Patents by Inventor Christine SEGUIN

Christine SEGUIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040110814
    Abstract: The purpose of the invention concerns a family of pseudodipeptides which are coupling products between tryptamine, an indole-primary amine, and a selection of alpha-amino acids, the said pseudodipeptides having the following general formula (I) 1
    Type: Application
    Filed: October 2, 2003
    Publication date: June 10, 2004
    Applicant: EXSYLMOL S.A.M.
    Inventor: Marie-Christine Seguin
  • Patent number: 6716436
    Abstract: A cosmetic composition for slimming which includes, in combination with a cosmetically acceptable excipient, at least one compound having the formula (I) where R1 is a group bound by a peptidic bond and selected from the group consisting of a hydrogen atom, a hydroxyl group, an acyl group, acyloxy group and a substituted or unsubstituted aminoacid; R2 is a group bond by a peptidic bond and selected from the group consisting of a hydroxyl group, an amine group, an alkoxy group, an alkylamine group, a silyloxy group or a substituted or unsubstituted aminoacid; and n is 3 or 4.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: April 6, 2004
    Assignee: Exsymol S.A.M.
    Inventor: Marie-Christine Seguin
  • Publication number: 20030190327
    Abstract: The present invention relates to an algal adduct of the citrullinylarginine natural dipeptide as well as to its dermatological use and the use of chemical analogs issued from the same dipeptide displaying no toxic potential, as skin and phanera care and treatment agents, the said analogs having the following general formula (I) 1
    Type: Application
    Filed: April 2, 2003
    Publication date: October 9, 2003
    Inventor: Marie-Christine Seguin
  • Patent number: 6335457
    Abstract: The invention concerns a complex containing biologically assimilable orthosilicic acid and a process of preparation of said complex. In this complex, orthosilicic acid is complexed with a polypeptide and the complex is under solid, stable and concentrated form. The present invention also concerns cosmetic or therapeutic compositions, and a nutritional supplement containing said complex.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: January 1, 2002
    Assignee: Exsymol S.A.M.
    Inventors: Marie-Christine Seguin, Jean Gueyne
  • Patent number: 6280715
    Abstract: Cosmetic composition useful notably in the whitening of skin which it includes, in association with any suitable excipient, at least one compound of the following general formula (I): wherein: R1 represents a hydrogen atom, a linear or branched alkyl group or a thiazoline group, R2 represents a hydrogen atom, a linear or branched alkyl group or a linear or branched alkyl group substituted by a carboxyl, a hydroxyl, an amine or a thiol group, R3 represents a hydrogen atom, a linear or branched alkyl group, an arylalkyl group, an acyl group or an acyloxy group, R4 represents a hydrogen atom or a linear or branched alkyl group, R5 represents a hydrogen atom, a hydroxyl group or a linear or branched alkyl group.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: August 28, 2001
    Assignees: Exsymol S.A.M.
    Inventors: Marie-Christine Seguin, Mark A. Babizhayev
  • Patent number: 6211393
    Abstract: Silicon compound of general formula a), in which A, B, C, D are radicals which are different from OH and are covalently bonded to Si; two or three of these bond that are linked to Si are Si—O—C, Si—S—C or Si—N—C type bonds and are hydrolyzable in vivo, forming Si—OH bonds that are biologically active especially when in contact with living tissue, the A and D bonds of formula b) being invariably hydrolyzable; at least one of the hydrolyzable bonds corresponds to an acyloxy, aryloxy or vinyloxy radical; at least one of the compounds obtained after hydrolysis of the hydrolyzable bonds is a stabilizer, and the non-hydrolyzable bonds, which are of the Si—C type, correspond to hydrocarbon or fluorocarbon radicals for which Si is not directly linked to the phenyl ring.
    Type: Grant
    Filed: July 22, 1996
    Date of Patent: April 3, 2001
    Assignee: Exsymol S.A.M.
    Inventors: Marie Christine Seguin, Jean Gueyne, Jean-Francois Nicolay, Andre Franco
  • Patent number: 6197986
    Abstract: Organo silicon compound having the following general formula (I): R4—Si (OR1) (OR2) (R3)  (I) where R1 and R2 each one independently represent an atom of hydrogen or an alkyl group, R3 represents an hydrogen atom, an hydroxyl group, an amine group, an alkyl group, an alkoxy or a carboxylate group, and at least one of the OR1, OR2 or R3 groups represents an hydroxyl group, R4 represents an alkyl group substituted or not by a functional group such as, notably, an alkyl phosphate group or an alkyl phosphonate group, or any other group for which the R4—Si bond is not hydrolyzable, and the compound: is in solid form, and/or is possibly associated with at least one stabilizer, and/or is possibly associated with at least one dispersant.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: March 6, 2001
    Assignee: Exsymol S.A.M.
    Inventors: Marie-Christine Seguin, Jean Gueyne
  • Patent number: 6172250
    Abstract: A process for the preparation of biologically active silicon compounds by hydrolysis of a precursor which produces a compound which prevents the formation of polymers from the silicon hydrolyzed bonds.
    Type: Grant
    Filed: July 16, 1996
    Date of Patent: January 9, 2001
    Assignee: Exsymol S.A.M.
    Inventors: Marie-Christine Seguin, Jean Gueyne, Jean-Francois Nicolay, Andre Franco
  • Patent number: 6046340
    Abstract: Product pseudodipeptide of general formula: ##STR1## in which A is: a) under the form: ##STR2## B represent an amine which nitrogen atom which is directly linked to the atom of carbon and chosen among the amines, the imines, the ammoniums,R is an atom of fluorine, a fluoro-alkyl radical, a functional group, an acyl radical, a linear alkyl chain, or an alkenyle or aryl radical,R' is an hydrogen atom, a fluorine atom, an alkyl radical, or fluoro-alkyl radical, andIm is an imidazole or an N-substituted imidazole ring;b) or the form of ##STR3## where R is an atom of hydrogen or a fluoro-alkyl or an acyl radical, or an hydrocarbon radical which can be substituted by one or several functional groups, and R" is a hydrocarbon radical or an acyle radical.
    Type: Grant
    Filed: July 18, 1996
    Date of Patent: April 4, 2000
    Assignee: Exsymol Societe Anonyme Monegasque
    Inventors: Marie-Christine Seguin, Marc Babizhayev
  • Patent number: 6007203
    Abstract: Process of assessment of ocular dysfunctions, characterized in that the patient's eye (1) is placed to a previously defined distance from a lightening glare source (3), so that he can visualize a target (4) placed next to the lightening glare source (3), then the target (4) is approached from the source (3) so that the patient becomes unable to distinguish the target (4) from the source (3) and then, the target (4) is slowly taken away from the source (3), up to the exact moment when the patient distinguishes again the target (4), and at this time, the incident light angle o between the source (3) and the target (4) is measured.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: December 28, 1999
    Assignees: Exsymol S.A.M., Mark A. Babizhayev
    Inventors: Marie-Christine Seguin, Mark A. Babizhayev
  • Patent number: 6001389
    Abstract: A method of treatment of osteo-articular disease which includes administering an effective amount of a pharmaceutical composition containing a compound of specified formula and an excipient to a patient in need of such treatment. The compounds of specified formula have a phosphonate group on one end and a silanol or silanol precursor on the opposite end, and can inhibit serine proteases.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: December 14, 1999
    Inventors: Marie-Christine Seguin, Jean Gueyne
  • Patent number: 5792784
    Abstract: The invention relates to a pseudo-dipeptide product obtained by coupling between histamine or methyl-substituted histamine and an amino-acid having formula ##STR1## wherein A is a radical selected in the group comprising amine radicals, amides, lactames, urethans; R.sub.1, R'.sub.1, R.sub.2, R'.sub.2. . . R.sub.n, R'.sub.n represent each a hydrogen atom, a hydrocarbon radical or a functional group; Y and Z represent each a hydrogen or a fluorine atom, or a hydrocarbon radical which may be substituted by one or a plurality of functional groups; and n is an integer higher than or equal to 1; the covalent bond with the histamine or the methyl-substituted histamine being a peptide bond between the carboxylic radical of the amino acid and the amine radical of the histamine. The pseudo-dipeptide products of the invention may be used in therapeutical, cosmetological and agro-alimentary applications and particularly for the treatment of cataracts.
    Type: Grant
    Filed: August 21, 1995
    Date of Patent: August 11, 1998
    Assignees: Marc Babizhayev, Exsymol Societe Anonyme Monegasque
    Inventors: Marie-Christine Seguin, Marc Babizhayev
  • Patent number: 5609878
    Abstract: Insecticide composition, especially a pediculicide, comprising as active agent, rotenone or reduced rotenone. The composition is characterized in that said agent is bound to small polymer spherules. The retonone and/or reduced is preferably at least 90% pure. The composition may be in the form of a suspension, an emulsion, a powder, a paste, a cream or a foam and the like. The novel composition is useful in the treatment of parasites in both humans and animals.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: March 11, 1997
    Inventors: Jean Gueyne, Marie-Christine Seguin
  • Patent number: 5264207
    Abstract: Products for cutaneous application with cosmetic and/or therapeutic effects, containing one or more active substances. This or these substances are carried by the microspheres of a polymer, dispersed in a liquid in which this polymer is not soluble.
    Type: Grant
    Filed: July 17, 1990
    Date of Patent: November 23, 1993
    Assignee: EXSYMOL S.A.M.
    Inventors: Jean Bommelaer, Andre Franco, Jean Gueyne, Marie-Christine Seguin
  • Patent number: 5087452
    Abstract: Therapeutic product based on an organic derivative of silicon, particularly useful in the treatment of vascular diseases. The organic silicon compound is associated with a polyamine carrying hydrocarbon chains including carboxyl groups.
    Type: Grant
    Filed: April 4, 1990
    Date of Patent: February 11, 1992
    Inventors: Jean Gueyne, Marie-Christine Seguin, Gilbert H. Crussol
  • Patent number: 5085870
    Abstract: Aqueous composition for care of the superficial lymphatic vessels, containing one or more silanols or silanol derivatives in conjunction with concholytic acid.
    Type: Grant
    Filed: September 5, 1990
    Date of Patent: February 4, 1992
    Inventors: Marie-Christine Seguin, Jean Gueyne
  • Patent number: 5037803
    Abstract: Process of preparation of an organo-silicon cosmetic compound having cosmetic and cutaneous resorption activity, derived from the addition or combination or complexing of a silanol with a substance which determines its cosmetic activity and an intracutaneous fixation substance.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: August 6, 1991
    Inventors: Jean Gueyne, Marie-Christine Seguin, Jacques Bondon
  • Patent number: 4985405
    Abstract: Therapeutic produced based on an organic derivative of silicon, notably of silanol complexed with an amino acid, with a pharmaceutically acceptable salt of such an acid, or with a protide. The produce is suitable for the preparation of medicaments for activation and regulation of metabolism and of growth and of multiplication of cells, in particular those which are involved in the immuno-processes or in the formation of conjunctive and bone tissue.
    Type: Grant
    Filed: February 3, 1988
    Date of Patent: January 15, 1991
    Inventors: Jean Gueyne, Marie-Christine Seguin, Jean-Georges Henrotte
  • Patent number: 4927952
    Abstract: Product of condensation of a silanol or a silanol derivative, which comprises an Si atom carrying two organic radicals and two oxygen atoms connected to organic groups other than the radicals; at least one of these organic groups carries at least one NH and a NH.sub.2.
    Type: Grant
    Filed: May 24, 1988
    Date of Patent: May 22, 1990
    Assignee: Exsymol S.A.M.
    Inventors: Jean Gueyne, Marie-Christine Seguin
  • Patent number: 4784854
    Abstract: Cosmetic composition for treatment of the skin, comprising conjuctive tissue cells, particularly fibroblasts, in a nutrient medium, in which growth of the cells can occur. Flat support having an adhesive coated periphery, carrying or containing this composition, covered with a film insoluble in water. Preparation of the composition by the culture of fibroblasts in a modified Eagle medium.
    Type: Grant
    Filed: July 29, 1986
    Date of Patent: November 15, 1988
    Inventors: Marie-Christine Seguin, Jean Gueyne