Patents by Inventor Christine Trinkle

Christine Trinkle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell culture device and methods of use thereof
    Patent number: 11326138
    Abstract: Provided herein is a tissue culture device and a method of forming a tissue culture device. The tissue culture device includes a microfluidic layer including at least one hydrophobic microchannel and a reservoir portion over the at least one hydrophobic microchannel, the reservoir portion including an opening aligned with the at least one hydrophobic microchannel. The method of forming a tissue culture device includes providing a microfluidic layer mold, a reservoir layer mold, and a removable lid mold, filling each of the molds with a device material, curing the device material within the molds, removing the cured device material from the molds to provide a microfluidic layer, a reservoir layer, and a removable lid, and bonding the microfluidic layer to the reservoir layer. A method of culturing tissue with the tissue culture device is also provided herein.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: May 10, 2022
    Assignee: University of Kentucky Research Foundation
    Inventors: Christine Trinkle, Ren Xu, Soroosh Torabi
  • CELL CULTURE DEVICE AND METHODS OF USE THEREOF
    Publication number: 20180312792
    Abstract: Provided herein is a tissue culture device and a method of forming a tissue culture device. The tissue culture device includes a microfluidic layer including at least one hydrophobic microchannel and a reservoir portion over the at least one hydrophobic microchannel, the reservoir portion including an opening aligned with the at least one hydrophobic microchannel. The method of forming a tissue culture device includes providing a microfluidic layer mold, a reservoir layer mold, and a removable lid mold, filling each of the molds with a device material, curing the device material within the molds, removing the cured device material from the molds to provide a microfluidic layer, a reservoir layer, and a removable lid, and bonding the microfluidic layer to the reservoir layer. A method of culturing tissue with the tissue culture device is also provided herein.
    Type: Application
    Filed: May 1, 2018
    Publication date: November 1, 2018
    Inventors: Christine Trinkle, Ren Xu, Soroosh Torabi