Patents by Inventor Christine Schieber
Christine Schieber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11712301Abstract: A method of generating a 4D model includes capturing imagery of a catheter and a vessel as the catheter is directed through the vessel to a location of interest, wherein the catheter is disposed on a guidewire, constructing a 3D time varying reference curve describing a trajectory of the guidewire, and constructing a time varying 3D model of the artery using the reference curve.Type: GrantFiled: April 8, 2019Date of Patent: August 1, 2023Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry Halupka, Stephen M. Moore, Christine Schieber
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Patent number: 11660141Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.Type: GrantFiled: January 20, 2020Date of Patent: May 30, 2023Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
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Patent number: 11621087Abstract: Method and apparatus for predicting amyloid beta (A?) and phosphorylated tau (p-tau) biomarker levels in the cerebrospinal fluid (CSF) of patients. Embodiments include determining current values for a plurality of easily-measurable attributes of a first patient. Embodiments include analyzing data associated with a cohort of patients having known measurements of A? and p-tau biomarker levels, including determined values for the plurality of easily-measureable attributes. Embodiments include generating a predicted value for A? and/or p-tau biomarker levels for the first patient. Embodiments include generating a risk of the first patient developing AD at a future time, generating a probability of a patient's predicted rate of decline, and/or generating a probability of a patient's age at the onset of dementia, based on the predicted values for A? and/or p-tau biomarker levels.Type: GrantFiled: September 24, 2019Date of Patent: April 4, 2023Assignee: International Business Machines CorporationInventors: Benjamin Goudey, Annalisa Jean Swan, Noel Garry Faux, Roslyn Hickson, Christine Schieber, Bowen Fung
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Patent number: 11413629Abstract: In one example, a method includes providing a pulp composed of a combination of particulate materials including particles of a target material. The pulp is mixed with a collector composed of anisotropic particles having at least two separate spatial domains that have different physiochemical properties, and the mixture of pulp and collector is fed into an aqueous solution containing air bubbles.Type: GrantFiled: September 23, 2019Date of Patent: August 16, 2022Assignee: International Business Machines CorporationInventors: Julia Baldauf, Alexe Bojovschi, Benjamin S. Mashford, Christine Schieber, George Yiapanis
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Patent number: 11170031Abstract: A method, computer system, and a computer program product for automatically extracting and normalizing at least one mutant gene entity from at least one set of unstructured text is provided. The present invention may include extracting the unstructured text describing first and second entities. The present invention may then include identifying a specific first entity and a specific second entity. The present invention may also include associating the specific first and the specific second entities. The present invention may further include creating the mutant gene entity. The present invention may then include identifying at least one semantic relationship between the created mutant gene entity and one or more third entities. The present invention may further include storing the at least one set of data associated with the specific first and specific second entity, the semantic relationship, and the created mutant gene entity in a database.Type: GrantFiled: August 31, 2018Date of Patent: November 9, 2021Assignee: International Business Machines CorporationInventors: Richard L. Martin, Antonio Jose Jimeno Yepes, David Martinez Iraola, Alix Lacoste, Christine Schieber
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Patent number: 11026583Abstract: A catheter including a monitoring body and a pair of markers disposed on the monitoring body, each marker of the pair of markers encircling the monitoring body, wherein the pair of markers are configured to indicate, through their appearance from a given point of view, an orientation of the monitoring body.Type: GrantFiled: April 26, 2017Date of Patent: June 8, 2021Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry Halupka, Stephen M. Moore, Christine Schieber
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Publication number: 20210090746Abstract: Method and apparatus for predicting amyloid beta (A?) and phosphorylated tau (p-tau) biomarker levels in the cerebrospinal fluid (CSF) of patients. Embodiments include determining current values for a plurality of easily-measurable attributes of a first patient. Embodiments include analyzing data associated with a cohort of patients having known measurements of A? and p-tau biomarker levels, including determined values for the plurality of easily-measureable attributes. Embodiments include generating a predicted value for A? and/or p-tau biomarker levels for the first patient. Embodiments include generating a risk of the first patient developing AD at a future time, generating a probability of a patient's predicted rate of decline, and/or generating a probability of a patient's age at the onset of dementia, based on the predicted values for A? and/or p-tau biomarker levels.Type: ApplicationFiled: September 24, 2019Publication date: March 25, 2021Inventors: Benjamin Goudey, Annalisa Jean Swan, Noel Faux, Roslyn Hickson, Christine Schieber, Bowen Fung
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Publication number: 20200163720Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.Type: ApplicationFiled: January 20, 2020Publication date: May 28, 2020Inventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
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Publication number: 20200073995Abstract: A method, computer system, and a computer program product for automatically extracting and normalizing at least one mutant gene entity from at least one set of unstructured text is provided. The present invention may include extracting the unstructured text describing first and second entities. The present invention may then include identifying a specific first entity and a specific second entity. The present invention may also include associating the specific first and the specific second entities. The present invention may further include creating the mutant gene entity. The present invention may then include identifying at least one semantic relationship between the created mutant gene entity and one or more third entities. The present invention may further include storing the at least one set of data associated with the specific first and specific second entity, the semantic relationship, and the created mutant gene entity in a database.Type: ApplicationFiled: August 31, 2018Publication date: March 5, 2020Inventors: Richard L. Martin, Antonio Jose Jimeno Yepes, David Martinez Iraola, Alix Lacoste, Christine Schieber
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Patent number: 10568697Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.Type: GrantFiled: December 31, 2017Date of Patent: February 25, 2020Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
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Patent number: 10568696Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.Type: GrantFiled: July 17, 2017Date of Patent: February 25, 2020Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
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Publication number: 20200037978Abstract: A system for estimating fractional flow reserve (FFR) includes a front end application to receive image frames from an imaging system to develop a model of a vasculature system based on an observed concentration time profile at locations within the model using contrast dye in the vasculature system and movement of the vasculature system. A graphics processing unit is configured to represent a computed concentration time profile in the vasculature system using a Lattice-Boltzmann Method (LBM) to generate a representation of the vasculature system. A dynamic controller tunes a velocity field based on a mismatch between the observed concentration time profile and the computed concentration time profile at the locations within the model to obtain a best estimate of the velocity field to perform a FFR measurement.Type: ApplicationFiled: October 10, 2019Publication date: February 6, 2020Inventors: Darcy Beurle, Colin Compas, Stephen Moore, Christine Schieber, Sergiy Zhuk
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Publication number: 20200016609Abstract: In one example, a method includes providing a pulp composed of a combination of particulate materials including particles of a target material. The pulp is mixed with a collector composed of anisotropic particles having at least two separate spatial domains that have different physiochemical properties, and the mixture of pulp and collector is fed into an aqueous solution containing air bubbles.Type: ApplicationFiled: September 23, 2019Publication date: January 16, 2020Inventors: Julia Baldauf, Alexe Bojovschi, Benjamin S. Mashford, Christine Schieber, George Yiapanis
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Patent number: 10492754Abstract: A system for estimating fractional flow reserve (FFR) includes a front end application to receive image frames from an imaging system to develop a model of a vasculature system based on an observed concentration time profile at locations within the model using contrast dye in the vasculature system and movement of the vasculature system. A graphics processing unit is configured to represent a computed concentration time profile in the vasculature system using a Lattice-Boltzmann Method (LBM) to generate a representation of the vasculature system. A dynamic controller tunes a velocity field based on a mismatch between the observed concentration time profile and the computed concentration time profile at the locations within the model to obtain a best estimate of the velocity field to perform a FFR measurement.Type: GrantFiled: November 20, 2015Date of Patent: December 3, 2019Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Darcy Beurle, Colin Compas, Stephen Moore, Christine Schieber, Sergiy Zhuk
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Patent number: 10464075Abstract: In one example, a method includes providing a pulp composed of a combination of particulate materials including particles of a target material. The pulp is mixed with a collector composed of anisotropic particles having at least two separate spatial domains that have different physiochemical properties, and the mixture of pulp and collector is fed into an aqueous solution containing air bubbles.Type: GrantFiled: December 22, 2015Date of Patent: November 5, 2019Assignee: International Business Machines CorporationInventors: Julia Baldauf, Alexe Bojovschi, Benjamin S. Mashford, Christine Schieber, George Yiapanis
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Patent number: 10390888Abstract: A method of generating a 4D model includes capturing imagery of a catheter and a vessel as the catheter is directed through the vessel to a location of interest, wherein the catheter is disposed on a guidewire, constructing a 3D time varying reference curve describing a trajectory of the guidewire, and constructing a time varying 3D model of the artery using the reference curve.Type: GrantFiled: December 29, 2017Date of Patent: August 27, 2019Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry Halupka, Stephen M. Moore, Christine Schieber
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Publication number: 20190231438Abstract: A method of generating a 4D model includes capturing imagery of a catheter and a vessel as the catheter is directed through the vessel to a location of interest, wherein the catheter is disposed on a guidewire, constructing a 3D time varying reference curve describing a trajectory of the guidewire, and constructing a time varying 3D model of the artery using the reference curve.Type: ApplicationFiled: April 8, 2019Publication date: August 1, 2019Inventors: JULIA S. BALDAUF, DARCY J. BEURLE, MATTHEW DOWNTON, KERRY HALUPKA, STEPHEN M. MOORE, CHRISTINE SCHIEBER
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Patent number: 10252920Abstract: Data relating to fluid dynamics is obtained using a flow field sensor that measures acceleration and angular velocity of the sensor on three axes. Ballast control allows the sensor to obtain neutral buoyancy within the fluid. The sensor is effective in opaque fluids and closed containers as data is stored in a removable memory. Froth flotation systems are among the applications for the sensor. The small size, the geometry, and the center of mass of the sensor allow it to follow the flow field in a vessel without material disruption of the flow field or weight-induced angular displacement.Type: GrantFiled: September 7, 2015Date of Patent: April 9, 2019Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy James Beurle, Matthew Downton, Stephen M. Moore, Christine Schieber, George Yiapanis
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Patent number: 10251708Abstract: A method of generating a 4D model includes capturing imagery of a catheter and a vessel as the catheter is directed through the vessel to a location of interest, wherein the catheter is disposed on a guidewire, constructing a 3D time varying reference curve describing a trajectory of the guidewire, and constructing a time varying 3D model of the artery using the reference curve.Type: GrantFiled: April 26, 2017Date of Patent: April 9, 2019Assignee: International Business Machines CorporationInventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry Halupka, Stephen M. Moore, Christine Schieber
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Publication number: 20190015158Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.Type: ApplicationFiled: July 17, 2017Publication date: January 17, 2019Inventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber