Patents by Inventor CHRISTINE V. HAWKINS

CHRISTINE V. HAWKINS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR IDENTIFYING PROTEASES, PROTEASE TARGET SITES AND REGULATORS OF PROTEASE ACTIVITY IN CELLS
    Publication number: 20020132327
    Abstract: The invention provides a fusion protein including a reporter polypeptide linked to a linker polypeptide comprising a protease cleavage site, and a repressor polypeptide that represses the activity of the reporter polypeptide. The repressor polypeptide is operatively linked to the linker polypeptide. Cleavage of the linker polypeptide at the protease cleavage site increases the activity of said reporter. A method is also provided for identifying a protease that recognizes a specific protease cleavage site. The invention further provides a method of identifying a compound that activities a protease.
    Type: Application
    Filed: March 17, 1999
    Publication date: September 19, 2002
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: BRUCE A. HAY, CHRISTINE V. HAWKINS