulling furnace has a base insulation and a liner insulation removably connected to the base insulation. At least a portion of the liner insulation forms an interior for containing a crucible.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: October 23, 2012
    Assignee: Max Era, Inc.
    Inventors: Richard Wallace, David Harvey, Weidong Huang, Scott Reitsma, Christine Richardson
  • Publication number: 20120125254
    Abstract: A method for reducing the range in resistivities of semiconductor crystalline sheets produced in a multi-lane growth furnace. A furnace for growing crystalline sheets is provided that includes a crucible with a material introduction region and a crystal growth region including a plurality of crystal sheet growth lanes. The crucible is configured to produce a generally one directional flow of material from the material introduction region toward the crystal sheet growth lane farthest from the material introduction region. Silicon doped with both a p-type dopant and an n-type dopant in greater than trace amounts is introduced into the material introduction region. The doped silicon forms a molten substance in the crucible called a melt. Crystalline sheets are formed from the melt at each growth lane in the crystal growth region. Co-doping the silicon feedstock can reduce the variation in resistivities among the crystalline sheets formed in each lane.
    Type: Application
    Filed: November 23, 2010
    Publication date: May 24, 2012
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Brian D. Kernan, Gary J. Tarnowski, Weidong Huang, Scott Reitsma, Christine Richardson
  • Publication number: 20110272952
    Abstract: An electrical generator has an internal combustion engine and an alternator mounted to the engine and operative to generate electrical power during running of the engine. The alternator and the engine are arranged vertically to reduce the footprint of the electrical generator. The components of the electrical generator are contained within an enclosure defined by a base panel, a set of upright side panels, and a roof panel. When the roof panel is removed, each of the side panels can be independently removed from engagement with the base panel, which allows for easier access to the components of the electrical generator, such as for maintenance, service, and repair. The components are arranged so that cooling and exhaust air flow paths are defined within the enclosure.
    Type: Application
    Filed: January 18, 2011
    Publication date: November 10, 2011
    Inventors: Christine Richardson, Michael Bechtel, Joel Wray, Jonathan Gohde, Billy Brandenburg, Leonard Pilling
  • Publication number: 20110247546
    Abstract: A ribbon crystal has a body with a width dimension, and string embedded within the body. The string has a generally elongated cross-sectional shape. This cross-section (of the string) has a generally longitudinal axis that diverges with the width dimension of the ribbon crystal body.
    Type: Application
    Filed: April 5, 2011
    Publication date: October 13, 2011
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Christine Richardson, Weidong Huang, Richard L. Wallace, Daniel Doble, Scott Reitsma
  • Publication number: 20110155045
    Abstract: A sheet wafer growth system includes a crucible for containing molten material and an afterheater positioned above the crucible. The afterheater has an inner surface disposed toward the crucible. The system further includes one or more shields adjacent to the inner surface of the afterheater. The afterheater and the shield(s) are configured to allow a sheet wafer to pass adjacent to the shield(s). Each shield has two or more substantially different thermally conductive regions such that the two or more regions are configured to control the temperature profile of the growing sheet wafer.
    Type: Application
    Filed: January 27, 2011
    Publication date: June 30, 2011
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Kaitlin Olsen, Weidong Huang, Christine Richardson
  • Patent number: 7842270
    Abstract: A string for use in a string ribbon crystal has a base portion with a refractory material, and an externally exposed layer radially outward of the refractory material. The base portion has a coefficient of thermal expansion that is generally matched with the coefficient of thermal expansion for silicon. The externally exposed layer has a contact angle with silicon of between about 15 and 120 degrees.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: November 30, 2010
    Assignee: Evergreen Solar, Inc.
    Inventors: Christine Richardson, Weidong Huang, Richard Wallace, Daniel Doble, Scott Reitsma
  • Patent number: 7727590
    Abstract: A hot wire chemical vapor deposition apparatus comprises a vacuum chamber, a substrate support member located in the vacuum chamber, a filament assembly support member located in the vacuum chamber, a precursor gas inlet located in the vacuum chamber and a device for providing a clean portion of at least one filament inside the vacuum chamber without breaking vacuum.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: June 1, 2010
    Assignee: California Institute of Technology
    Inventors: Christine Richardson, Harry A. Atwater
  • Publication number: 20100092776
    Abstract: A string for use in a string ribbon crystal has a base portion with a refractory material, and an externally exposed layer radially outward of the refractory material. The base portion has a coefficient of thermal expansion that is generally matched with the coefficient of thermal expansion for silicon. The externally exposed layer has a contact angle with silicon of between about 15 and 120 degrees.
    Type: Application
    Filed: December 9, 2009
    Publication date: April 15, 2010
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Christine Richardson, Weidong Huang, Richard Wallace, Daniel Doble, Scott Reitsma
  • Publication number: 20100055412
    Abstract: A method of forming a string for use in a string ribbon crystal provides a refractory metal as a core for the string and forms a first layer of material on the core. A method of growing a ribbon crystal provides a pair of strings. Each string has a refractory metal core. The method further passes the strings through a molten material to grow the ribbon crystal between the pair of strings. A ribbon crystal wafer includes a ribbon crystal material and a pair of strings in the ribbon crystal material. Each string defines an outer edge of the wafer, and each string includes a refractory metal core.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 4, 2010
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Christine Richardson, Lawrence Felton
  • Patent number: 7651768
    Abstract: A string for use in a string ribbon crystal has a base portion with a refractory material, and an externally exposed layer radially outward of the refractory material. The base portion has a coefficient of thermal expansion that is generally matched with the coefficient of thermal expansion for silicon. The externally exposed layer has a contact angle with silicon of between about 15 and 120 degrees.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: January 26, 2010
    Assignee: Evergreen Solar, Inc.
    Inventors: Christine Richardson, Weidong Huang, Richard Wallace, Daniel Doble, Scott Reitsma
  • Publication number: 20090318714
    Abstract: The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula VI, or a salt thereof, wherein R1, R2, R3 and R? are as defined in the specification, and processes of manufacturing this compound including intermediates.
    Type: Application
    Filed: November 6, 2006
    Publication date: December 24, 2009
    Inventors: John Mykytiuk, Ludovic Bonnet, Stephen Gorsuch, Osamu Ichihara, Richard Mears, Christine Richardson
  • Patent number: 7591257
    Abstract: A fuel selection device is provided for allowing a user to connect the cylinders of an internal combustion engine to a user-selected fuel source. The fuel selection device includes a housing that defines a cavity for receiving a moveable selector therein. The selector defining first, second, third and fourth flow paths. The first and second flow paths are used for flowing a first type (e.g., natural gas) of fuel from a fuel source to the cylinders of the engine. The second and fourth flow paths are used for flowing a second type of fuel (e.g., liquid propane vapor) from a fuel source to the cylinder. The selector is movable between a first position wherein first and second cylinders communicate with the first and second flow paths, respectively, and a second position wherein the first and second cylinders communicate with the second flow path and fourth flow paths, respectively.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: September 22, 2009
    Assignee: Generac Power Systems, Inc.
    Inventors: Don R. Bayer, Chris Turner, Christine A. Richardson, Robert D. Kern
  • Publication number: 20090061224
    Abstract: A method of making string for string ribbon crystal provides a substrate having an outer surface, and extrudes refractory material over the substrate. The refractory material substantially covers the outer surface of the substrate. The method then cures the refractory material.
    Type: Application
    Filed: August 29, 2008
    Publication date: March 5, 2009
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Christine Richardson, Lawrence Felton
  • Publication number: 20090060823
    Abstract: A string for use in a string ribbon crystal has a base portion with a refractory material, and an externally exposed layer radially outward of the refractory material. The base portion has a coefficient of thermal expansion that is generally matched with the coefficient of thermal expansion for silicon. The externally exposed layer has a contact angle with silicon of between about 15 and 120 degrees.
    Type: Application
    Filed: August 29, 2008
    Publication date: March 5, 2009
    Applicant: EVERGREEN SOLAR, INC.
    Inventors: Christine Richardson, Weidong Huang, Richard Wallace, Daniel Doble, Scott Reitsma